Phosphodiesterase 2A, a cAMP-hydrolysing enzyme, is essential for mouse development, however the cause of Pde2A knockout embryonic lethality is unknown. To understand if Pde2A plays a role in cardiac development, hearts of Pde2A deficient embryos were analysed at different stage of development.
Critical role of phosphodiesterase 2A in mouse congenital heart defects / Assenza, Maria Rita; Barbagallo, Federica; Barrios, Florencia; Cornacchione, Marisa; Campolo, Federica; Vivarelli, Elisabetta; Gianfrilli, Daniele; Auletta, Luigi; Soricelli, Andrea; Isidori, Andrea; Lenzi, Andrea; Pellegrini, Manuela; Naro, Fabio.. - In: CARDIOVASCULAR RESEARCH. - ISSN 1755-3245. - ELETTRONICO. - 114:6(2018), pp. 830-845. [10.1093/cvr/cvy030]
Critical role of phosphodiesterase 2A in mouse congenital heart defects
Assenza Maria Rita;Barbagallo Federica;Barrios Florencia;Cornacchione Marisa;Campolo Federica;Vivarelli Elisabetta;Gianfrilli Daniele;Isidori Andrea M;Lenzi Andrea;Naro Fabio.
2018
Abstract
Phosphodiesterase 2A, a cAMP-hydrolysing enzyme, is essential for mouse development, however the cause of Pde2A knockout embryonic lethality is unknown. To understand if Pde2A plays a role in cardiac development, hearts of Pde2A deficient embryos were analysed at different stage of development.| File | Dimensione | Formato | |
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