BENEDETTI, ROSSELLA
BENEDETTI, ROSSELLA
DIPARTIMENTO DI MEDICINA SPERIMENTALE
Acetylation increases expression, interaction with TRAPPC4 and surface localization of PD-L1
2023 Romeo, Maria Anele; Gilardini Montani, Maria Saveria; Santarelli, Roberta; Benedetti, Rossella; Arena, Andrea; Cirone, Mara
Anticancer effect of AZD2461 PARP inhibitor against colon cancer cells carrying wt or dysfunctional p53
2021 Romeo, M. A.; Gilardini Montani, M. S.; Benedetti, R.; Arena, A.; Maretto, M.; Bassetti, E.; Caiazzo, R.; D'Orazi, G.; Cirone, M.
ATF6 prevents DNA damage and cell death in colon cancer cells undergoing ER stress
2022 Benedetti, Rossella; Romeo, Maria Anele; Arena, Andrea; Gilardini Montani, Maria Saveria; Di Renzo, Livia; D'Orazi, Gabriella; Cirone, Mara
c-Myc Sustains Pancreatic Cancer Cell Survival and mutp53 Stability through the Mevalonate Pathway
2022 Romeo, Maria Anele; GILARDINI MONTANI, MARIA SAVERIA; Arena, Andrea; Benedetti, Rossella; D’Orazi, Gabriella; Cirone, Mara
Concomitant Inhibition of IRE1α/XBP1 Axis of UPR and PARP. A Promising Therapeutic Approach against c-Myc and Gammaherpesvirus-Driven B-Cell Lymphomas
2022 Benedetti, R.; Arena, A.; Romeo, M. A.; Gilardini Montani, M. S.; Gonnella, R.; Santarelli, R.; Trivedi, P.; Cirone, M.
Different outcome of targeting ERN1/IRE1 alpha and EIF2AK3/PERK in NSG mice engrafted with primary effusion lymphoma
2023 Arena, Andrea; Romeo, Maria Anele; Focaccetti, Chiara; Anastasiadou, Eleni; Trivedi, Pankaj; Cifaldi, Loredana; Gilardini Montani, Maria Saveria; Benedetti, Rossella; Santarelli, Roberta; Gonnella, Roberta; Benvenuto, Monica; Marchese, Cinzia; Masuelli, Laura; Bei, Roberto; Cirone, Mara
DNA damage triggers an interplay between wtp53 and c-Myc affecting lymphoma cell proliferation and Kaposi sarcoma herpesvirus replication
2022 Arena, A.; Gilardini Montani, M. S.; Romeo, M. A.; Benedetti, R.; Gaeta, A.; Cirone, M.
HSP110 Inhibition in Primary Effusion Lymphoma Cells. One Molecule, Many Pro-Survival Targets
2023 Gonnella, Roberta; Zarrella, Roberta; DI CROSTA, Michele; Benedetti, Rossella; Arena, Andrea; Santarelli, Roberta; GILARDINI MONTANI, MARIA SAVERIA; D’Orazi, Gabriella; Cirone, Mara
JQ-1/bortezomib combination strongly impairs MM and PEL survival by inhibiting c-Myc and mTOR despite the activation of prosurvival mechanisms
2023 Arena, Andrea; Romeo, Maria Anele; Benedetti, Rossella; Gilardini Montani, Maria Saveria; Cirone, Mara
New insights into curcumin-and resveratrol-mediated anti-cancer effects
2021 Arena, A.; Romeo, M. A.; Benedetti, R.; Masuelli, L.; Bei, R.; Gilardini Montani, M. S.; Cirone, M.
NFE2L2 and STAT3 converge on common targets to promote survival of primary lymphoma cells
2023 Arena, Andrea; DI CROSTA, Michele; Gonnella, Roberta; Zarrella, Roberta; Romeo, Maria Anele; Benedetti, Rossella; GILARDINI MONTANI, MARIA SAVERIA; Santarelli, Roberta; D’Orazi, Gabriella; Cirone, Mara
NRF2 and STAT3: friends or foes in carcinogenesis?
