This work reports on the design, simulation and fabrication of an autonomous microfluidic network. It is a part of a highly integrated, new analytical platform for the multiparametric detection of bio-organic molecules in extra-terrestrial environment. The proposed microfluidic system, made in SU-8 3050, allows to obtain an au-tonomous microfluidic network able to have simultaneous capillary filling and fresh solution into each site of detection avoiding cross-contamination among different sites. Computational Fluid Dynam-ics (CFD) simulations have been carried in order to verify the prop-er operation of the designed microfluidic network and to optimize it. Technological processes have been refined and adapted in order to ensure good adhesion, using low-temperature and low-pressure bonding avoiding the risk of breaking the glass slides. Experiments have been conducted to verify the autonomous capillary filling of the entire network and its rinsing with buffer solution. The experi-mental results are in good agreement with the simulations.

Best Poster Awards at AISEM 2017 / Nardecchia, Marco. - (2017).

Best Poster Awards at AISEM 2017

NARDECCHIA, MARCO
2017

Abstract

This work reports on the design, simulation and fabrication of an autonomous microfluidic network. It is a part of a highly integrated, new analytical platform for the multiparametric detection of bio-organic molecules in extra-terrestrial environment. The proposed microfluidic system, made in SU-8 3050, allows to obtain an au-tonomous microfluidic network able to have simultaneous capillary filling and fresh solution into each site of detection avoiding cross-contamination among different sites. Computational Fluid Dynam-ics (CFD) simulations have been carried in order to verify the prop-er operation of the designed microfluidic network and to optimize it. Technological processes have been refined and adapted in order to ensure good adhesion, using low-temperature and low-pressure bonding avoiding the risk of breaking the glass slides. Experiments have been conducted to verify the autonomous capillary filling of the entire network and its rinsing with buffer solution. The experi-mental results are in good agreement with the simulations.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/1000294
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