VALENTE, Sergio
VALENTE, Sergio
DIPARTIMENTO DI CHIMICA E TECNOLOGIE DEL FARMACO
1,3,4-Oxadiazole-Containing Histone Deacetylase Inhibitors: Anticancer Activities in Cancer Cells
2014 Valente, Sergio; D., Trisciuoglio; T., De Luca; A., Nebbioso; Labella, Donatella; Lenoci, Alessia; C., Bigogno; G. M., Dondio; M., Miceli; G., Brosch; D., Del Bufalo; L., Altucci; Mai, Antonello
1,4-Dihydropyridines Active on the SIRT1/AMPK Pathway Ameliorate Skin Repair and Mitochondrial Function and Exhibit Inhibition of Proliferation in Cancer Cells
2016 Valente, Sergio; Mellini, Paolo; Spallotta, Francesco; Carafa, Vincenzo; Nebbioso, Angela; Polletta, Lucia; Carnevale, Ilaria; Saladini, Serena; Trisciuoglio, Daniela; Gabellini, Chiara; Tardugno, Maria; Zwergel, Clemens; Cencioni, Chiara; Atlante, Sandra; Moniot, Sébastien; Steegborn, Clemens; Budriesi, Roberta; Tafani, Marco; Del Bufalo, Donatella; Altucci, Lucia; Gaetano, Carlo; Mai, Antonello
3-(1H-pyrrol-2- and –3-yl)-2-oxazolidinones as novel potent and selective monoamine oxidase type A inhibitors.
2003 Mai, Antonello; I., Cervara; Valente, Sergio; Artico, Marino; G., Sbardella; Befani, Olivia; Turini, Paola; Agostinelli, Enzo
3-(1H-pyrrol-2- and –3-yl)-2-oxazolidinones as novel potent and selective monoamine oxidase type A inhibitors.
2003 Mai, Antonello; Cervara, I.; Valente, Sergio; Artico, Marino; Sbardella, G.; Befani, Olivia; Turini, Paola; Agostinelli, Enzo
3-(1H-Pyrrol-2-yl)-2-oxazolidinones as novel monoamine oxidase type A inhibitors.
2005 Mai, A; Artico, M.; Valente, S; Sbardella, G; Turini, P; Befani, O; DALLA VEDOVA, L; Agostinelli, E
3-(4-Aroyl-1-methyl-1H-2-pyrrolyl)-N-hydroxy-2-propenamides as a New Class of Synthetic Histone Deacetylase Inhibitors. 2. Effect of Pyrrole-C2 and/or -C4 Substitutions on Biological Activity
2004 Mai, Antonello; S., Massa; I., Cerbara; Valente, Sergio; Ragno, Rino; P., Bottoni; R., Scatena; P., Loidl; G., Brosch
3-(4-Aroyl-1-methyl-1H-pyrrol-2-yl)-N-hydroxy-2-propenamides as a new class of synthetic histone deacetylase inhibitors. 3. Discovery of novel lead compounds through structure-based drug design and docking studies.
2004 Ragno, Rino; Mai, Antonello; Massa, S; Cerbara, I; Valente, Sergio; Bottoni, P; Scatena, R; Jesacher, F; Loidl, P; Brosch, G.
3-D QSAR Studies on Histone Deacetylase Inhibitors. A GOLPE/GRID Approach on Different Series of Compounds.
2006 Ragno, Rino; Simeoni, S; Valente, Sergio; Massa, S; Mai, Antonello
A closer look into NADPH oxidase inhibitors: validation and insight into their mechanism of action
2020 Reis, J.; Massari, M.; Marchese, S.; Ceccon, M.; Aalbers, F. S.; Corana, F.; Valente, S.; Mai, A.; Magnani, F.; Mattevi, A.
A Nitric Oxide-dependent crosstalk between class I and III Histone Deacetylases accelerates skin repair.
2013 2. Spallotta, F.; Cencioni, C.; Straino, S.; Nanni, S.; Rosati, J.; Artuso, S.; Manni, I.; Colussi, C.; Piaggio, G.; Martelli, F.; Valente, Sergio; Mai, Antonello; Capogrossi, M. C.; Farsetti, A.; Gaetano, C.
