We report the presence of peculiar nonbanded calcification of the cornea in three patients with acquired immunodeficiency syndrome, discovered on postmortem histological examination of the globes. In one patient, multiple calcium salt precipitates also affected other ocular and orbital structures. Calcium deposits were present in the corneal stroma but spared Bowman's layer, as is usually seen in primary and secondary corneal calcification. The calcified areas were positive to von Kossa, alizarin red, alcian blue, and colloidal iron stains. Electron probe analysis of the three cases showed the presence of calcium and phosphorus in a ratio characteristic for hydroxyapatite. No predisposing factors could be found. The possible role of associated alterations in the mucopolysaccharide content or composition in the calcified areas is unclear.

Acquired immunodeficiency syndrome and ocular calcification / Pecorella, Irene; M. C., Cartney Ace; S., Lucas; R., Miller; K., Brady; Ciardi, Antonio; U., Di Tondo; A., Garner. - In: CORNEA. - ISSN 0277-3740. - STAMPA. - 15:3(1996), pp. 305-311. [10.1097/00003226-199605000-00013]

Acquired immunodeficiency syndrome and ocular calcification

PECORELLA, Irene;CIARDI, Antonio;
1996

Abstract

We report the presence of peculiar nonbanded calcification of the cornea in three patients with acquired immunodeficiency syndrome, discovered on postmortem histological examination of the globes. In one patient, multiple calcium salt precipitates also affected other ocular and orbital structures. Calcium deposits were present in the corneal stroma but spared Bowman's layer, as is usually seen in primary and secondary corneal calcification. The calcified areas were positive to von Kossa, alizarin red, alcian blue, and colloidal iron stains. Electron probe analysis of the three cases showed the presence of calcium and phosphorus in a ratio characteristic for hydroxyapatite. No predisposing factors could be found. The possible role of associated alterations in the mucopolysaccharide content or composition in the calcified areas is unclear.
acquired immunodeficiency syndrome; calcification; glycosaminoglycans
01 Pubblicazione su rivista::01a Articolo in rivista
Acquired immunodeficiency syndrome and ocular calcification / Pecorella, Irene; M. C., Cartney Ace; S., Lucas; R., Miller; K., Brady; Ciardi, Antonio; U., Di Tondo; A., Garner. - In: CORNEA. - ISSN 0277-3740. - STAMPA. - 15:3(1996), pp. 305-311. [10.1097/00003226-199605000-00013]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/109446
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