In the last few decades, there have been an increasing number of studies focusing on better characterizing the cerebellar functions beyond motor control, including emotional and social domains. Anatomical and functional evidence strongly contributes to delineating the cerebellar functional subdivisions and their integration with cerebral functional networks strictly related to emotional regulation and social functioning, thus suggesting a model of cerebellar organization that resembles that of the cerebral cortex. Overcoming the traditional segregation of cerebro-cerebellar networks in sensorimotor/cognitive functional modules, during emotional/social processes, the cerebellar activity reflects a domain-specific mentalizing functionality that is strongly connected with corresponding mentalizing networks in the cerebrum. Additionally, the cerebro-cerebellar organization has been shown to have a specific functional and maturational trajectory that is only in part dependent on a structural maturational process and that is protracted from an early stage of life through adolescence and adulthood, when the mature control networks involve both segregation and integration of the brain regions that comprise them. Altogether, these findings underscore the importance of regional functional differences within the cerebellum in relation to emotional and social processing and raise questions about the clinical implication of cerebellar injury on emotional/social behaviours, both in the developing and the adult brain.

Topography of the cerebellum in relationship to social brain regions and emotions / Leggio, Maria; Olivito, Giusy. - STAMPA. - (2018), pp. 71-84. - HANDBOOK OF CLINICAL NEUROLOGY. [10.1016/B978-0-444-63956-1.00005-9].

Topography of the cerebellum in relationship to social brain regions and emotions

Maria Leggio
Primo
;
Giusy Olivito
Ultimo
2018

Abstract

In the last few decades, there have been an increasing number of studies focusing on better characterizing the cerebellar functions beyond motor control, including emotional and social domains. Anatomical and functional evidence strongly contributes to delineating the cerebellar functional subdivisions and their integration with cerebral functional networks strictly related to emotional regulation and social functioning, thus suggesting a model of cerebellar organization that resembles that of the cerebral cortex. Overcoming the traditional segregation of cerebro-cerebellar networks in sensorimotor/cognitive functional modules, during emotional/social processes, the cerebellar activity reflects a domain-specific mentalizing functionality that is strongly connected with corresponding mentalizing networks in the cerebrum. Additionally, the cerebro-cerebellar organization has been shown to have a specific functional and maturational trajectory that is only in part dependent on a structural maturational process and that is protracted from an early stage of life through adolescence and adulthood, when the mature control networks involve both segregation and integration of the brain regions that comprise them. Altogether, these findings underscore the importance of regional functional differences within the cerebellum in relation to emotional and social processing and raise questions about the clinical implication of cerebellar injury on emotional/social behaviours, both in the developing and the adult brain.
2018
The Cerebellum. From Embryology to Diagnostic Investigations
9780444639561
9780444639578
emotion; social cognition; cerebellum; functional connectivity; cerebro-cerebellar networks; neurodevelopment; default mode network; salience network; limbic cerebellum
02 Pubblicazione su volume::02a Capitolo o Articolo
Topography of the cerebellum in relationship to social brain regions and emotions / Leggio, Maria; Olivito, Giusy. - STAMPA. - (2018), pp. 71-84. - HANDBOOK OF CLINICAL NEUROLOGY. [10.1016/B978-0-444-63956-1.00005-9].
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/1132786
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