Banks of genetically characterized cancer stem cells (CSCs) isolated from individual patients and grown as spheroids offer an invaluable approach to identify genetic determinants of drug resistance versus sensitivity, and to study new stem cell-directed therapies. Here, we describe our standardized procedure for in vitro drug screening on colorectal CSCs, taking irinotecan as an example.
How to assess drug resistance in cancer stem cells / De Angelis, Maria Laura; De Maria, Ruggero; Baiocchi, Marta. - (2018), pp. 107-115. [10.1007/978-1-4939-7401-6_10].
How to assess drug resistance in cancer stem cells
Baiocchi, Marta
2018
Abstract
Banks of genetically characterized cancer stem cells (CSCs) isolated from individual patients and grown as spheroids offer an invaluable approach to identify genetic determinants of drug resistance versus sensitivity, and to study new stem cell-directed therapies. Here, we describe our standardized procedure for in vitro drug screening on colorectal CSCs, taking irinotecan as an example.File allegati a questo prodotto
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