Genes

The adaptation of microorganisms to low pH has many important practical applications in a number of diverse sectors such as food and drink microbiology, industrial biotechnology and bio-processing, and clinical and veterinary treatment of infections, in a time of increasing antimicrobial resistance. The microorganisms under consideration include bacteria, yeasts, and other fungi. With this Special Issue, we aim to collect high-quality research articles describing the genomic, transcriptomic, sensing, and metabolic landscape of the microbial responses to low pH with a view to understanding their functional significance and bridging to potential applications gathered from the covered knowledge. We wish to cover all aspects of the molecular events from sensing to responding to low pH stress, and also to cover descriptions of genes in different organisms that may have specific functions at low pH. Adaptation is therefore meant both in terms of the short-term response, and also in the description of how evolution has enabled microorganisms to be resilient to acid stress. This is in line with the objectives of the COST Action “EuroMicropH” (https://euromicroph.eu), which is committed to aiding the understanding of the details of how model and non-model micro-organisms detect and respond to low pH. Prof. Daniela De Biase Dr. Peter A. Lund Prof. Nuno Pereira Mira Guest Editors