2023 Arena, Andrea; Romeo, Maria Anele; Benedetti, Rossella; Gilardini Montani, Maria Saveria; Santarelli, Roberta; Gonnella, Roberta; D'Orazi, Gabriella; Cirone, Mara
p53-R273H Sustains ROS, Pro-Inflammatory Cytokine Release and mTOR Activation While Reducing Autophagy, Mitophagy and UCP2 Expression, Effects Prevented by wtp53
2021 Romeo, M. A.; Gilardini Montani, M. S.; Benedetti, R.; Arena, A.; D'Orazi, G.; Cirone, M.
p62/SQSTM1 promotes mitophagy and activates the NRF2-mediated antioxidant and anti-inflammatory response restraining EBV-driven B lymphocyte proliferation
2022 GILARDINI MONTANI, MARIA SAVERIA; Tarquini, Greta; Santarelli, Roberta; Gonnella, Roberta; Romeo, Maria Anele; Benedetti, Rossella; Arena, Andrea; Faggioni, Alberto; Cirone, Mara
PBA preferentially impairs cell survival of glioblastomas carrying mutp53 by reducing its expression level, stabilizing wtp53, downregulating the mevalonate kinase and dysregulating UPR
2020 Romeo, M. A.; Gilardini Montani, M. S.; Benedetti, R.; Garufi, A.; D'Orazi, G.; Cirone, M.
PGE2 released by pancreatic cancer cells undergoing ER stress transfers the stress to DCs impairing their immune function
2021 Gilardini Montani, M. S.; Benedetti, R.; Piconese, S.; Pulcinelli, F. M.; Timperio, A. M.; Romeo, M. A.; Masuelli, L.; Mattei, M.; Bei, R.; D'Orazi, G.; Cirone, M.
Role of upr sensor activation in cell death–survival decision of colon cancer cells stressed by dpe treatment
2021 Benedetti, R.; Gilardini Montani, M. S.; Romeo, M. A.; Arena, A.; Santarelli, R.; D'Orazi, G.; Cirone, M.
STAT3 and mutp53 Engage a Positive Feedback Loop Involving HSP90 and the Mevalonate Pathway
2020 Romeo, M. A.; Gilardini Montani, M. S.; Benedetti, R.; Santarelli, R.; D'Orazi, G.; Cirone, M.
Targeting c-Myc Unbalances UPR towards Cell Death and Impairs DDR in Lymphoma and Multiple Myeloma Cells
2022 Arena, A.; Romeo, M. A.; Benedetti, R.; Gilardini Montani, M. S.; Cirone, M.
The cross-talk between STAT1/STAT3 and ROS up-regulates PD-L1 and promotes the release of pro-inflammatory/immune suppressive cytokines in primary monocytes infected by HHV-6B
2021 Romeo, M. A.; Gilardini Montani, M. S.; Benedetti, R.; Giambelli, L.; D'Aprile, R.; Gaeta, A.; Faggioni, A.; Cirone, M.
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| Acetylation increases expression, interaction with TRAPPC4 and surface localization of PD-L1 | 2023 | Romeo, Maria Anele; Gilardini Montani, Maria Saveria; Santarelli, Roberta; Benedetti, Rossella; Arena, Andrea; Cirone, Mara | |
| Anticancer effect of AZD2461 PARP inhibitor against colon cancer cells carrying wt or dysfunctional p53 | 2021 | Romeo, M. A.; Gilardini Montani, M. S.; Benedetti, R.; Arena, A.; Maretto, M.; Bassetti, E.; Caiazzo, R.; D'Orazi, G.; Cirone, M. | |
| ATF6 prevents DNA damage and cell death in colon cancer cells undergoing ER stress | 2022 | Benedetti, Rossella; Romeo, Maria Anele; Arena, Andrea; Gilardini Montani, Maria Saveria; Di Renzo, Livia; D'Orazi, Gabriella; Cirone, Mara | |
| c-Myc Sustains Pancreatic Cancer Cell Survival and mutp53 Stability through the Mevalonate Pathway | 2022 | Romeo, Maria Anele; GILARDINI MONTANI, MARIA SAVERIA; Arena, Andrea; Benedetti, Rossella; D’Orazi, Gabriella; Cirone, Mara | |
| Concomitant Inhibition of IRE1α/XBP1 Axis of UPR and PARP. A Promising Therapeutic Approach against c-Myc and Gammaherpesvirus-Driven B-Cell Lymphomas | 2022 | Benedetti, R.; Arena, A.; Romeo, M. A.; Gilardini Montani, M. S.; Gonnella, R.; Santarelli, R.; Trivedi, P.; Cirone, M. | |
| Different outcome of targeting ERN1/IRE1 alpha and EIF2AK3/PERK in NSG mice engrafted with primary effusion lymphoma | 2023 | Arena, Andrea; Romeo, Maria Anele; Focaccetti, Chiara; Anastasiadou, Eleni; Trivedi, Pankaj; Cifaldi, Loredana; Gilardini Montani, Maria Saveria; Benedetti, Rossella; Santarelli, Roberta; Gonnella, Roberta; Benvenuto, Monica; Marchese, Cinzia; Masuelli, Laura; Bei, Roberto; Cirone, Mara | |
