CONTESTABILE, Roberto
CONTESTABILE, Roberto
DIPARTIMENTO DI SCIENZE BIOCHIMICHE "ALESSANDRO ROSSI FANELLI"
4'-Deoxypyridoxine disrupts vitamin B6 homeostasis in Escherichia coli K12 through combined inhibition of cumulative B6 uptake and PLP-dependent enzyme activity
2023 Babor, Jill; Tramonti, Angela; Nardella, Caterina; Deutschbauer, Adam; Contestabile, Roberto; de Crécy-Lagard, Valérie
A BIOINFORMATIC APPROACH TO THE STUDY OF THE MECHANISM OF ACTION OF SERINE HYDROXYMETHYLTRANSFERASE
1993 Angelaccio, Sebastiana; Pascarella, Stefano; Iurescia, Sandra; delle Fratte, Sonia; Contestabile, Roberto; Bossa, Francesco; Schirch, Verne
A bioinformatics analysis reveals a group of MocR bacterial transcriptional regulators linked to a family of genes coding for membrane proteins
2016 Milano, Teresa; Angelaccio, Sebastiana; Tramonti, Angela; DI SALVO, Martino Luigi; Contestabile, Roberto; Pascarella, Stefano
A comprehensive computational analysis of Mycobacterium genomes pinpoints the genes co-occurring with ycze, a membrane protein coding gene under the putative control of a mocr, and predicts its function
2018 Milano, Teresa; Angelaccio, Sebastiana; Tramonti, Angela; DI SALVO, Martino Luigi; Nogues, Isabel; Contestabile, Roberto; Pascarella, Stefano
A gene-nutrient interaction between vitamin B6 and serine hydroxymethyltransferase (SHMT) affects genome integrity in Drosophila
2023 Pilesi, Eleonora; Angioli, Chiara; Graziani, Claudio; Parroni, Alessia; Contestabile, Roberto; Tramonti, Angela; Verni', Fiammetta
A novel, easy assay method for human cysteine sulfinic acid decarboxylase
2021 Tramonti, A.; Contestabile, R.; Florio, R.; Nardella, C.; Barile, A.; Di Salvo, M. L.
A pyrazolopyran derivative preferentially inhibits the activity of human cytosolic hydroxymethyltransferase and induces cell death in lung cancer cells
2016 Marani, Marina; Paone, Alessio; Fiascarelli, Alessio; Macone, Alberto; Gargano, Maurizio; Rinaldo, Serena; Giardina, Giorgio; Pontecorvi, Valentino; Koes, David; Mcdermott, Lee; Yang, Tianyi; Paiardini, Alessandro; Contestabile, Roberto; Cutruzzola, Francesca
Alanine racemase from Tolypocladium inflatum: A key PLP-dependent enzyme in cyclosporin biosynthesis and a model of catalytic promiscuity
2013 DI SALVO, Martino Luigi; Florio, Rita; Paiardini, Alessandro; Vivoli, Mirella; Simona, D'Aguanno; Contestabile, Roberto
Allosteric feedback inhibition of pyridoxine 5'-phosphate oxidase from escherichia coli
2019 Barile, A.; Tramonti, A.; Di Salvo, M. L.; Nogues, I.; Nardella, C.; Malatesta, F.; Contestabile, R.
An engineered escherichia coli strain with synthetic metabolism for in‐cell production of translationally active methionine derivatives
2020 Schipp, Christian Johannes; Ma, Ying; Al‐shameri, Ammar; D'Alessio, Federico; Neubauer, Peter; Contestabile, Roberto; Budisa, Nediljko; Di Salvo, Martino Luigi
Arabidopsis thaliana serine hydroxymethyltransferases: functions, structures, and perspectives
2022 Nogués, Isabel; Sekula, Bartosz; Angelaccio, Sebastiana; Grzechowiak, Marta; Tramonti, Angela; Contestabile, Roberto; Ruszkowski, Milosz
Asymmetry of the Active Site Loop Conformation between Subunits of Glutamate-1-semialdehyde Aminomutase in Solution
2013 Barbara, Campanini; Stefano, Bettati; DI SALVO, Martino Luigi; Andrea, Mozzarelli; Contestabile, Roberto
Biochemical data from the characterization of a new pathogenic mutation of human pyridoxine-5'-phosphate oxidase (PNPO)
2017 Di Salvo, Martino L.; Mastrangelo, Mario; Nogués, Isabel; Tolve, Manuela; Paiardini, Alessandro; Carducci, Carla; Mei, Davide; Montomoli, Martino; Tramonti, Angela; Guerrini, Renzo; Contestabile, Roberto; Leuzzi, Vincenzo
BIOCHIMICA per Studenti di Scienze della Vita
2007 W., MULLER ESTERL; DI SALVO, Martino Luigi; Contestabile, Roberto
Biomedical aspects of pyridoxal 5’-phosphate availability
2012 DI SALVO, Martino Luigi; Safo, Mk; Contestabile, Roberto
Catalytic and thermodynamic properties of tetrahydromethanopterin-dependent serine hydroxymethyltransferase from Methanococcus jannaschii.
