DI MARCOTULLIO, LUCIA
 Distribuzione geografica
Continente #
NA - Nord America 2.640
EU - Europa 1.182
AS - Asia 365
AF - Africa 45
SA - Sud America 25
OC - Oceania 13
Continente sconosciuto - Info sul continente non disponibili 1
Totale 4.271
Nazione #
US - Stati Uniti d'America 2.594
IT - Italia 439
CN - Cina 203
FR - Francia 197
DE - Germania 106
GB - Regno Unito 83
CZ - Repubblica Ceca 69
RU - Federazione Russa 53
UA - Ucraina 46
NL - Olanda 44
CA - Canada 38
ZA - Sudafrica 31
JP - Giappone 28
FI - Finlandia 23
SE - Svezia 21
AT - Austria 20
IN - India 20
KR - Corea 20
ES - Italia 17
IE - Irlanda 15
HK - Hong Kong 14
BG - Bulgaria 13
EG - Egitto 13
CL - Cile 12
SG - Singapore 11
TW - Taiwan 11
AU - Australia 10
CH - Svizzera 10
PK - Pakistan 9
TH - Thailandia 9
BR - Brasile 7
ID - Indonesia 7
PL - Polonia 7
IL - Israele 6
MX - Messico 6
TR - Turchia 6
AE - Emirati Arabi Uniti 5
AR - Argentina 5
MY - Malesia 5
RO - Romania 5
BE - Belgio 3
NZ - Nuova Zelanda 3
VN - Vietnam 3
GR - Grecia 2
HR - Croazia 2
BZ - Belize 1
CO - Colombia 1
DK - Danimarca 1
EU - Europa 1
HN - Honduras 1
HU - Ungheria 1
IQ - Iraq 1
IR - Iran 1
JO - Giordania 1
LB - Libano 1
LU - Lussemburgo 1
MA - Marocco 1
MK - Macedonia 1
MO - Macao, regione amministrativa speciale della Cina 1
NO - Norvegia 1
PH - Filippine 1
PS - Palestinian Territory 1
PT - Portogallo 1
QA - Qatar 1
RS - Serbia 1
Totale 4.271
Città #
Fairfield 281
Santa Cruz 266
Rome 241
Ashburn 179
Houston 163
Seattle 154
Buffalo 150
Woodbridge 125
Cambridge 86
Ann Arbor 67
Wilmington 65
Columbus 52
Chicago 43
Des Moines 38
Los Angeles 38
Enfield 34
Las Vegas 34
San Diego 32
Beijing 28
Phoenix 25
Muizenberg 24
Helsinki 21
Wuhan 21
Boardman 18
Frankfurt am Main 16
New York 16
San Jose 16
Shanghai 16
Andover 15
Guangzhou 15
Paris 15
Tokyo 15
Vienna 15
Dublin 14
Siena 14
Toronto 14
Mountain View 13
Sofia 13
Clearwater 12
Dallas 12
Ottawa 12
Provo 12
Riva 12
Shenyang 12
Amsterdam 11
Bremen 11
Chambéry 11
Stockholm 11
Hangzhou 10
Lake Forest 10
Absecon 9
Council Bluffs 8
Henderson 8
Central 7
London 7
Nanjing 7
Nice 7
Parsippany 7
Alexandria 6
Bangkok 6
Bengaluru 6
Cardiff 6
Chiampo 6
Florence 6
Milan 6
Silverton 6
Singapore 6
Taipei 6
Trieste 6
University Park 6
West Hartford 6
Austin 5
Büdelsdorf 5
Chengdu 5
Herndon 5
San Francisco 5
Turin 5
Atlanta 4
Avezzano 4
Barak 4
Boston 4
Cluj-Napoca 4
Farmington 4
Kuala Lumpur 4
L'aquila 4
Le Bourget-du-Lac 4
Miami 4
Milpitas 4
Montreal 4
Saint Petersburg 4
Sant Cugat del Vallès 4
Scranton 4
Seoul 4
Sunnyvale 4
Yellow Springs 4
Auckland 3
Belfast 3
Berlin 3
Bologna 3
Casilda 3
Totale 2.783
Nome #
Targeting GLI factors to inhibit the Hedgehog pathway, file e3835314-c0cb-15e8-e053-a505fe0a3de9 412
New Indole Tubulin Assembly Inhibitors Cause Stable Arrest of Mitotic Progression, Enhanced Stimulation of Natural Killer Cell Cytotoxic Activity, and Repression of Hedgehog-Dependent Cancer, file e3835314-1399-15e8-e053-a505fe0a3de9 375
Synergistic inhibition of the Hedgehog pathway by newly designed Smo and Gli antagonists bearing the isoflavone scaffold, file e383531b-2db6-15e8-e053-a505fe0a3de9 334
Nutlin-3a enhances natural killer cell-mediated killing of neuroblastoma by restoring p53-dependent expression of ligands for NKG2D and DNAM-1 receptors, file e3835328-e248-15e8-e053-a505fe0a3de9 199
Inhibition of Hedgehog-dependent tumors and cancer stem cells by a newly identified naturally occurring chemotype, file e3835315-822b-15e8-e053-a505fe0a3de9 198
