Hypertension, diabetes mellitus, and excess cardiovascular risk. Importance of baseline systolic blood pressure

The growing overall evidence indicates that beneficial cardiovascular effects of BP lowering likely depend on baseline SBP. However, this is not simple because this relationship may differ depending on different subsets of patients. Further stratification studies with deeply phenotyped patients will likely reveal different ideal BP targets for specific subsets of hypertensive patients, including those with diabetes mellitus.