2003 Angelaccio, Sebastiana; Chiaraluce, Roberta; Consalvi, Valerio; Buchenau, B; Giangiacomo, L; Bossa, Francesco; Contestabile, Roberto
Characterization of novel pathogenic variants causing pyridox(Am)ine 5′-phosphate oxidase-dependent epilepsy
2021 Barile, A.; Mills, P.; Di Salvo, M. L.; Graziani, C.; Bunik, V.; Clayton, P.; Contestabile, R.; Tramonti, A.
Characterization of the Escherichia coli pyridoxal 5'-phosphate homeostasis protein (YggS): Role of lysine residues in PLP binding and protein stability
2022 Tramonti, Angela; Ghatge, Mohini S; Babor, Jill T; Musayev, Faik N; di Salvo, Martino Luigi; Barile, Anna; Colotti, Gianni; Giorgi, Alessandra; Paredes, Steven D; Donkor, Akua K; Al Mughram, Mohammed H; de Crécy-Lagard, Valérie; Safo, Martin K; Contestabile, Roberto
COMUNICAZIONE ORALE A CONGRESSO “The contribution of a conformationally-mobile, active-site loop to the reaction catalysed by glutamate semialdehyde aminomutase”, in the 2nd International Symposium on Vitamin B6, PQQ, Carbonyl Catalysis and Quinoproteins, Santa Fe, New Mexico, U.S.A., 31 October- 5 November 1999.
1999 Contestabile, Roberto; John, Ra
COMUNICAZIONE ORALE A CONGRESSO SU INVITO “Asymmetric reactivity of glutamate semialdehyde aminomutase with cyanoborohydride” in the European meeting on pyridoxal phosphate-dependent enzymes, Basel, Switzerland, 20-23 September 1997.
1997 Contestabile, Roberto; John, Ra
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| 4'-Deoxypyridoxine disrupts vitamin B6 homeostasis in Escherichia coli K12 through combined inhibition of cumulative B6 uptake and PLP-dependent enzyme activity | 2023 | Babor, Jill; Tramonti, Angela; Nardella, Caterina; Deutschbauer, Adam; Contestabile, Roberto; de Crécy-Lagard, Valérie | |
| A BIOINFORMATIC APPROACH TO THE STUDY OF THE MECHANISM OF ACTION OF SERINE HYDROXYMETHYLTRANSFERASE | 1993 | Angelaccio, Sebastiana; Pascarella, Stefano; Iurescia, Sandra; delle Fratte, Sonia; Contestabile, Roberto; Bossa, Francesco; Schirch, Verne | |
| A bioinformatics analysis reveals a group of MocR bacterial transcriptional regulators linked to a family of genes coding for membrane proteins | 2016 | Milano, Teresa; Angelaccio, Sebastiana; Tramonti, Angela; DI SALVO, Martino Luigi; Contestabile, Roberto; Pascarella, Stefano | |
| A comprehensive computational analysis of Mycobacterium genomes pinpoints the genes co-occurring with ycze, a membrane protein coding gene under the putative control of a mocr, and predicts its function | 2018 | Milano, Teresa; Angelaccio, Sebastiana; Tramonti, Angela; DI SALVO, Martino Luigi; Nogues, Isabel; Contestabile, Roberto; Pascarella, Stefano | |
| A gene-nutrient interaction between vitamin B6 and serine hydroxymethyltransferase (SHMT) affects genome integrity in Drosophila | 2023 | Pilesi, Eleonora; Angioli, Chiara; Graziani, Claudio; Parroni, Alessia; Contestabile, Roberto; Tramonti, Angela; Verni', Fiammetta | |
| A novel, easy assay method for human cysteine sulfinic acid decarboxylase | 2021 | Tramonti, A.; Contestabile, R.; Florio, R.; Nardella, C.; Barile, A.; Di Salvo, M. L. | |
| A pyrazolopyran derivative preferentially inhibits the activity of human cytosolic hydroxymethyltransferase and induces cell death in lung cancer cells | 2016 | Marani, Marina; Paone, Alessio; Fiascarelli, Alessio; Macone, Alberto; Gargano, Maurizio; Rinaldo, Serena; Giardina, Giorgio; Pontecorvi, Valentino; Koes, David; Mcdermott, Lee; Yang, Tianyi; Paiardini, Alessandro; Contestabile, Roberto; Cutruzzola, Francesca | |
