Optical coherence tomography (OCT) is a non-invasive imaging technology that offers a view into the superficial layers of the skin in vivo in real-time. An infrared broadband light source allows the visualization of micro structural morphology of tissues and changes up to a depth of 1–2 mm with a resolution between 3 and 15 μm, depending on the system used. The combination of the classical cross-sectional OCT images (vertical) and en-face view (horizontal) is now established routine and adds additional value to the diagnostic capability of the technique. Moreover, technological developments have led to an increased resolution, a larger field of view as well as an increased scanning speed in current systems. OCT enables evaluation of non-melanoma skin cancers, melanocytic lesions and inflammatory diseases, assessment of wound, investigation of hair and nail disorders, quantification of skin changes and therapy monitoring. Dynamic OCT (D-OCT) allows the in vivo evaluation of blood vessels and their distribution within specific lesions, providing additional functional information and consequently greater density of data. D-OCT is applicable in skin cancers including melanoma, as well as in a variety of inflammatory skin diseases, chronic wounds and other areas of dermatological research. This chapter will give an overview of this technology and its indications.
Optical Coherence Tomography / Mandel, Victor Desmond; Pellacani, Giovanni. - (2020), pp. 219-240. [10.1007/978-3-030-45351-0_22].
Optical Coherence Tomography
PELLACANI, Giovanni
2020
Abstract
Optical coherence tomography (OCT) is a non-invasive imaging technology that offers a view into the superficial layers of the skin in vivo in real-time. An infrared broadband light source allows the visualization of micro structural morphology of tissues and changes up to a depth of 1–2 mm with a resolution between 3 and 15 μm, depending on the system used. The combination of the classical cross-sectional OCT images (vertical) and en-face view (horizontal) is now established routine and adds additional value to the diagnostic capability of the technique. Moreover, technological developments have led to an increased resolution, a larger field of view as well as an increased scanning speed in current systems. OCT enables evaluation of non-melanoma skin cancers, melanocytic lesions and inflammatory diseases, assessment of wound, investigation of hair and nail disorders, quantification of skin changes and therapy monitoring. Dynamic OCT (D-OCT) allows the in vivo evaluation of blood vessels and their distribution within specific lesions, providing additional functional information and consequently greater density of data. D-OCT is applicable in skin cancers including melanoma, as well as in a variety of inflammatory skin diseases, chronic wounds and other areas of dermatological research. This chapter will give an overview of this technology and its indications.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.