Catalogo dei prodotti della ricerca

HepatitisCvirus(HCV)infectionremainsoneofthemaincausesofchronicliverdiseaseworldwide.Theadventofdirect-actingantivirals(DAAs)hassignificantlyimprovedthecourseofpatientswithchronicHCVinfection(CHC),duetotheabilityofthesedrugstoachievehighratesofsustainedvirologicalresponse(SVR).TheseexceedinglyhighratesofSVRandtheexcellentsafetydatahavebeenconfirmedinreallifepractice.Evolvingguidelineshavebeenissuedbynationalandinternationalscientificsoci-etiesinaccordancewiththeprogressionofclinicalknowledgeandtheavailabilityofnewDAAs.Theserecommendations,however,maynotbeapplieduniversallybecauseofdelaysindrugsreimbursabilityindifferentcountriesandbecausesomeNationalHealthSystemsidentifyonlypatientswithadvanceddiseaseasatreatmentpriority.ItalyinthisregardisaprototypeaboutDAAstreatmentofCHCpatients.WiththeaimtoassesstheItaliantreatmentexperiencewithDAAsandtorespondtounmetneedsintreatmentoptimizationofantiviraltherapyinspecificsettingsofCHCpatients,agroupofItalianexpertsmetinStresainFebruary2017.Thesummaryoftheconsiderationsarisingfromthistwo-daymeetingandsomestatementsregardingafewopenissuesarereportedinthispositionpaper.©2017EditriceGastroenterologicaItalianaS.r.l.PublishedbyElsevierLtd.Allrightsreserved.

Treatment of Hepatitis C virus infection in Italy: A consensus report from an expert panel / Viganã², Mauro; Perno, Carlo Federico; Craxã¬, Antonio; Aghemo, Alessio; Alberti, Alfredo; Andreone, Pietro; Andreoni, Massimo; Bonora, Stefano; Brunetto, Maurizia Rossana; Bruno, Raffaele; Bruno, Savino; Calvaruso, Vincenza; Caporaso, Nicola; Ceccherini-Silberstein, Francesca; Cento, Valeria; Ciancio, Alessia; Colombatto, Piero; Degasperi, Elisabetta; Di Marco, Vito; Di Perri, Giovanni; D'Offizi, Gianpiero; Fagiuoli, Stefano; Ferrari, Carlo; Gaeta, Giovanni Battista; Pellicelli, Adriano; Petta, Salvatore; Piovesan, Sara; Puoti, Massimo; Raimondo, Giovanni; Russo, Francesco Paolo; Taliani, Gloria; Trama, Ugo; Villa, Erica; Zignego, Anna Linda. - In: DIGESTIVE AND LIVER DISEASE. - ISSN 1590-8658. - 49:7(2017), pp. 731-741. [10.1016/j.dld.2017.03.027]

Treatment of Hepatitis C virus infection in Italy: A consensus report from an expert panel

Caporaso, Nicola;Taliani, Gloria;
2017

Abstract

HepatitisCvirus(HCV)infectionremainsoneofthemaincausesofchronicliverdiseaseworldwide.Theadventofdirect-actingantivirals(DAAs)hassignificantlyimprovedthecourseofpatientswithchronicHCVinfection(CHC),duetotheabilityofthesedrugstoachievehighratesofsustainedvirologicalresponse(SVR).TheseexceedinglyhighratesofSVRandtheexcellentsafetydatahavebeenconfirmedinreallifepractice.Evolvingguidelineshavebeenissuedbynationalandinternationalscientificsoci-etiesinaccordancewiththeprogressionofclinicalknowledgeandtheavailabilityofnewDAAs.Theserecommendations,however,maynotbeapplieduniversallybecauseofdelaysindrugsreimbursabilityindifferentcountriesandbecausesomeNationalHealthSystemsidentifyonlypatientswithadvanceddiseaseasatreatmentpriority.ItalyinthisregardisaprototypeaboutDAAstreatmentofCHCpatients.WiththeaimtoassesstheItaliantreatmentexperiencewithDAAsandtorespondtounmetneedsintreatmentoptimizationofantiviraltherapyinspecificsettingsofCHCpatients,agroupofItalianexpertsmetinStresainFebruary2017.Thesummaryoftheconsiderationsarisingfromthistwo-daymeetingandsomestatementsregardingafewopenissuesarereportedinthispositionpaper.©2017EditriceGastroenterologicaItalianaS.r.l.PublishedbyElsevierLtd.Allrightsreserved.
2017
Antiviral treatment; Cirrhosis; Direct-acting antiviral agents; Hepatitis C; RAV; Treatment failure; Hepatology; Gastroenterology
01 Pubblicazione su rivista::01a Articolo in rivista
Treatment of Hepatitis C virus infection in Italy: A consensus report from an expert panel / Viganã², Mauro; Perno, Carlo Federico; Craxã¬, Antonio; Aghemo, Alessio; Alberti, Alfredo; Andreone, Pietro; Andreoni, Massimo; Bonora, Stefano; Brunetto, Maurizia Rossana; Bruno, Raffaele; Bruno, Savino; Calvaruso, Vincenza; Caporaso, Nicola; Ceccherini-Silberstein, Francesca; Cento, Valeria; Ciancio, Alessia; Colombatto, Piero; Degasperi, Elisabetta; Di Marco, Vito; Di Perri, Giovanni; D'Offizi, Gianpiero; Fagiuoli, Stefano; Ferrari, Carlo; Gaeta, Giovanni Battista; Pellicelli, Adriano; Petta, Salvatore; Piovesan, Sara; Puoti, Massimo; Raimondo, Giovanni; Russo, Francesco Paolo; Taliani, Gloria; Trama, Ugo; Villa, Erica; Zignego, Anna Linda. - In: DIGESTIVE AND LIVER DISEASE. - ISSN 1590-8658. - 49:7(2017), pp. 731-741. [10.1016/j.dld.2017.03.027]
01a Articolo in rivista
File allegati a questo prodotto
File Dimensione Formato  
Viganò_treatment-hepatitis_2017.pdf

accesso aperto

Tipologia: Documento in Post-print (versione successiva alla peer review e accettata per la pubblicazione)
Licenza: Tutti i diritti riservati (All rights reserved)
Dimensione 813.58 kB
Formato Adobe PDF
813.58 kB Adobe PDF

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/1040428
Citazioni
  • ???jsp.display-item.citation.pmc??? 3
  • Scopus 16
  • ???jsp.display-item.citation.isi??? 15
social impact