A novel coumarin-quinone derivative SV37 inhibits CDC25 phosphatases, impairs proliferation, and induces cell death.
2013 Emilie, Bana; Sibille, Estelle; Valente, Sergio; Claudia, Cerella; Patrick, Chaimbault; Kirsch, Gilbert; Mario, Dicato; Marc, Diederich; Denyse, Bagrel
A quinoline-based DNA methyltransferase inhibitor as a possible adjuvant in osteosarcoma therapy
2018 Manara, Maria Cristina; Valente, Sergio; Cristalli, Camilla; Nicoletti, Giordano; Landuzzi, Lorena; Zwergel, Clemens; Mazzone, Roberta; Stazi, Giulia; Arimondo, Paola B.; Pasello, Michela; Guerzoni, Clara; Picci, Piero; Nanni, Patrizia; Lollini, Pier-Luigi; Mai, Antonello; Scotlandi, Katia
Abstract 2946: Effects of two novel quinoline-based non-nucleoside DNA methyltransferase inhibitors against bone sarcomas
2015 Manara, Maria Cristina; Valente, Sergio; Cristalli, Camilla; Baricordi, Cristina; Zwergel, Clemens; Arimondo, Paola B; Picci, Piero; Mai, Antonello; Scotlandi, Katia
Altered mitochondrial function in cells carrying a premutation or unmethylated full mutation of the FMR1 gene
2020 Nobile, V.; Palumbo, F.; Lanni, S.; Ghisio, V.; Vitali, A.; Castagnola, M.; Marzano, V.; Maulucci, G.; De Angelis, C.; De Spirito, M.; Pacini, L.; D'Andrea, L.; Ragno, R.; Stazi, G.; Valente, S.; Mai, A.; Chiurazzi, P.; Genuardi, M.; Neri, G.; Tabolacci, E.
Altered modulation of lamin A/C-HDAC2 interaction and p21 expression during oxidative stress response in HGPS
2018 Mattioli, Elisabetta; Andrenacci, Davide; Garofalo, Cecilia; Prencipe, Sabino; Scotlandi, Katia; Remondini, Daniel; Gentilini, Davide; Di Blasio, Anna Maria; Valente, Sergio; Scarano, Emanuela; Cicchilitti, Lucia; Piaggio, Giulia; Mai, Antonello; Lattanzi, Giovanna
Amino acid starvation induces reactivation of silenced transgenes and latent HIV-1 provirus via down-regulation of histone deacetylase 4 (HDAC4)
2012 I., Palmisano; G., Della Chiara; R. L., D'Ambrosio; C., Huichalaf; P., Brambilla; S., Corbetta; M., Riba; R., Piccirillo; Valente, Sergio; G., Casari; Mai, Antonello; F., Martinelli Boneschi; D., Gabellini; G., Poli; M. V., Schiaffino
Antimalarial and Antileishmanial Activities of Aroyl-pyrrolyl-hydroxy-amides, a New Class of Histone Deacetylase Inhibitors
2004 Mai, Antonello; I., Cerbara; Valente, Sergio; S., Massa; L. A., Walker; B. L., Tekwani
Application of 3 μm particle-based amylose-derived chiral stationary phases for the enantioseparation of potential histone deacetylase inhibitors.
