Nome |
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Modulating the dose-rate differently affects the responsiveness of human epithelial prostate- and mesenchymal rhabdomyosarcoma-cancer cell line to radiation, file e3835325-627c-15e8-e053-a505fe0a3de9
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310
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Distinctive binding properties of the negative allosteric modulator, [3H]SB269,652, at recombinant dopamine D3 receptors, file e3835320-88ba-15e8-e053-a505fe0a3de9
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229
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Cellular and molecular mediators of bone metastatic lesions, file e383531a-c5ae-15e8-e053-a505fe0a3de9
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159
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The novel CXCR4 antagonist, PRX177561, reduces tumor cell proliferation and accelerates cancer stem cell differentiation in glioblastoma preclinical models, file e3835320-88b2-15e8-e053-a505fe0a3de9
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152
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HDAC inhibition is associated to valproic acid induction of early megakaryocytic markers, file e3835320-83cf-15e8-e053-a505fe0a3de9
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150
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The first-in-class alkylating deacetylase inhibitor molecule tinostamustine shows antitumor effects and is synergistic with radiotherapy in preclinical models of glioblastoma, file e383531a-8144-15e8-e053-a505fe0a3de9
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134
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Increased levels of DNA methyltransferases are associated with the tumorigenic capacity of prostate cancer cells, file e3835320-856d-15e8-e053-a505fe0a3de9
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118
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Pharmacological targeting of the ephrin receptor kinase signalling by GLPG1790 in vitro and in vivo reverts oncophenotype, induces myogenic differentiation and radiosensitizes embryonal rhabdomyosarcoma cells, file e3835318-1f1d-15e8-e053-a505fe0a3de9
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117
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Testosterone insulin-like effects: an in vitro study on the short-term metabolic effects of testosterone in human skeletal muscle cells, file e383531c-907b-15e8-e053-a505fe0a3de9
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113
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The brain-penetrating CXCR4 antagonist, PRX177561, increases the antitumor effects of bevacizumab and sunitinib in preclinical models of human glioblastoma, file e3835320-871a-15e8-e053-a505fe0a3de9
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111
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Adjuvant radiation therapy in stage I seminoma: 20 years of oncologic results, file e383531c-2218-15e8-e053-a505fe0a3de9
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109
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Pharmacological treatment with inhibitors of nuclear export enhances the antitumor activity of docetaxel in human prostate cancer, file e3835320-88be-15e8-e053-a505fe0a3de9
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108
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Radiation therapy and serum salivary amylase in head and neck cancer, file e383531c-2e22-15e8-e053-a505fe0a3de9
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105
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Enhancement of radiosensitivity by the novel anticancer quinolone derivative vosaroxin in preclinical glioblastoma models, file e3835320-8722-15e8-e053-a505fe0a3de9
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104
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Correction to: The first-in-class alkylating deacetylase inhibitor molecule tinostamustine shows antitumor effects and is synergistic with radiotherapy in preclinical models of glioblastoma, file e383531c-19eb-15e8-e053-a505fe0a3de9
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103
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Bone control of muscle function, file e3835326-3ef9-15e8-e053-a505fe0a3de9
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101
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Defective DNA repair mechanisms in prostate cancer: impact of olaparib, file e3835318-6c94-15e8-e053-a505fe0a3de9
|
100
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The possible prognostic role of histone deacetylase and transforming growth factor β/Smad signaling in high grade gliomas treated by radio-chemotherapy: a preliminary immunohistochemical study, file e3835320-88b6-15e8-e053-a505fe0a3de9
|
98
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Key role of MEK/ERK pathway in sustaining tumorigenicity and in vitro radioresistance of embryonal rhabdomyosarcoma stem-like cell population, file e3835314-cdd5-15e8-e053-a505fe0a3de9
|
96
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Successful role of adjuvant radiotherapy in a rare case of tracheal inflammatory myofibroblastic tumor: a case report, file e3835321-4e45-15e8-e053-a505fe0a3de9
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93
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Induction chemotherapy followed by neoadjuvant chemoradiotherapy and surgery in locally advanced rectal cancer: preliminary results of a phase II study, file e3835322-9265-15e8-e053-a505fe0a3de9
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92
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Treatment of osteolytic solitary painful osseous metastases with radiofrequency ablation or cryoablation: a retrospective study by propensity analysis, file e3835314-d773-15e8-e053-a505fe0a3de9
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91
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Increased expression and activity of p75NTR are crucial events in azacitidine-induced cell death in prostate cancer, file e3835320-8716-15e8-e053-a505fe0a3de9
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91
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PARP inhibitors affect growth, survival and radiation susceptibility of human alveolar and embryonal rhabdomyosarcoma cell lines, file e3835324-605d-15e8-e053-a505fe0a3de9
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90
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Treatment of solitary painful osseous metastases with radiotherapy, cryoablation or combined therapy: propensity matching analysis in 175 patients, file e383531c-1c29-15e8-e053-a505fe0a3de9
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89
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Hypoxia sustains glioblastoma radioresistance through ERKs/DNA-PKcs/HIF-1α functional interplay, file e3835320-870a-15e8-e053-a505fe0a3de9