ERAP1 promotes Hedgehog-dependent tumorigenesis by controlling USP47-mediated degradation of βTrCP, file e3835322-c3c6-15e8-e053-a505fe0a3de9 185
1H-NMR metabolomics reveals the Glabrescione B exacerbation of glycolytic metabolism beside the cell growth inhibitory effect in glioma, file e3835324-64ee-15e8-e053-a505fe0a3de9 131
The MRN complex is transcriptionally regulated by MYCN during neural cell proliferation to control replication stress, file e3835313-1a0a-15e8-e053-a505fe0a3de9 130
Targeting hedgehog signalling through the ubiquitylation process: the multiple roles of the HECT-E3 ligase itch, file e3835323-769c-15e8-e053-a505fe0a3de9 130
β-arrestin1-mediated acetylation of Gli1 regulates Hedgehog/Gli signaling and modulates self-renewal of SHH medulloblastoma cancer stem cells, file e3835318-cb1c-15e8-e053-a505fe0a3de9 127
Itch/β-arrestin2-dependent non-proteolytic ubiquitylation of SuFu controls Hedgehog signalling and medulloblastoma tumorigenesis, file e3835319-da54-15e8-e053-a505fe0a3de9 125
Noncanonical GLI1 signaling promotes stemness features and in vivo growth in lung adenocarcinoma, file e383531d-1dc5-15e8-e053-a505fe0a3de9 123
The rna-binding ubiquitin ligase mex3a affects glioblastoma tumorigenesis by inducing ubiquitylation and degradation of rig-i, file e3835325-7705-15e8-e053-a505fe0a3de9 122
The energy sensor AMPK regulates Hedgehog signaling in human cells through a unique Gli1 metabolic checkpoint, file e3835314-8184-15e8-e053-a505fe0a3de9 115
Selective targeting of HDAC1/2 elicits anticancer effects through Gli1 acetylation in preclinical models of SHH Medulloblastoma., file e3835317-00e2-15e8-e053-a505fe0a3de9 114
A Smo/Gli multitarget hedgehog pathway inhibitor impairs tumor growth, file e3835323-769e-15e8-e053-a505fe0a3de9 113
SCF (Fbxl17) ubiquitylation of Sufu regulates Hedgehog signaling and medulloblastoma development, file e3835316-0bc3-15e8-e053-a505fe0a3de9 108
MRE11 inhibition highlights a replication stress-dependent vulnerability of MYCN-driven tumors, file e383531e-6ac9-15e8-e053-a505fe0a3de9 100
KCTD15 inhibits the Hedgehog pathway in Medulloblastoma cells by increasing protein levels of the oncosuppressor KCASH2, file e3835323-f6cd-15e8-e053-a505fe0a3de9 92
Maml1 acts cooperatively with Gli proteins to regulate Sonic hedgheog signaling pathway, file e3835319-b04f-15e8-e053-a505fe0a3de9 90
Discovery, characterization and potential roles of a novel NF-YAx splice variant in human neuroblastoma, file e3835324-739d-15e8-e053-a505fe0a3de9 89
Phenformin inhibits hedgehog-dependent tumor growth through a complex i-independent redox/corepressor module, file e3835324-ff9f-15e8-e053-a505fe0a3de9 79
The SHH/GLI signaling pathway: a therapeutic target for medulloblastoma, file e383532c-84ab-15e8-e053-a505fe0a3de9 75
Gli1/DNA interaction is a druggable target for Hedgehog-dependent tumors, file e3835312-4876-15e8-e053-a505fe0a3de9 70
Glabrescione B delivery by self-assembling micelles efficiently inhibits tumor growth in preclinical models of Hedgehog-dependent medulloblastoma, file e3835328-eb23-15e8-e053-a505fe0a3de9 67
Turning off the switch in medulloblastoma. The inhibitory acetylation of an oncogene, file e3835324-5470-15e8-e053-a505fe0a3de9 65
MK-4101 - a potent inhibitor of the hedgehog pathway - is highly active against medulloblastoma and basal cell carcinoma, file e3835326-7f81-15e8-e053-a505fe0a3de9 62