2011 Ferretti, R; Mai, Antonello; Gallinella, B; Zanitti, L; Valente, Sergio; Cirilli, R.
Application of small epigenetic modulators in pediatric medulloblastoma
2018 Zwergel, Clemens; Romanelli, Annalisa; Stazi, Giulia; Besharat, Zein Mersini; Catanzaro, Giuseppina; Tafani, Marco; Valente, Sergio; Mai, Antonello
Aroyl-pyrrolyl hydroxyamides: Influence of pyrrole C4-phenylacetyl substitution on histone deacetylase inhibition
2006 Mai, Antonello; Silvio, Massa; Valente, Sergio; Silvia, Simeoni; Ragno, Rino; Patrizia, Bottoni; Roberto, Scatena; Gerald, Brosch
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| 1,3,4-Oxadiazole-Containing Histone Deacetylase Inhibitors: Anticancer Activities in Cancer Cells | 2014 | Valente, Sergio; D., Trisciuoglio; T., De Luca; A., Nebbioso; Labella, Donatella; Lenoci, Alessia; C., Bigogno; G. M., Dondio; M., Miceli; G., Brosch; D., Del Bufalo; L., Altucci; Mai, Antonello | |
| 1,4-Dihydropyridines Active on the SIRT1/AMPK Pathway Ameliorate Skin Repair and Mitochondrial Function and Exhibit Inhibition of Proliferation in Cancer Cells | 2016 | Valente, Sergio; Mellini, Paolo; Spallotta, Francesco; Carafa, Vincenzo; Nebbioso, Angela; Polletta, Lucia; Carnevale, Ilaria; Saladini, Serena; Trisciuoglio, Daniela; Gabellini, Chiara; Tardugno, Maria; Zwergel, Clemens; Cencioni, Chiara; Atlante, Sandra; Moniot, Sébastien; Steegborn, Clemens; Budriesi, Roberta; Tafani, Marco; Del Bufalo, Donatella; Altucci, Lucia; Gaetano, Carlo; Mai, Antonello | |
| 3-(1H-pyrrol-2- and –3-yl)-2-oxazolidinones as novel potent and selective monoamine oxidase type A inhibitors. | 2003 | Mai, Antonello; I., Cervara; Valente, Sergio; Artico, Marino; G., Sbardella; Befani, Olivia; Turini, Paola; Agostinelli, Enzo | |
| 3-(1H-pyrrol-2- and –3-yl)-2-oxazolidinones as novel potent and selective monoamine oxidase type A inhibitors. | 2003 | Mai, Antonello; Cervara, I.; Valente, Sergio; Artico, Marino; Sbardella, G.; Befani, Olivia; Turini, Paola; Agostinelli, Enzo | |
| 3-(1H-Pyrrol-2-yl)-2-oxazolidinones as novel monoamine oxidase type A inhibitors. | 2005 | Mai, A; Artico, M.; Valente, S; Sbardella, G; Turini, P; Befani, O; DALLA VEDOVA, L; Agostinelli, E | |
| 3-(4-Aroyl-1-methyl-1H-2-pyrrolyl)-N-hydroxy-2-propenamides as a New Class of Synthetic Histone Deacetylase Inhibitors. 2. Effect of Pyrrole-C2 and/or -C4 Substitutions on Biological Activity | 2004 | Mai, Antonello; S., Massa; I., Cerbara; Valente, Sergio; Ragno, Rino; P., Bottoni; R., Scatena; P., Loidl; G., Brosch | |
| 3-(4-Aroyl-1-methyl-1H-pyrrol-2-yl)-N-hydroxy-2-propenamides as a new class of synthetic histone deacetylase inhibitors. 3. Discovery of novel lead compounds through structure-based drug design and docking studies. | 2004 | Ragno, Rino; Mai, Antonello; Massa, S; Cerbara, I; Valente, Sergio; Bottoni, P; Scatena, R; Jesacher, F; Loidl, P; Brosch, G. | |
| 3-D QSAR Studies on Histone Deacetylase Inhibitors. A GOLPE/GRID Approach on Different Series of Compounds. | 2006 | Ragno, Rino; Simeoni, S; Valente, Sergio; Massa, S; Mai, Antonello | |
| A closer look into NADPH oxidase inhibitors: validation and insight into their mechanism of action | 2020 | Reis, J.; Massari, M.; Marchese, S.; Ceccon, M.; Aalbers, F. S.; Corana, F.; Valente, S.; Mai, A.; Magnani, F.; Mattevi, A. | |
