LAMBONA, CHIARA
LAMBONA, CHIARA
DIPARTIMENTO DI SCIENZE BIOCHIMICHE "ALESSANDRO ROSSI FANELLI"
Combined computational and classical medicinal chemistry procedure to disclose novel pyrrole-based compounds as potential antituberculosis agents
2026 Ragno, Rino; Zwergel, Clemens; Valente, Sergio; Astolfi, Roberta; Lambona, Chiara; Proia, Eleonora; Giuliani, Lidia; Franzblau, Scott G.; Fioravanti, Rossella; Mai, Antonello
Design of Benzyl-triazolopyrimidine-Based NADPH Oxidase Inhibitors Leads to the Discovery of a Potent Dual Covalent NOX2/MAOB Inhibitor
2025 Noce, Beatrice; Marchese, Sara; Massari, Marta; Lambona, Chiara; Reis, Joana; Fiorentino, Francesco; Raucci, Alessia; Fioravanti, Rossella; Castelôa, Mariana; Mormino, Alessandro; Garofalo, Stefano; Limatola, Cristina; Basile, Lorenzo; Gottinger, Andrea; Binda, Claudia; Mattevi, Andrea; Mai, Antonello; Valente, Sergio
First-in-Class Selenium-Containing Potent Serotonin Receptor 5-HT6 Agents with a Beneficial Neuroprotective Profile against Alzheimer's Disease
2024 Pyka, Patryk; Haberek, Wawrzyniec; Więcek, Małgorzata; Szymanska, Ewa; Ali, Wesam; Cios, Agnieszka; Jastrzębska-Więsek, Magdalena; Satała, Grzegorz; Podlewska, Sabina; Di Giacomo, Silvia; Di Sotto, Antonella; Garbo, Sabrina; Karcz, Tadeusz; Lambona, Chiara; Marocco, Francesco; Latacz, Gniewomir; Sudoł-Tałaj, Sylwia; Mordyl, Barbara; Głuch-Lutwin, Monika; Siwek, Agata; Czarnota-Łydka, Kinga; Gogola, Dawid; Olejarz-Maciej, Agnieszka; Wilczyńska-Zawal, Natalia; Honkisz-Orzechowska, Ewelina; Starek, Małgorzata; Dąbrowska, Monika; Kucwaj-Brysz, Katarzyna; Fioravanti, Rossella; Nasim, Muhammad Jawad; Hittinger, Marius; Partyka, Anna; Wesołowska, Anna; Battistelli, Cecilia; Zwergel, Clemens; Handzlik, Jadwiga
Histone deacetylase 10: A polyamine deacetylase from the crystal structure to the first inhibitors
2023 Lambona, Chiara; Zwergel, Clemens; Fioravanti, Rossella; Valente, Sergio; Mai, Antonello
Inhibition of bromodomain and extra-terminal motif (BET) proteins in pediatric sarcoma. A systematic review of in vitro and in vivo studies
2025 Ferraro, Erika; Macrì, Elisa; Zwergel, Clemens; Lambona, Chiara; Barillari, Giovanni; Marchese, Cinzia; Locatelli, Franco; Rota, Rossella; Cassandri, Matteo; Pomella, Silvia
Novel 1,4-Dihydropyridines as Specific Binders and Activators of SIRT3 Impair Cell Viability and Clonogenicity and Downregulate Hypoxia-Induced Targets in Cancer Cells
2023 Zwergel, Clemens; Aventaggiato, Michele; Garbo, Sabrina; DI BELLO, Elisabetta; Fassari, Bruno; Noce, Beatrice; Castiello, Carola; Lambona, Chiara; Barreca, Federica; Rotili, Dante; Fioravanti, Rossella; Schmalz, Thomas; Weyand, Michael; Niedermeier, Amelie; Tripodi, Marco; Colotti, Gianni; Steegborn, Clemens; Battistelli, Cecilia; Tafani, Marco; Valente, Sergio; Mai, Antonello
Quinoline-based DNA methyltransferase inhibitors featuring basic side chains: design, synthesis, and insight in biochemical and anticancer cell properties
2025 Zwergel, Clemens; Lambona, Chiara; Fioravanti, Rossella; Raucci, Alessia; Fiorentino, Francesco; Nchugoua Tchieh, Guilaine; Jallet, Corinne; Lacroix, Laurent; Pierrettori, Michela; Pellegrini, Francesca Romana; Xiong, Yan; Jin, Jian; Arimondo, Paola; Trisciuoglio, Daniela; Mai, Antonello; Valente, Sergio
SIRT3 Activation a Promise in Drug Development? New Insights into SIRT3 Biology and Its Implications on the Drug Discovery Process
2024 Lambona, Chiara; Zwergel, Clemens; Valente, Sergio; Mai, Antonello
Tranylcypromine-Based LSD1 Inhibitors as Useful Agents to Reduce Viability of Schistosoma mansoni
2025 Fabbrizi, Emanuele; Hailu, Gebremedhin Solomon; Ganesan, A.; Fioravanti, Rossella; Zwergel, Clemens; Lambona, Chiara; Valente, Sergio; Fianco, Giulia; Iuzzolino, Angela; Trisciuoglio, Daniela; Caroli, Jonatan; Mattevi, Andrea; Häberli, Cécile; Keiser, Jennifer; Rotili, Dante; Mai, Antonello
