Several metabolic processes are altered by kidney transplantation (KT), mainly due to a mechanism of overlapping between preexisting favoring conditions and side effects of immunosuppressive agents. Among the metabolic alterations commonly observed after KT, diabetes mellitus, dyslipidemias, and uric acid metabolism represent the most important ones, mainly due to the clinical impact they may present not only in relation to graft function but also in terms of patient survival. The most recent (as of 2017) national guidelines, randomized controlled trials, and metaanalyses on these arguments are reported in this chapter, with the intent to better clarify the therapeutic strategies to adopt in case of metabolic disorder after KT.
Metabolic Disorders Following Kidney Transplantation / Lai, Q.; Pisani, F.. - (2017), pp. 513-523. [10.1016/B978-0-12-801734-0.00036-9].
Metabolic Disorders Following Kidney Transplantation
Lai Q.;
2017
Abstract
Several metabolic processes are altered by kidney transplantation (KT), mainly due to a mechanism of overlapping between preexisting favoring conditions and side effects of immunosuppressive agents. Among the metabolic alterations commonly observed after KT, diabetes mellitus, dyslipidemias, and uric acid metabolism represent the most important ones, mainly due to the clinical impact they may present not only in relation to graft function but also in terms of patient survival. The most recent (as of 2017) national guidelines, randomized controlled trials, and metaanalyses on these arguments are reported in this chapter, with the intent to better clarify the therapeutic strategies to adopt in case of metabolic disorder after KT.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