| A Nitric Oxide-dependent crosstalk between class I and III Histone Deacetylases accelerates skin repair. | 2013 | 2. Spallotta, F.; Cencioni, C.; Straino, S.; Nanni, S.; Rosati, J.; Artuso, S.; Manni, I.; Colussi, C.; Piaggio, G.; Martelli, F.; Valente, Sergio; Mai, Antonello; Capogrossi, M. C.; Farsetti, A.; Gaetano, C. | |
| A novel coumarin-quinone derivative SV37 inhibits CDC25 phosphatases, impairs proliferation, and induces cell death. | 2013 | Emilie, Bana; Sibille, Estelle; Valente, Sergio; Claudia, Cerella; Patrick, Chaimbault; Kirsch, Gilbert; Mario, Dicato; Marc, Diederich; Denyse, Bagrel | |
| A quinoline-based DNA methyltransferase inhibitor as a possible adjuvant in osteosarcoma therapy | 2018 | Manara, Maria Cristina; Valente, Sergio; Cristalli, Camilla; Nicoletti, Giordano; Landuzzi, Lorena; Zwergel, Clemens; Mazzone, Roberta; Stazi, Giulia; Arimondo, Paola B.; Pasello, Michela; Guerzoni, Clara; Picci, Piero; Nanni, Patrizia; Lollini, Pier-Luigi; Mai, Antonello; Scotlandi, Katia | |
| Abstract 2946: Effects of two novel quinoline-based non-nucleoside DNA methyltransferase inhibitors against bone sarcomas | 2015 | Manara, Maria Cristina; Valente, Sergio; Cristalli, Camilla; Baricordi, Cristina; Zwergel, Clemens; Arimondo, Paola B; Picci, Piero; Mai, Antonello; Scotlandi, Katia | |
| Altered mitochondrial function in cells carrying a premutation or unmethylated full mutation of the FMR1 gene | 2020 | Nobile, V.; Palumbo, F.; Lanni, S.; Ghisio, V.; Vitali, A.; Castagnola, M.; Marzano, V.; Maulucci, G.; De Angelis, C.; De Spirito, M.; Pacini, L.; D'Andrea, L.; Ragno, R.; Stazi, G.; Valente, S.; Mai, A.; Chiurazzi, P.; Genuardi, M.; Neri, G.; Tabolacci, E. | |
| Altered modulation of lamin A/C-HDAC2 interaction and p21 expression during oxidative stress response in HGPS | 2018 | Mattioli, Elisabetta; Andrenacci, Davide; Garofalo, Cecilia; Prencipe, Sabino; Scotlandi, Katia; Remondini, Daniel; Gentilini, Davide; Di Blasio, Anna Maria; Valente, Sergio; Scarano, Emanuela; Cicchilitti, Lucia; Piaggio, Giulia; Mai, Antonello; Lattanzi, Giovanna | |
| Amino acid starvation induces reactivation of silenced transgenes and latent HIV-1 provirus via down-regulation of histone deacetylase 4 (HDAC4) | 2012 | I., Palmisano; G., Della Chiara; R. L., D'Ambrosio; C., Huichalaf; P., Brambilla; S., Corbetta; M., Riba; R., Piccirillo; Valente, Sergio; G., Casari; Mai, Antonello; F., Martinelli Boneschi; D., Gabellini; G., Poli; M. V., Schiaffino | |
| Antimalarial and Antileishmanial Activities of Aroyl-pyrrolyl-hydroxy-amides, a New Class of Histone Deacetylase Inhibitors | 2004 | Mai, Antonello; I., Cerbara; Valente, Sergio; S., Massa; L. A., Walker; B. L., Tekwani | |
| Application of 3 μm particle-based amylose-derived chiral stationary phases for the enantioseparation of potential histone deacetylase inhibitors. | 2011 | Ferretti, R; Mai, Antonello; Gallinella, B; Zanitti, L; Valente, Sergio; Cirilli, R. | |
| Application of small epigenetic modulators in pediatric medulloblastoma | 2018 | Zwergel, Clemens; Romanelli, Annalisa; Stazi, Giulia; Besharat, Zein Mersini; Catanzaro, Giuseppina; Tafani, Marco; Valente, Sergio; Mai, Antonello | |
| Aroyl-pyrrolyl hydroxyamides: Influence of pyrrole C4-phenylacetyl substitution on histone deacetylase inhibition | 2006 | Mai, Antonello; Silvio, Massa; Valente, Sergio; Silvia, Simeoni; Ragno, Rino; Patrizia, Bottoni; Roberto, Scatena; Gerald, Brosch |