Downregulation of miR-326 and its host gene β-arrestin1 induces pro survival activity of E2F1 and promotes medulloblastoma growth, file e3835328-06b7-15e8-e053-a505fe0a3de9 61
Mitogen-activated kinase kinase kinase 1 inhibits hedgehog signaling and medulloblastoma growth through GLI1 phosphorylation, file e383532b-9064-15e8-e053-a505fe0a3de9 53
Nuclear Factor of Activated T Cells-dependent Down-regulation of the Transcription Factor Glioma-associated Protein 1 (GLI1) Underlies the Growth Inhibitory Properties of Arachidonic Acid, file e3835315-bc09-15e8-e053-a505fe0a3de9 49
Downregulation of miR-326 and its host gene β-arrestin1 induces pro survival activity of E2F1 and promotes medulloblastoma growth, file e3835329-18da-15e8-e053-a505fe0a3de9 49
Dual smo/braf inhibition by flavonolignans from silybum marianum, file e383532c-a42d-15e8-e053-a505fe0a3de9 48
Cullin3-BTB interface: a novel target for stapled peptides, file e383532e-408a-15e8-e053-a505fe0a3de9 47
Blockade of EIF5A hypusination limits colorectal cancer growth by inhibiting MYC elongation, file e3835329-0a3c-15e8-e053-a505fe0a3de9 44
KCTD1 is a new modulator of the KCASH family of Hedgehog suppressors, file 651d9fb0-22fa-4ca1-930e-28313e7c01b2 37
Corrigendum: Selective targeting of HDAC1/2 elicits anticancer effects through Gli1 acetylation in preclinical models of SHH Medulloblastoma, file e383532d-87ba-15e8-e053-a505fe0a3de9 35
A new smoothened antagonist bearing the purine scaffold shows antitumour activity in vitro and in vivo, file e383532d-f711-15e8-e053-a505fe0a3de9 22
Dubs activating the hedgehog signaling pathway: a promising therapeutic target in cancer, file e383532c-93fc-15e8-e053-a505fe0a3de9 21
Design and synthesis of new withaferin A inspired hedgehog pathway inhibitors, file e383532e-9365-15e8-e053-a505fe0a3de9 20
Drug delivery systems for hedgehog inhibitors in the treatment of SHH-medulloblastoma, file e383532e-520c-15e8-e053-a505fe0a3de9 18
SMA-miRs (MiR-181a- 5p, -324-5p, and -451a) are overexpressed in spinal muscular atrophy skeletal muscle and serum samples, file e383532e-520b-15e8-e053-a505fe0a3de9 17
Harnessing the activation of RIG-I like receptors to inhibit glioblastoma tumorigenesis, file e383532e-970e-15e8-e053-a505fe0a3de9 16
ERAP1 as an emerging therapeutic target for medulloblastoma, file e383532d-f70e-15e8-e053-a505fe0a3de9 13
Thrombospondin-1 is a mediator of the neurotypic differentiation induced by EGF in thymic epithelial cells, file e3835311-9ed0-15e8-e053-a505fe0a3de9 6
Design, palladium-catalyzed synthesis, and biological investigation of 2-substituted 3-aroylquinolin-4(1H)-ones as inhibitors of the Hedgehog signaling pathway., file e383531d-c1a3-15e8-e053-a505fe0a3de9 6
Kras/ADAM17-dependent Jag1-ICD reverse signalling sustains CRC progression and chemoresistance, file e3835323-5f7e-15e8-e053-a505fe0a3de9 6
Combined inhibition of polyamine metabolism and eIF5A hypusination suppresses colorectal cancer growth through a converging effect on MYC translation, file 96008b0d-a210-45cd-b987-beb49d2248bd 4
Chemical, computational and functional insights into the chemical stability of the Hedgehog pathway inhibitor GANT61, file d26acd5c-3127-444f-b143-51c8ec31320d 4
Hedgehog signaling pathway inhibitors: an updated patent review (2015–present), file e3835325-7707-15e8-e053-a505fe0a3de9 4
