: Eukaryotes solve the DNA-end replication problem synthesizing hexameric chromosome ends known as telomeres. Recent studies have uncovered unexpected functions of telomeres in linking synaptic signaling and vesicle transport, with at least one pathway directly involved in transferring telomeres through the immune synapse. These emerging forms of cellular communication may originate a new class of antiaging interventions based on telomere transplants.
Detection of Telomere Transfer at Immunological Synapse / Lanna, Alessio; D'Ambra, Clara. - (2023), pp. 251-261. - METHODS IN MOLECULAR BIOLOGY. [10.1007/978-1-0716-3135-5_16].
Detection of Telomere Transfer at Immunological Synapse
D'Ambra, Clara
2023
Abstract
: Eukaryotes solve the DNA-end replication problem synthesizing hexameric chromosome ends known as telomeres. Recent studies have uncovered unexpected functions of telomeres in linking synaptic signaling and vesicle transport, with at least one pathway directly involved in transferring telomeres through the immune synapse. These emerging forms of cellular communication may originate a new class of antiaging interventions based on telomere transplants.File allegati a questo prodotto
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