| Alanine racemase from Tolypocladium inflatum: A key PLP-dependent enzyme in cyclosporin biosynthesis and a model of catalytic promiscuity | 2013 | DI SALVO, Martino Luigi; Florio, Rita; Paiardini, Alessandro; Vivoli, Mirella; Simona, D'Aguanno; Contestabile, Roberto | |
| Allosteric feedback inhibition of pyridoxine 5'-phosphate oxidase from escherichia coli | 2019 | Barile, A.; Tramonti, A.; Di Salvo, M. L.; Nogues, I.; Nardella, C.; Malatesta, F.; Contestabile, R. | |
| An engineered escherichia coli strain with synthetic metabolism for in‐cell production of translationally active methionine derivatives | 2020 | Schipp, Christian Johannes; Ma, Ying; Al‐shameri, Ammar; D'Alessio, Federico; Neubauer, Peter; Contestabile, Roberto; Budisa, Nediljko; Di Salvo, Martino Luigi | |
| Arabidopsis thaliana serine hydroxymethyltransferases: functions, structures, and perspectives | 2022 | Nogués, Isabel; Sekula, Bartosz; Angelaccio, Sebastiana; Grzechowiak, Marta; Tramonti, Angela; Contestabile, Roberto; Ruszkowski, Milosz | |
| Asymmetry of the Active Site Loop Conformation between Subunits of Glutamate-1-semialdehyde Aminomutase in Solution | 2013 | Barbara, Campanini; Stefano, Bettati; DI SALVO, Martino Luigi; Andrea, Mozzarelli; Contestabile, Roberto | |
| Biochemical data from the characterization of a new pathogenic mutation of human pyridoxine-5'-phosphate oxidase (PNPO) | 2017 | Di Salvo, Martino L.; Mastrangelo, Mario; Nogués, Isabel; Tolve, Manuela; Paiardini, Alessandro; Carducci, Carla; Mei, Davide; Montomoli, Martino; Tramonti, Angela; Guerrini, Renzo; Contestabile, Roberto; Leuzzi, Vincenzo | |
| BIOCHIMICA per Studenti di Scienze della Vita | 2007 | W., MULLER ESTERL; DI SALVO, Martino Luigi; Contestabile, Roberto | |
| Biomedical aspects of pyridoxal 5’-phosphate availability | 2012 | DI SALVO, Martino Luigi; Safo, Mk; Contestabile, Roberto | |
| Catalytic and thermodynamic properties of tetrahydromethanopterin-dependent serine hydroxymethyltransferase from Methanococcus jannaschii. | 2003 | Angelaccio, Sebastiana; Chiaraluce, Roberta; Consalvi, Valerio; Buchenau, B; Giangiacomo, L; Bossa, Francesco; Contestabile, Roberto | |
| Characterization of novel pathogenic variants causing pyridox(Am)ine 5′-phosphate oxidase-dependent epilepsy | 2021 | Barile, A.; Mills, P.; Di Salvo, M. L.; Graziani, C.; Bunik, V.; Clayton, P.; Contestabile, R.; Tramonti, A. | |
| Characterization of the Escherichia coli pyridoxal 5'-phosphate homeostasis protein (YggS): Role of lysine residues in PLP binding and protein stability | 2022 | Tramonti, Angela; Ghatge, Mohini S; Babor, Jill T; Musayev, Faik N; di Salvo, Martino Luigi; Barile, Anna; Colotti, Gianni; Giorgi, Alessandra; Paredes, Steven D; Donkor, Akua K; Al Mughram, Mohammed H; de Crécy-Lagard, Valérie; Safo, Martin K; Contestabile, Roberto | |
| COMUNICAZIONE ORALE A CONGRESSO “The contribution of a conformationally-mobile, active-site loop to the reaction catalysed by glutamate semialdehyde aminomutase”, in the 2nd International Symposium on Vitamin B6, PQQ, Carbonyl Catalysis and Quinoproteins, Santa Fe, New Mexico, U.S.A., 31 October- 5 November 1999. | 1999 | Contestabile, Roberto; John, Ra | |
| COMUNICAZIONE ORALE A CONGRESSO SU INVITO “Asymmetric reactivity of glutamate semialdehyde aminomutase with cyanoborohydride” in the European meeting on pyridoxal phosphate-dependent enzymes, Basel, Switzerland, 20-23 September 1997. | 1997 | Contestabile, Roberto; John, Ra |