[Activity of oral lactoferrin into systematic iron homeostasis in pregnant women suffering from iron deficiency and iron deficiency anemia]

L'abstract è stato pubblicato in bulgaro. La traduzione dal testo inglese è la seguente: Iron is an essential element for living organisms. Its acquisition occurs in the duodenum in which is reduced by reductase and, then, is transported by DMT1 into host cells in whichis sequestered by ferritin. The export of iron is carried out by ferroportin after the new oxidation by haefestin. This mechanism is perturbed by inflammation and, in particular, by IL-6. Recently, lactoferrin, an iron binding glycoprotein, is emerging as an important natural compound able to exert a significant antiinflammatory activity against IL-6 thus restoring iron transport mechanism. The oral administration of 100 mg of lactoferrin two times a day before meals significantly increases the haematological parameters in pregnant women suffering from iron deficiency or iron deficiency anaemia.