Fourty-eight cluster headache patients have been studied. Twenty-nine of them were affected also by rhythm cardiac abnormalities, and the other 19 by associated conjunctival hyperaemia. The presence of organ-specific autoantibodies was investigated by immunofluorescence. High titers of antibodies against cardiac antigenic determinants was found. The study of leukocyte subpopulations revealed a parallel increase in blood and in conjunctival mucosa of Leu7+ and LeuM3+ cells. These outcomes confirm the immunopathological theory of cluster headache.
[Aspects of organ-specific autoimmunity in cluster headache] / Giacovazzo, Mario; DI SABATO, Francesco; M. L., Ruggirei; Martelletti, Paolo. - In: RIVISTA EUROPEA PER LE SCIENZE MEDICHE E FARMACOLOGICHE. - ISSN 0392-291X. - 11:4(1989), pp. 301-305.
[Aspects of organ-specific autoimmunity in cluster headache].
GIACOVAZZO, Mario;DI SABATO, Francesco;MARTELLETTI, Paolo
1989
Abstract
Fourty-eight cluster headache patients have been studied. Twenty-nine of them were affected also by rhythm cardiac abnormalities, and the other 19 by associated conjunctival hyperaemia. The presence of organ-specific autoantibodies was investigated by immunofluorescence. High titers of antibodies against cardiac antigenic determinants was found. The study of leukocyte subpopulations revealed a parallel increase in blood and in conjunctival mucosa of Leu7+ and LeuM3+ cells. These outcomes confirm the immunopathological theory of cluster headache.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
