We identified a novel isoform transcript, MPP alpha-2, of the mouse Mg(2+)-dependent protein phosphatase (MPP) alpha gene. The amino acid sequence encoded by MPP alpha-2 differs from the previously known MPP alpha-1 sequence only at the carboxyl terminal region. Northern and in situ hybridization analysis revealed differential expression patterns of these two transcripts in the embryo and in the adult organism, suggesting an elaborate regulation of the MPP alpha gene.
Molecular cloning and expression analysis of MPPa-2, a novel mouse transcript detected in a differential screen of pituitary libraries / Miyamoto, T.; Fiorenza, Maria Teresa; Zhao, Y.; Hasuike, S.; Westphal, H.. - In: BIOCHIMICA ET BIOPHYSICA ACTA. - ISSN 0006-3002. - STAMPA. - 1577:(2002), pp. 109-112. [10.1016/S0167-478(02)00293-2]
Molecular cloning and expression analysis of MPPa-2, a novel mouse transcript detected in a differential screen of pituitary libraries
FIORENZA, Maria Teresa;
2002
Abstract
We identified a novel isoform transcript, MPP alpha-2, of the mouse Mg(2+)-dependent protein phosphatase (MPP) alpha gene. The amino acid sequence encoded by MPP alpha-2 differs from the previously known MPP alpha-1 sequence only at the carboxyl terminal region. Northern and in situ hybridization analysis revealed differential expression patterns of these two transcripts in the embryo and in the adult organism, suggesting an elaborate regulation of the MPP alpha gene.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