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| Combined computational and classical medicinal chemistry procedure to disclose novel pyrrole-based compounds as potential antituberculosis agents | 2026 | Ragno, Rino; Zwergel, Clemens; Valente, Sergio; Astolfi, Roberta; Lambona, Chiara; Proia, Eleonora; Giuliani, Lidia; Franzblau, Scott G.; Fioravanti, Rossella; Mai, Antonello | |
| Design of Benzyl-triazolopyrimidine-Based NADPH Oxidase Inhibitors Leads to the Discovery of a Potent Dual Covalent NOX2/MAOB Inhibitor | 2025 | Noce, Beatrice; Marchese, Sara; Massari, Marta; Lambona, Chiara; Reis, Joana; Fiorentino, Francesco; Raucci, Alessia; Fioravanti, Rossella; Castelôa, Mariana; Mormino, Alessandro; Garofalo, Stefano; Limatola, Cristina; Basile, Lorenzo; Gottinger, Andrea; Binda, Claudia; Mattevi, Andrea; Mai, Antonello; Valente, Sergio | |
| First-in-Class Selenium-Containing Potent Serotonin Receptor 5-HT6 Agents with a Beneficial Neuroprotective Profile against Alzheimer's Disease | 2024 | Pyka, Patryk; Haberek, Wawrzyniec; Więcek, Małgorzata; Szymanska, Ewa; Ali, Wesam; Cios, Agnieszka; Jastrzębska-Więsek, Magdalena; Satała, Grzegorz; Podlewska, Sabina; Di Giacomo, Silvia; Di Sotto, Antonella; Garbo, Sabrina; Karcz, Tadeusz; Lambona, Chiara; Marocco, Francesco; Latacz, Gniewomir; Sudoł-Tałaj, Sylwia; Mordyl, Barbara; Głuch-Lutwin, Monika; Siwek, Agata; Czarnota-Łydka, Kinga; Gogola, Dawid; Olejarz-Maciej, Agnieszka; Wilczyńska-Zawal, Natalia; Honkisz-Orzechowska, Ewelina; Starek, Małgorzata; Dąbrowska, Monika; Kucwaj-Brysz, Katarzyna; Fioravanti, Rossella; Nasim, Muhammad Jawad; Hittinger, Marius; Partyka, Anna; Wesołowska, Anna; Battistelli, Cecilia; Zwergel, Clemens; Handzlik, Jadwiga | |
| Histone deacetylase 10: A polyamine deacetylase from the crystal structure to the first inhibitors | 2023 | Lambona, Chiara; Zwergel, Clemens; Fioravanti, Rossella; Valente, Sergio; Mai, Antonello | |
| Inhibition of bromodomain and extra-terminal motif (BET) proteins in pediatric sarcoma. A systematic review of in vitro and in vivo studies | 2025 | Ferraro, Erika; Macrì, Elisa; Zwergel, Clemens; Lambona, Chiara; Barillari, Giovanni; Marchese, Cinzia; Locatelli, Franco; Rota, Rossella; Cassandri, Matteo; Pomella, Silvia | |
| Novel 1,4-Dihydropyridines as Specific Binders and Activators of SIRT3 Impair Cell Viability and Clonogenicity and Downregulate Hypoxia-Induced Targets in Cancer Cells | 2023 | Zwergel, Clemens; Aventaggiato, Michele; Garbo, Sabrina; DI BELLO, Elisabetta; Fassari, Bruno; Noce, Beatrice; Castiello, Carola; Lambona, Chiara; Barreca, Federica; Rotili, Dante; Fioravanti, Rossella; Schmalz, Thomas; Weyand, Michael; Niedermeier, Amelie; Tripodi, Marco; Colotti, Gianni; Steegborn, Clemens; Battistelli, Cecilia; Tafani, Marco; Valente, Sergio; Mai, Antonello | |
| Quinoline-based DNA methyltransferase inhibitors featuring basic side chains: design, synthesis, and insight in biochemical and anticancer cell properties | 2025 | Zwergel, Clemens; Lambona, Chiara; Fioravanti, Rossella; Raucci, Alessia; Fiorentino, Francesco; Nchugoua Tchieh, Guilaine; Jallet, Corinne; Lacroix, Laurent; Pierrettori, Michela; Pellegrini, Francesca Romana; Xiong, Yan; Jin, Jian; Arimondo, Paola; Trisciuoglio, Daniela; Mai, Antonello; Valente, Sergio | |
| SIRT3 Activation a Promise in Drug Development? New Insights into SIRT3 Biology and Its Implications on the Drug Discovery Process | 2024 | Lambona, Chiara; Zwergel, Clemens; Valente, Sergio; Mai, Antonello | |
| Tranylcypromine-Based LSD1 Inhibitors as Useful Agents to Reduce Viability of Schistosoma mansoni | 2025 | Fabbrizi, Emanuele; Hailu, Gebremedhin Solomon; Ganesan, A.; Fioravanti, Rossella; Zwergel, Clemens; Lambona, Chiara; Valente, Sergio; Fianco, Giulia; Iuzzolino, Angela; Trisciuoglio, Daniela; Caroli, Jonatan; Mattevi, Andrea; Häberli, Cécile; Keiser, Jennifer; Rotili, Dante; Mai, Antonello |