We report a case of positive Philadelphia chromosome adult acute lymphoblastic leukaemia with a novel unbalanced translocation t(17;19), leading to trisomy of 17q21-qter. The patient did not obtain complete haematological response and died a few months after diagnosis. The significance of the 17q21-qter trisomy, resulting from this novel translocation, and its possible role in the progression of the leukaemia is discussed

Molecular cytogenetics characterization of a novel translocation involving chromosome 17 and 19 in a Ph+ adult lymphoblastic leukemia / Specchia, G; Albano, F; Anelli, L; Storlazzi, Ct; Cimino, Giuseppe; Liso, A; Zagaria, A; Liso, V; Rocchi, M.. - In: BRITISH JOURNAL OF HAEMATOLOGY. - ISSN 0007-1048. - 119:(2002), pp. 488-491.

Molecular cytogenetics characterization of a novel translocation involving chromosome 17 and 19 in a Ph+ adult lymphoblastic leukemia

CIMINO, Giuseppe;
2002

Abstract

We report a case of positive Philadelphia chromosome adult acute lymphoblastic leukaemia with a novel unbalanced translocation t(17;19), leading to trisomy of 17q21-qter. The patient did not obtain complete haematological response and died a few months after diagnosis. The significance of the 17q21-qter trisomy, resulting from this novel translocation, and its possible role in the progression of the leukaemia is discussed
2002
01 Pubblicazione su rivista::01a Articolo in rivista
Molecular cytogenetics characterization of a novel translocation involving chromosome 17 and 19 in a Ph+ adult lymphoblastic leukemia / Specchia, G; Albano, F; Anelli, L; Storlazzi, Ct; Cimino, Giuseppe; Liso, A; Zagaria, A; Liso, V; Rocchi, M.. - In: BRITISH JOURNAL OF HAEMATOLOGY. - ISSN 0007-1048. - 119:(2002), pp. 488-491.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/105461
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