Enkephalin Interaction with reactive oxygen species has been investigated. All the peptides tested exhibited hydroxyl radical and superoxide anion scavenging ability. Enkephalins undergo an oxidative modification by Fenton systems. The tyrosine amino-terminal residue is attacked by hydroxyl radical, being converted to dopa. The overall transformation produced opiomelanin pigments. This oxidative process provides evidence of a possible route for opiomelanin synthesis.
Interaction of enkephalins with oxyradicals / Fontana, Mario; Mosca, Luciana; Rosei, Maria Anna. - In: CELLULAR AND MOLECULAR BIOLOGY. - ISSN 0145-5680. - STAMPA. - 46:(2000), pp. 57-57. (Intervento presentato al convegno 3rd World Congress on Cellular and Molecular Biology tenutosi a Jena nel 8-13 ottobre 2001).
Interaction of enkephalins with oxyradicals.
FONTANA, Mario;MOSCA, Luciana;ROSEI, Maria Anna
2000
Abstract
Enkephalin Interaction with reactive oxygen species has been investigated. All the peptides tested exhibited hydroxyl radical and superoxide anion scavenging ability. Enkephalins undergo an oxidative modification by Fenton systems. The tyrosine amino-terminal residue is attacked by hydroxyl radical, being converted to dopa. The overall transformation produced opiomelanin pigments. This oxidative process provides evidence of a possible route for opiomelanin synthesis.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
