The presence of antiviral compounds in the Guttiferae family as medicinal plants and the long traditional use of species of the genus Hypericum for the treatment of many viral infections have developed a strong interest. Among the natural products of plant origin, the ones from Hypericum genus were cited as promising anti-HIV agents. This chapter will report an updated review of carbocyclic nucleoside analogues as anti-HIV agents from iridoids. Moreover, the partial synthesis of antiviral agents from iridoid glucosides to carbocyclic nucleosides as new anti-HIV agents is reviewed.

Anti-HIV agents from nature: natural compounds from hypericum hircinum and carbocyclic nucleosides from iridoids / Ornano, Luigi; Feroci, Marta; Guarcini, Laura; Venditti, Alessandro; Bianco, Armandodoriano. - STAMPA. - 56(2018), pp. 173-228. [10.1016/B978-0-444-64058-1.00006-6].

Anti-HIV agents from nature: natural compounds from hypericum hircinum and carbocyclic nucleosides from iridoids

Ornano, Luigi
Membro del Collaboration Group
;
Feroci, Marta
Membro del Collaboration Group
;
Guarcini, Laura
Membro del Collaboration Group
;
Venditti, Alessandro
Membro del Collaboration Group
;
Bianco, Armandodoriano
Membro del Collaboration Group
2018

Abstract

The presence of antiviral compounds in the Guttiferae family as medicinal plants and the long traditional use of species of the genus Hypericum for the treatment of many viral infections have developed a strong interest. Among the natural products of plant origin, the ones from Hypericum genus were cited as promising anti-HIV agents. This chapter will report an updated review of carbocyclic nucleoside analogues as anti-HIV agents from iridoids. Moreover, the partial synthesis of antiviral agents from iridoid glucosides to carbocyclic nucleosides as new anti-HIV agents is reviewed.
978-0-444-64058-1
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/1066155
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