Synergistic inhibition of the Hedgehog pathway by newly designed Smo and Gli antagonists bearing the isoflavone scaffold, file e383532c-8b2d-15e8-e053-a505fe0a3de9 4
Hedgehog controls neural stem cells through p53-independent regulation of Nanog, file e3835311-7577-15e8-e053-a505fe0a3de9 3
Non-canonical Hedgehog/ampk-mediated control of polyamine metabolism supports neuronal and medulloblastoma cell growth, file e3835313-2cdf-15e8-e053-a505fe0a3de9 3
CNBP regulates wing development in Drosophila melanogaster by promoting IRES-dependent translation of dMyc, file e3835313-ba49-15e8-e053-a505fe0a3de9 3
Exploring the potential of anthraquinone-based hybrids for  identifying a novel generation of antagonists for the Smoothened receptor in HH-dependent tumour, file db979285-ff8c-4b0c-8812-33f7653c5d1a 2
Digging a hole under Hedgehog: Downstream inhibition as an emerging anticancer strategy, file e3835313-2d59-15e8-e053-a505fe0a3de9 2
Insights into gli factors ubiquitylation methods, file e3835314-c6cd-15e8-e053-a505fe0a3de9 2
Hypomorphic Recessive Variants in SUFU Impair the Sonic Hedgehog Pathway and Cause Joubert Syndrome with Cranio-facial and Skeletal Defects, file e3835319-da55-15e8-e053-a505fe0a3de9 2
P300/CBP-associated factor regulates transcription and function of isocitrate dehydrogenase 2 during muscle differentiation, file e3835322-3dbc-15e8-e053-a505fe0a3de9 2
Kras/ADAM17-dependent Jag1-ICD reverse signalling sustains CRC progression and chemoresistance, file e383532a-72dd-15e8-e053-a505fe0a3de9 2
Synergistic inhibition of the Hedgehog pathway by newly designed Smo and Gli antagonists bearing the isoflavone scaffold, file e383532c-9839-15e8-e053-a505fe0a3de9 2
Proteolysis-Targeting Chimera (PROTAC): Is the Technology Looking at the Treatment of Brain Tumors?, file e383532e-b463-15e8-e053-a505fe0a3de9 2
SALL4 is a CRL3^REN/KCTD11 substrate that drives Sonic Hedgehog-dependent medulloblastoma, file 87ae5f63-35f2-48df-bd8d-0e1042b1706d 1
MicroRNA profiling in human medulloblastoma, file e3835311-882a-15e8-e053-a505fe0a3de9 1
Numb is a suppressor of Hedgehog signalling and targets Gli1 for Itch- dependent ubiquitination, file e3835311-a952-15e8-e053-a505fe0a3de9 1
Concerted microRNA control of Hedgehog signalling in cerebellar neuronal progenitor and tumour cells, file e3835311-c35b-15e8-e053-a505fe0a3de9 1
The interplay between microRNAs and the neurotrophin receptor tropomyosin-related kinase C controls proliferation of human neuroblastoma cells, file e3835311-c92f-15e8-e053-a505fe0a3de9 1
PCAF ubiquitin ligase activity inhibits Hedgehog/Gli1 signaling in p53-dependent response to genotoxic stress, file e3835311-d214-15e8-e053-a505fe0a3de9 1
Hedgehog antagonist REN(KCTD11) regulates proliferation and apoptosis of developing granule cell progenitors., file e3835312-24d3-15e8-e053-a505fe0a3de9 1
A gene dosage‐dependent effect unveils NBS1 as both a haploinsufficient tumour suppressor and an essential gene for SHH‐medulloblastoma, file ec134b19-e8bc-4159-83c3-233c964baab9 1
Totale 4.447
Categoria #
all - tutte 9.870
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 9.870


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2018/2019141 0 0 0 0 0 0 0 0 0 0 73 68
2019/2020682 51 40 28 37 61 47 69 84 92 67 49 57
2020/2021756 42 70 35 40 58 44 73 44 97 133 93 27
2021/20221.131 67 54 79 84 95 42 52 79 77 66 315 121
2022/2023968 61 54 247 145 48 86 58 32 24 50 138 25
2023/2024676 32 34 73 49 123 72 58 83 31 32 89 0
Totale 4.447