Bone formation is impaired in both type 1 and type 2 diabetes (T2D) while sclerostin, an antagonist of bone formation, is increased in T2D only. No data are available on latent autoimmune diabetes in adults (LADA), an autoimmune type of diabetes that may clinically resemble T2D at diagnosis. We evaluated serum sclerostin and bone turnover markers in LADA compared with T2D, and whether sclerostin is affected by metabolic syndrome (MetS) in T2D or LADA.

Serum sclerostin and bone turnover in latent autoimmune diabetes in adults / Napoli, Nicola; Strollo, Rocky; Defeudis, Giuseppe; Leto, Gaetano; Moretti, Chiara; Zampetti, Simona; D'Onofrio, Luca; Campagna, Giuseppe; Palermo, Andrea; Greto, Valentina; Manfrini, Silvia; Hawa, Mohammed I; Leslie, R David; Pozzilli, Paolo; Buzzetti, Raffaella. - In: THE JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM. - ISSN 0021-972X. - (2018), pp. 1921-1928. [10.1210/jc.2017-02274]

Serum sclerostin and bone turnover in latent autoimmune diabetes in adults

Defeudis, Giuseppe;Leto, Gaetano;Moretti, Chiara;Zampetti, Simona;D'Onofrio, Luca;Campagna, Giuseppe;Palermo, Andrea;Pozzilli, Paolo;Buzzetti, Raffaella
2018

Abstract

Bone formation is impaired in both type 1 and type 2 diabetes (T2D) while sclerostin, an antagonist of bone formation, is increased in T2D only. No data are available on latent autoimmune diabetes in adults (LADA), an autoimmune type of diabetes that may clinically resemble T2D at diagnosis. We evaluated serum sclerostin and bone turnover markers in LADA compared with T2D, and whether sclerostin is affected by metabolic syndrome (MetS) in T2D or LADA.
.
01 Pubblicazione su rivista::01a Articolo in rivista
Serum sclerostin and bone turnover in latent autoimmune diabetes in adults / Napoli, Nicola; Strollo, Rocky; Defeudis, Giuseppe; Leto, Gaetano; Moretti, Chiara; Zampetti, Simona; D'Onofrio, Luca; Campagna, Giuseppe; Palermo, Andrea; Greto, Valentina; Manfrini, Silvia; Hawa, Mohammed I; Leslie, R David; Pozzilli, Paolo; Buzzetti, Raffaella. - In: THE JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM. - ISSN 0021-972X. - (2018), pp. 1921-1928. [10.1210/jc.2017-02274]
File allegati a questo prodotto
File Dimensione Formato  
Napoli_Serum-sclerotin_2018.pdf

solo gestori archivio

Tipologia: Versione editoriale (versione pubblicata con il layout dell'editore)
Licenza: Tutti i diritti riservati (All rights reserved)
Dimensione 285.55 kB
Formato Adobe PDF
285.55 kB Adobe PDF   Visualizza/Apri   Richiedi una copia

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/1086113
Citazioni
  • ???jsp.display-item.citation.pmc??? 14
  • Scopus 26
  • ???jsp.display-item.citation.isi??? 24
social impact