This chapter discusses recent trends in the development of label-free biosensors based on bioelectronic interfaces consisting of graphene decorated with DNA molecules. In particular, the chapter outlines the available strategies for the conjugation of DNA onto graphene surface, exploiting both covalent and noncovalent types of interaction, toward the fabrication of biocompatible and conductive biosensing platforms with high specificity. We describe how the unique properties of the graphene/DNA biointerface can be used for the selective detection of a wide range of molecular targets in the biomedical and environmental fields, from nucleotides to metal ions. The chapter also highlights our recent results in the use of the graphene/DNA interface as the key element in novel UV-radiation-sensing devices. The bioelectronic interface formed by DNA and graphene has shown great potential for monitoring, in a real-time fashion, the biological damage induced by exposure to UV radiation in extreme environments.
Label-free biosensing platforms based on graphene/DNA interfaces / Santonicola, Mariagabriella. - STAMPA. - (2017), pp. 177-191. [10.1016/B978-0-12-813349-1.00008-1].
|Titolo:||Label-free biosensing platforms based on graphene/DNA interfaces|
SANTONICOLA, MARIAGABRIELLA (Corresponding author)
|Data di pubblicazione:||2017|
|Citazione:||Label-free biosensing platforms based on graphene/DNA interfaces / Santonicola, Mariagabriella. - STAMPA. - (2017), pp. 177-191. [10.1016/B978-0-12-813349-1.00008-1].|
|Appartiene alla tipologia:||02a Capitolo o Articolo|
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