Depression in schizophrenia represents a challenge from a diagnostic, psychopathological and therapeutic perspective. The objective of this study is to test the hypothesis that resilience and self-stigma affect depression severity and to evaluate the strength of their relations in 921 patients with schizophrenia. A structural equation model was tested where depression is hypothesized as affected by resilience, internalized stigma, gender and negative symptoms, with the latter two variables used as exogenous covariates and the former two as mediators. The analysis reveals that low resilience, high negative symptoms, female gender were directly associated with depression severity, and internalized stigma acted only as a mediator between avolition and resilience, with similar magnitude. The cross-sectional study design and the variable selection limit the generalizability of the study results. The model supports a complex interaction between personal resources and negative symptoms in predicting depression in schizophrenia. The clinical implication of these findings is that personal resources could be a significant target of psychosocial treatments.

Personal resources and depression in schizophrenia. The role of self-esteem, resilience and internalized stigma / Rossi, Alessandro; Galderisi, Silvana; Rocca, Paola; Bertolino, Alessandro; Rucci, Paola; Gibertoni, Dino; Stratta, Paolo; Mucci, Armida; Aguglia, Eugenio; Amodeo, Giovanni; Bellomo, Antonello; Caforio, Grazia; Carpiniello, Bernardo; Dell'Osso, Liliana; DI FABIO, Fabio; di Giannantonio, Massimo; Marchesi, Carlo; Monteleone, Palmiero; Montemagni, Cristiana; Oldani, Lucio; Roncone, Rita; Sacchetti, Emilio; Santonastaso, Paolo; Zeppegno, Patrizia; Maj, Mario; Bucci, Paola; Amore, Mario; Brugnoli, Roberto; Siracusano, Alberto; Mancini, Marina. - In: PSYCHIATRY RESEARCH. - ISSN 0165-1781. - STAMPA. - 256:(2017), pp. 359-364. [10.1016/j.psychres.2017.06.079]

Personal resources and depression in schizophrenia. The role of self-esteem, resilience and internalized stigma

di Fabio, Fabio;Bucci, Paola;Amore, Mario;Brugnoli, Roberto;Siracusano, Alberto;Mancini, Marina
2017

Abstract

Depression in schizophrenia represents a challenge from a diagnostic, psychopathological and therapeutic perspective. The objective of this study is to test the hypothesis that resilience and self-stigma affect depression severity and to evaluate the strength of their relations in 921 patients with schizophrenia. A structural equation model was tested where depression is hypothesized as affected by resilience, internalized stigma, gender and negative symptoms, with the latter two variables used as exogenous covariates and the former two as mediators. The analysis reveals that low resilience, high negative symptoms, female gender were directly associated with depression severity, and internalized stigma acted only as a mediator between avolition and resilience, with similar magnitude. The cross-sectional study design and the variable selection limit the generalizability of the study results. The model supports a complex interaction between personal resources and negative symptoms in predicting depression in schizophrenia. The clinical implication of these findings is that personal resources could be a significant target of psychosocial treatments.
2017
psychiatry and mental health; biological psychiatry
01 Pubblicazione su rivista::01a Articolo in rivista
Personal resources and depression in schizophrenia. The role of self-esteem, resilience and internalized stigma / Rossi, Alessandro; Galderisi, Silvana; Rocca, Paola; Bertolino, Alessandro; Rucci, Paola; Gibertoni, Dino; Stratta, Paolo; Mucci, Armida; Aguglia, Eugenio; Amodeo, Giovanni; Bellomo, Antonello; Caforio, Grazia; Carpiniello, Bernardo; Dell'Osso, Liliana; DI FABIO, Fabio; di Giannantonio, Massimo; Marchesi, Carlo; Monteleone, Palmiero; Montemagni, Cristiana; Oldani, Lucio; Roncone, Rita; Sacchetti, Emilio; Santonastaso, Paolo; Zeppegno, Patrizia; Maj, Mario; Bucci, Paola; Amore, Mario; Brugnoli, Roberto; Siracusano, Alberto; Mancini, Marina. - In: PSYCHIATRY RESEARCH. - ISSN 0165-1781. - STAMPA. - 256:(2017), pp. 359-364. [10.1016/j.psychres.2017.06.079]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/1000246
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