There is a worldwide-accepted evidence of a population shift toward older ages. This shift favors an increased risk of developing lung cancer that is primarily a disease of older populations. Decision making is extremely difficult in elderly patients, since this group is under-represented in clinical trials with only 25% of them historically opening to patients older than 65 years. For all these reasons, a "customized" preoperative assessment to identify physiological or pathological frailty should be encouraged since standard tools may be less reliable. The work already done to improve patient selection for lung surgery in the elderly population clearly shows that surgical resection seems the treatment of choice for early stage lung cancer. Further studies are required to improve outcome by reducing postoperative morbidity and mortality.

Lung cancer in elderly patients / Venuta, Federico; Diso, Daniele; Onorati, Ilaria; Anile, Marco; Mantovani, Sara; Rendina, Erino A.. - In: JOURNAL OF THORACIC DISEASE. - ISSN 2072-1439. - STAMPA. - 8:Suppl 11(2016), pp. S908-S914. [10.21037/jtd.2016.05.20]

Lung cancer in elderly patients

Venuta, Federico
;
Diso, Daniele;Onorati, Ilaria;Anile, Marco;Mantovani, Sara;Rendina, Erino A.
2016

Abstract

There is a worldwide-accepted evidence of a population shift toward older ages. This shift favors an increased risk of developing lung cancer that is primarily a disease of older populations. Decision making is extremely difficult in elderly patients, since this group is under-represented in clinical trials with only 25% of them historically opening to patients older than 65 years. For all these reasons, a "customized" preoperative assessment to identify physiological or pathological frailty should be encouraged since standard tools may be less reliable. The work already done to improve patient selection for lung surgery in the elderly population clearly shows that surgical resection seems the treatment of choice for early stage lung cancer. Further studies are required to improve outcome by reducing postoperative morbidity and mortality.
2016
Elderly patients; Lung cancer; Lung resection; Pulmonary and Respiratory Medicine
01 Pubblicazione su rivista::01a Articolo in rivista
Lung cancer in elderly patients / Venuta, Federico; Diso, Daniele; Onorati, Ilaria; Anile, Marco; Mantovani, Sara; Rendina, Erino A.. - In: JOURNAL OF THORACIC DISEASE. - ISSN 2072-1439. - STAMPA. - 8:Suppl 11(2016), pp. S908-S914. [10.21037/jtd.2016.05.20]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/1037585
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