Several techniques and protocols of non-invasive transcranial brain stimulation (NIBS), including transcranial magnetic and electrical stimuli, have been developed in the past decades. Non-invasive transcranial brain stimulation may modulate cortical excitability outlasting the period of non-invasive transcranial brain stimulation itself from several minutes to more than one hour. Quite a few lines of evidence, including pharmacological, physiological and behavioral studies in humans and animals, suggest that the effects of non-invasive transcranial brain stimulation are produced through effects on synaptic plasticity. However, there is still a need for more direct and conclusive evidence. The fragility and variability of the effects are the major challenges that non-invasive transcranial brain stimulation currently faces. A variety of factors, including biological variation, measurement reproducibility and the neuronal state of the stimulated area, which can be affected by factors such as past and present physical activity, may influence the response to non-invasive transcranial brain stimulation. Work is ongoing to test whether the reliability and consistency of non-invasive transcranial brain stimulation can be improved by controlling or monitoring neuronal state and by optimizing the protocol and timing of stimulation.

Plasticity induced by non-invasive transcranial brain stimulation: a position paper / Huang, Ying-Zu; Lu, Ming-Kue; Antal, Andrea; Classen, Joseph; Nitsche, Michael; Ziemann, Ulf; Ridding, Michael; Hamada, Masashi; Ugawa, Yoshikazu; Jaberzadeh, Shapour; Suppa, Antonio; Paulus, Walter; Rothwell, John. - In: CLINICAL NEUROPHYSIOLOGY. - ISSN 1872-8952. - 128:11(2017), pp. 2318-2329. [10.1016/j.clinph.2017.09.007]

Plasticity induced by non-invasive transcranial brain stimulation: a position paper

Suppa, Antonio;
2017

Abstract

Several techniques and protocols of non-invasive transcranial brain stimulation (NIBS), including transcranial magnetic and electrical stimuli, have been developed in the past decades. Non-invasive transcranial brain stimulation may modulate cortical excitability outlasting the period of non-invasive transcranial brain stimulation itself from several minutes to more than one hour. Quite a few lines of evidence, including pharmacological, physiological and behavioral studies in humans and animals, suggest that the effects of non-invasive transcranial brain stimulation are produced through effects on synaptic plasticity. However, there is still a need for more direct and conclusive evidence. The fragility and variability of the effects are the major challenges that non-invasive transcranial brain stimulation currently faces. A variety of factors, including biological variation, measurement reproducibility and the neuronal state of the stimulated area, which can be affected by factors such as past and present physical activity, may influence the response to non-invasive transcranial brain stimulation. Work is ongoing to test whether the reliability and consistency of non-invasive transcranial brain stimulation can be improved by controlling or monitoring neuronal state and by optimizing the protocol and timing of stimulation.
2017
NIBS; Plasticity, repetitive transcranial magnetic stimulation (rTMS); Transcranial direct current stimulation (tDCS); Transcranial electrical stimulation (TED); Variability; Brain; Humans; Neuronal Plasticity; Transcranial Direct Current Stimulation; Transcranial Magnetic Stimulation; Sensory Systems; Neurology; Neurology (clinical); Physiology (medical)
01 Pubblicazione su rivista::01g Articolo di rassegna (Review)
Plasticity induced by non-invasive transcranial brain stimulation: a position paper / Huang, Ying-Zu; Lu, Ming-Kue; Antal, Andrea; Classen, Joseph; Nitsche, Michael; Ziemann, Ulf; Ridding, Michael; Hamada, Masashi; Ugawa, Yoshikazu; Jaberzadeh, Shapour; Suppa, Antonio; Paulus, Walter; Rothwell, John. - In: CLINICAL NEUROPHYSIOLOGY. - ISSN 1872-8952. - 128:11(2017), pp. 2318-2329. [10.1016/j.clinph.2017.09.007]
File allegati a questo prodotto
File Dimensione Formato  
Huang_plasticity-induced_2017.pdf

accesso aperto

Tipologia: Versione editoriale (versione pubblicata con il layout dell'editore)
Licenza: Creative commons
Dimensione 548.22 kB
Formato Adobe PDF
548.22 kB Adobe PDF

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/1081025
Citazioni
  • ???jsp.display-item.citation.pmc??? 76
  • Scopus 271
  • ???jsp.display-item.citation.isi??? 244
social impact