Objective. Jaccoud’s arthropathy (JA) is a deforming, non-erosive arthri- tis, occurring in 2–35% of systemic lupus erythematosus (SLE) patients. We aimed to evaluate JA patients in a wide monocentric SLE cohort in terms of clinical, serological and ultrasono- graphic features. Methods. Consecutive SLE patients (ACR criteria 1997) were evaluated. The JA index was applied for patients with reducible deformities. Patients with a JA index ≥5 underwent physi - cal examination, blood testing and ul- trasound (US) assessment. Detection of anti-citrullinated protein antibodies (ACPA) and rheumatoid factor (RF) was performed. A single rheumatologist performed the US assessment of bilat - eral wrist and hands . Results. Four hundred and eighty SLE patients were evaluated: 17 (3.5%) showed a JA index ≥5 (M:F 1:16; mean age±SD 50.7±11.1 years; mean disease duration±SD 247.8±116.2 months). Four patients (23.5%) showed ACPA positivity. Fifteen patients (88.2%) showed at least one US abnormality. Bone erosions were found in 10 patients (58.8%). ACPA+ve patients showed erosive damage more frequently in at least one joint compared with ACPA-ve

Jaccoud's arthropathy in systemic lupus erythematosus: clinical, laboratory and ultrasonographic features / Ceccarelli, F; Massaro, L; Perricone, C; Pendolino, M; Cipriano, E; Truglia, S; Miranda, F; Spinelli, Fr; Alessandri, C; Valesini, G; Conti, F. - In: CLINICAL AND EXPERIMENTAL RHEUMATOLOGY. - ISSN 0392-856X. - STAMPA. - 35:4(2017), pp. 674-677.

Jaccoud's arthropathy in systemic lupus erythematosus: clinical, laboratory and ultrasonographic features

Ceccarelli, F;Massaro, L;Perricone, C;Pendolino, M;Cipriano, E;Truglia, S;Miranda, F;Spinelli, FR;Alessandri, C;Valesini, G;Conti, F
2017

Abstract

Objective. Jaccoud’s arthropathy (JA) is a deforming, non-erosive arthri- tis, occurring in 2–35% of systemic lupus erythematosus (SLE) patients. We aimed to evaluate JA patients in a wide monocentric SLE cohort in terms of clinical, serological and ultrasono- graphic features. Methods. Consecutive SLE patients (ACR criteria 1997) were evaluated. The JA index was applied for patients with reducible deformities. Patients with a JA index ≥5 underwent physi - cal examination, blood testing and ul- trasound (US) assessment. Detection of anti-citrullinated protein antibodies (ACPA) and rheumatoid factor (RF) was performed. A single rheumatologist performed the US assessment of bilat - eral wrist and hands . Results. Four hundred and eighty SLE patients were evaluated: 17 (3.5%) showed a JA index ≥5 (M:F 1:16; mean age±SD 50.7±11.1 years; mean disease duration±SD 247.8±116.2 months). Four patients (23.5%) showed ACPA positivity. Fifteen patients (88.2%) showed at least one US abnormality. Bone erosions were found in 10 patients (58.8%). ACPA+ve patients showed erosive damage more frequently in at least one joint compared with ACPA-ve
File allegati a questo prodotto
File Dimensione Formato  
Ceccarelli_Jaccoud’s arthropathy_2017.pdf

solo gestori archivio

Tipologia: Altro materiale allegato
Licenza: Tutti i diritti riservati (All rights reserved)
Dimensione 254.32 kB
Formato Adobe PDF
254.32 kB Adobe PDF   Visualizza/Apri   Richiedi una copia

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/11573/1093940
Citazioni
  • ???jsp.display-item.citation.pmc??? ND
  • Scopus 14
  • ???jsp.display-item.citation.isi??? 13
social impact