It happens in Nature that compounds with interesting biological activity are formed of individual blocks of different structures, which are generally active by themselves. For example, different acids such as quinic acid or shikimic acid, are found to be conjugated to caffeic acid. In these cases the combination is the result of a biosynthetic process. At the same time, chemists were interested in melting together natural products known for specific activity in a way to obtain a multiple shot for the biological effect or also, sometimes, to enhance in vivo distribution. This chapter presents some examples of the research done in this way with a special focus on redox active compounds.
Natural products molten together: Toward multifunctional hybrid molecules with specific activities and applications / Kirsch, G.; Valente, S.. - (2014), pp. 379-397. [10.1007/978-94-017-8953-0_15].
Natural products molten together: Toward multifunctional hybrid molecules with specific activities and applications
Valente, S.
2014
Abstract
It happens in Nature that compounds with interesting biological activity are formed of individual blocks of different structures, which are generally active by themselves. For example, different acids such as quinic acid or shikimic acid, are found to be conjugated to caffeic acid. In these cases the combination is the result of a biosynthetic process. At the same time, chemists were interested in melting together natural products known for specific activity in a way to obtain a multiple shot for the biological effect or also, sometimes, to enhance in vivo distribution. This chapter presents some examples of the research done in this way with a special focus on redox active compounds.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