| DNA damage triggers an interplay between wtp53 and c-Myc affecting lymphoma cell proliferation and Kaposi sarcoma herpesvirus replication | 2022 | Arena, A.; Gilardini Montani, M. S.; Romeo, M. A.; Benedetti, R.; Gaeta, A.; Cirone, M. | |
| HSP110 Inhibition in Primary Effusion Lymphoma Cells. One Molecule, Many Pro-Survival Targets | 2023 | Gonnella, Roberta; Zarrella, Roberta; DI CROSTA, Michele; Benedetti, Rossella; Arena, Andrea; Santarelli, Roberta; GILARDINI MONTANI, MARIA SAVERIA; D’Orazi, Gabriella; Cirone, Mara | |
| JQ-1/bortezomib combination strongly impairs MM and PEL survival by inhibiting c-Myc and mTOR despite the activation of prosurvival mechanisms | 2023 | Arena, Andrea; Romeo, Maria Anele; Benedetti, Rossella; Gilardini Montani, Maria Saveria; Cirone, Mara | |
| New insights into curcumin-and resveratrol-mediated anti-cancer effects | 2021 | Arena, A.; Romeo, M. A.; Benedetti, R.; Masuelli, L.; Bei, R.; Gilardini Montani, M. S.; Cirone, M. | |
| NFE2L2 and STAT3 converge on common targets to promote survival of primary lymphoma cells | 2023 | Arena, Andrea; DI CROSTA, Michele; Gonnella, Roberta; Zarrella, Roberta; Romeo, Maria Anele; Benedetti, Rossella; GILARDINI MONTANI, MARIA SAVERIA; Santarelli, Roberta; D’Orazi, Gabriella; Cirone, Mara | |
| NRF2 and STAT3: friends or foes in carcinogenesis? | 2023 | Arena, Andrea; Romeo, Maria Anele; Benedetti, Rossella; Gilardini Montani, Maria Saveria; Santarelli, Roberta; Gonnella, Roberta; D'Orazi, Gabriella; Cirone, Mara | |
| p53-R273H Sustains ROS, Pro-Inflammatory Cytokine Release and mTOR Activation While Reducing Autophagy, Mitophagy and UCP2 Expression, Effects Prevented by wtp53 | 2021 | Romeo, M. A.; Gilardini Montani, M. S.; Benedetti, R.; Arena, A.; D'Orazi, G.; Cirone, M. | |
| p62/SQSTM1 promotes mitophagy and activates the NRF2-mediated antioxidant and anti-inflammatory response restraining EBV-driven B lymphocyte proliferation | 2022 | GILARDINI MONTANI, MARIA SAVERIA; Tarquini, Greta; Santarelli, Roberta; Gonnella, Roberta; Romeo, Maria Anele; Benedetti, Rossella; Arena, Andrea; Faggioni, Alberto; Cirone, Mara | |
| PBA preferentially impairs cell survival of glioblastomas carrying mutp53 by reducing its expression level, stabilizing wtp53, downregulating the mevalonate kinase and dysregulating UPR | 2020 | Romeo, M. A.; Gilardini Montani, M. S.; Benedetti, R.; Garufi, A.; D'Orazi, G.; Cirone, M. | |
| PGE2 released by pancreatic cancer cells undergoing ER stress transfers the stress to DCs impairing their immune function | 2021 | Gilardini Montani, M. S.; Benedetti, R.; Piconese, S.; Pulcinelli, F. M.; Timperio, A. M.; Romeo, M. A.; Masuelli, L.; Mattei, M.; Bei, R.; D'Orazi, G.; Cirone, M. | |
| Role of upr sensor activation in cell death–survival decision of colon cancer cells stressed by dpe treatment | 2021 | Benedetti, R.; Gilardini Montani, M. S.; Romeo, M. A.; Arena, A.; Santarelli, R.; D'Orazi, G.; Cirone, M. | |
| STAT3 and mutp53 Engage a Positive Feedback Loop Involving HSP90 and the Mevalonate Pathway | 2020 | Romeo, M. A.; Gilardini Montani, M. S.; Benedetti, R.; Santarelli, R.; D'Orazi, G.; Cirone, M. | |
| Targeting c-Myc Unbalances UPR towards Cell Death and Impairs DDR in Lymphoma and Multiple Myeloma Cells | 2022 | Arena, A.; Romeo, M. A.; Benedetti, R.; Gilardini Montani, M. S.; Cirone, M. | |
| The cross-talk between STAT1/STAT3 and ROS up-regulates PD-L1 and promotes the release of pro-inflammatory/immune suppressive cytokines in primary monocytes infected by HHV-6B | 2021 | Romeo, M. A.; Gilardini Montani, M. S.; Benedetti, R.; Giambelli, L.; D'Aprile, R.; Gaeta, A.; Faggioni, A.; Cirone, M. |