Paediatric low-grade gliomas (pLGGs) are a heterogeneous group of brain tumours associated with a high overall survival: however, they are prone to recur and supratentorial lesions are difficult to resect, being associated with high percentage of disease recurrence. Our aim was to shed light on the biology of pLGGs.

The miR-139-5p regulates proliferation of supratentorial paediatric low-grade gliomas by targeting the PI3K/AKT/mTORC1 signalling / Catanzaro, Giuseppina; Besharat, Zein Mersini; Miele, Evelina; Chiacchiarini, Martina; Po, Agnese; Carai, Andrea; Marras, Carlo Efisio; Antonelli, Manila; Badiali, Manuela; Raso, Alessandro; Mascelli, Samantha; Schrimpf, Daniel; Stichel, Damian; Tartaglia, Marco; Capper, David; von Deimling, Andreas; Giangaspero, Felice; Mastronuzzi, Angela; Locatelli, Franco; Ferretti, Elisabetta. - In: NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY. - ISSN 0305-1846. - ELETTRONICO. - 44:7(2018), pp. 687-706. [10.1111/nan.12479]

The miR-139-5p regulates proliferation of supratentorial paediatric low-grade gliomas by targeting the PI3K/AKT/mTORC1 signalling

Catanzaro, Giuseppina
Primo
;
Besharat, Zein Mersini
Secondo
;
Miele, Evelina;CHIACCHIARINI, MARTINA;Po, Agnese;Antonelli, Manila
Methodology
;
Badiali, Manuela;Giangaspero, Felice
;
Mastronuzzi, Angela;Locatelli, Franco
Penultimo
;
Ferretti, Elisabetta
Ultimo
2018

Abstract

Paediatric low-grade gliomas (pLGGs) are a heterogeneous group of brain tumours associated with a high overall survival: however, they are prone to recur and supratentorial lesions are difficult to resect, being associated with high percentage of disease recurrence. Our aim was to shed light on the biology of pLGGs.
2018
PI3K/AKT/mTORC1; paediatric low-grade gliomas; miR-139-5p; microRNAs; patients’ derived primary cells; supratentorial
01 Pubblicazione su rivista::01a Articolo in rivista
The miR-139-5p regulates proliferation of supratentorial paediatric low-grade gliomas by targeting the PI3K/AKT/mTORC1 signalling / Catanzaro, Giuseppina; Besharat, Zein Mersini; Miele, Evelina; Chiacchiarini, Martina; Po, Agnese; Carai, Andrea; Marras, Carlo Efisio; Antonelli, Manila; Badiali, Manuela; Raso, Alessandro; Mascelli, Samantha; Schrimpf, Daniel; Stichel, Damian; Tartaglia, Marco; Capper, David; von Deimling, Andreas; Giangaspero, Felice; Mastronuzzi, Angela; Locatelli, Franco; Ferretti, Elisabetta. - In: NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY. - ISSN 0305-1846. - ELETTRONICO. - 44:7(2018), pp. 687-706. [10.1111/nan.12479]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/1079614
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