Microsecond pulsed electric fields (μsPEFs) with amplitude of tens of kV/m are used to permeabilize the plasma membrane whereas nanosecond pulsed electric fields of MV/m also permeabilize cell internal structures, such as the endoplasmic reticulum. In this work, a numerical realistic model of cell and its reticulum has been realized to study the use of μsPEFs also for the permeabilization of this internal structure
Microdosimetry for pulsed e fields in a realistic models of cells and endoplasmic reticulum / Denzi, Agnese; Hanna, Hanna; Andre, Franck M.; Mir, Lluis M.; Apollonio, Francesca; Liberti, Micaela. - ELETTRONICO. - (2017), pp. 1-3. (Intervento presentato al convegno 14th International Conference on Synthesis, Modeling, Analysis and Simulation Methods and Applications to Circuit Design, SMACD 2017 tenutosi a Atahotel Naxos Beach Conference Centre, Via Recanati, ita nel 2017) [10.1109/SMACD.2017.7981606].
Microdosimetry for pulsed e fields in a realistic models of cells and endoplasmic reticulum
Denzi, Agnese;Apollonio, Francesca;Liberti, Micaela
2017
Abstract
Microsecond pulsed electric fields (μsPEFs) with amplitude of tens of kV/m are used to permeabilize the plasma membrane whereas nanosecond pulsed electric fields of MV/m also permeabilize cell internal structures, such as the endoplasmic reticulum. In this work, a numerical realistic model of cell and its reticulum has been realized to study the use of μsPEFs also for the permeabilization of this internal structure| File | Dimensione | Formato | |
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