It is well known that cytomegalovirus (CMV) coinfection affects a large proportion of people with HIV, with a significant impact on disease progression and survival [1]. In HIV-CMV coinfected pregnant women, however, few studies have been conducted: maternal immunosuppression has been linked to a higher risk of CMV infant infection, and CMV DNAaemia to higher maternal and infant mortality [2,3]. Overall, little is known about pregnancy outcomes and CMV viraemia in CMV-coinfected pregnant women with HIV. To further explore this issue, the impact of CMV coinfection was evaluated on pregnancy outcomes in a national cohort of pregnant women with HIV, assessing in a study subsample the prevalence and correlates of CMV DNAaemia in HIV-CMV coinfected pregnant women.

Pregnancy outcomes and cytomegalovirus DNAaemia in HIV-infected pregnant women with CMV / Ravizza, M.; Tamburrini, E.; Mori, F.; Ortolani, P.; dalle Nogare, E. R.; Di Lorenzo, F.; Sterrantino, G.; Meli, M.; Polemi, S.; Nocentini, J.; Baldini, M.; Montorzi, G.; Mazzetti, M.; Rogasi, P.; Borchi, B.; Vichi, F.; Del Pin, B.; Pinter, E.; Anzalone, E.; Marocco, R.; Mastroianni, C.; Mercurio, V. S.; Carocci, A.; Grilli, E.; Maccabruni, A.; Zaramella, M.; Mariani, B.; Natalini Raponi, G.; Guaraldi, G.; Nardini, G.; Stentarelli, C.; Beghetto, B.; Degli Antoni, A. M.; Molinari, A.; Crisalli, M. P.; Donisi, A.; Piepoli, M.; Cerri, V.; Zuccotti, G.; Giacomet, V.; Coletto, S.; Di Nello, F.; Madia, C.; Placido, G.; Vivarelli, A.; Castelli, P.; Savalli, F.; Portelli, V.; Sabbatini, F.; Francisci, D.; Bernini, L.; Grossi, P.; Rizzi, L.; Alberico, S.; Maso, G.; Airoud, M.; Soppelsa, G.; Meloni, A.; Dedoni, M.; Cuboni, C.; Ortu, F.; Piano, P.; Citernesi, A.; Bordoni Vicini, I.; Luzi, K.; Spinillo, A.; Roccio, M.; Vimercati, A.; Miccolis, A.; De Gennaro, A.; Guerra, B.; Cervi, F.; Simonazzi, G.; Margarito, E.; Capretti, M. G.; Marsico, C.; Faldella, G.; Sansone, M.; Martinelli, P.; Agangi, A.; Capone, A.; Maruotti, G. M.; Tibaldi, C.; Trentini, L.; Todros, T.; Masuelli, G.; Frisina, V.; Cetin, I.; Brambilla, T.; Savasi, V.; Personeni, C.; Giaquinto, C.; Fiscon, M.; Rubino, E.; Bucceri, A.; Matrone, R.; Scaravelli, G.; Genovese, O.; Cafforio, C.; Pinnetti, C.; Liuzzi, G.; Tozzi, V.; Massetti, P.; Casadei, A. M.; Cavaliere, A. F.; Cellini, M.; Castelli Gattinara, G.; Marconi, A. M.; Dalzero, S.; Sacchi, V.; Ierardi, M.; Polizzi, C.; Mattei, A.; Pirillo, M. F.; Amici, R.; Galluzzo, C. M.; Donnini, S.; Baroncelli, S.; Floridia, M.; Villani, P.; Cusato, M.; Cerioli, A.; De Martino, M.; Mastroiacovo, P.; Parazzini, F.; Vella, S.. - In: CLINICAL MICROBIOLOGY AND INFECTION. - ISSN 1198-743X. - 22:9(2016), pp. 818-820. [10.1016/j.cmi.2016.06.017]

Pregnancy outcomes and cytomegalovirus DNAaemia in HIV-infected pregnant women with CMV

Pinter, E.;Mastroianni, C.;DAL MASO, GIANNI;Massetti, P.;
2016

Abstract

It is well known that cytomegalovirus (CMV) coinfection affects a large proportion of people with HIV, with a significant impact on disease progression and survival [1]. In HIV-CMV coinfected pregnant women, however, few studies have been conducted: maternal immunosuppression has been linked to a higher risk of CMV infant infection, and CMV DNAaemia to higher maternal and infant mortality [2,3]. Overall, little is known about pregnancy outcomes and CMV viraemia in CMV-coinfected pregnant women with HIV. To further explore this issue, the impact of CMV coinfection was evaluated on pregnancy outcomes in a national cohort of pregnant women with HIV, assessing in a study subsample the prevalence and correlates of CMV DNAaemia in HIV-CMV coinfected pregnant women.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/1092155
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