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89
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Episode-like pulse testosterone supplementation induces tumor senescence and growth arrest down-modulating androgen receptor through modulation of p-ERK1/2, pAR ser81 and CDK1 signaling: biological implications for men treated with testosterone replacement therapy, file e3835320-88c2-15e8-e053-a505fe0a3de9
|
80
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KPT-330, a potent and selective exportin-1 (XPO-1) inhibitor, shows antitumor effects modulating the expression of cyclin D1 and survivin [corrected] in prostate cancer models, file e3835320-8712-15e8-e053-a505fe0a3de9
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78
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Phenotypic characterization of human prostatic stromal cells in primary cultures derived from human tissue samples, file e3835320-8571-15e8-e053-a505fe0a3de9
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72
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Nerve growth factor regulation of cyclin D1 in PC12 cells through a p21 RAS extracellular signal-regulated kinase pathway requires cooperative interactions between Sp1 and nuclear factor-κB, file e3835320-8562-15e8-e053-a505fe0a3de9
|
71
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MiR-200c-3p contrasts PD-L1 induction by combinatorial therapies and slows proliferation of epithelial ovarian cancer through downregulation of β-Catenin and c-Myc, file e383532b-3cb1-15e8-e053-a505fe0a3de9
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68
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The brain penetrating and dual TORC1/TORC2 inhibitor, RES529, elicits anti-glioma activity and enhances the therapeutic effects of anti-angiogenetic compounds in preclinical murine models, file e3835324-f320-15e8-e053-a505fe0a3de9
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67
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Clinically relevant radioresistant rhabdomyosarcoma cell lines: functional, molecular and immune-related characterization, file e3835327-8cb0-15e8-e053-a505fe0a3de9
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64
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Antitumorigenic effects of inhibiting ephrin receptor kinase signaling by GLPG1790 against colorectal cancer cell lines In vitro and In vivo, file e3835326-8924-15e8-e053-a505fe0a3de9
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62
|
One-week vaginal brachytherapy schedule as exclusive adjuvant post-operative treatment in intermediate- and high-intermediate-risk endometrial cancer patients, file e3835326-e5d4-15e8-e053-a505fe0a3de9
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60
|
The Botanical Drug PBI-05204, a Supercritical CO2 Extract of Nerium Oleander, Inhibits Growth of Human Glioblastoma, Reduces Akt/mTOR Activities, and Modulates GSC Cell-Renewal Properties, file e383532b-cc71-15e8-e053-a505fe0a3de9
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57
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ATX-101, a peptide targeting PCNA, has antitumor efficacy alone or in combination with radiotherapy in murine models of human glioblastoma, file e383532e-581b-15e8-e053-a505fe0a3de9
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56
|
Muscle damage in systemic sclerosis and CXCL10: the potential therapeutic role of PDE5 inhibition, file e383532c-b132-15e8-e053-a505fe0a3de9
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54
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Dnmt3a and dnmt3b targeting as an effective radiosensitizing strategy in embryonal rhabdomyosarcoma, file e383532d-65da-15e8-e053-a505fe0a3de9
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53
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Oral platelet gel supernatant plus supportive medical treatment versus supportive medical treatment in the management of radiation-induced oral mucositis: a matched explorative active control trial by propensity analysis, file e3835322-ac5f-15e8-e053-a505fe0a3de9
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52
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The role of vaginal brachytherapy in stage I endometrial serous cancer. a systematic review, file e3835326-f3e8-15e8-e053-a505fe0a3de9
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52
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p21WAF1 expression induced by MEK/ERK pathway activation or inhibition correlates with growth arrest, myogenic differentiation and oncophenotype reversion in rhabdomyosarcoma cells, file e383531e-5c3c-15e8-e053-a505fe0a3de9
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51
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The small molecule ephrin receptor inhibitor, GLPG1790, Reduces renewal capabilities of cancer stem cells, showing anti-tumour efficacy on preclinical glioblastoma models, file e3835327-ccf7-15e8-e053-a505fe0a3de9
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49
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DNMT3B in vitro knocking-down is able to reverse embryonal rhabdomyosarcoma cell phenotype through inhibition of proliferation and induction of myogenic differentiation, file e3835321-8ff0-15e8-e053-a505fe0a3de9
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48
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OTX015 epi‐drug exerts antitumor effects in ovarian cancer cells by blocking GNL3‐mediated radioresistance mechanisms: cellular, molecular and computational evidence, file e383532c-2e46-15e8-e053-a505fe0a3de9
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47
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Toll-iike receptor-3 activation enhances malignant traits in human breast cancer cells through hypoxia-inducible factor-1α, file e3835329-b570-15e8-e053-a505fe0a3de9
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45
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Multiple antitumor molecular mechanisms are activated by a fully synthetic and stabilized pharmaceutical product delivering the active compound sulforaphane (SFX-01) in preclinical model of human glioblastoma, file e383532d-e968-15e8-e053-a505fe0a3de9
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45
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Biological rationale for targeting MEK/ERK pathways in anti-cancer therapy and to potentiate tumour responses to radiation, file e3835324-c33a-15e8-e053-a505fe0a3de9
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44
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Phosphodiesterase type-5 inhibitor tadalafil modulates steroid hormones signaling in a prostate cancer cell line, file e383532a-a359-15e8-e053-a505fe0a3de9
|
40
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Deep seated tumour treatments with electrons of high energy delivered at FLASH rates: the example of prostate cancer, file e383532d-bb13-15e8-e053-a505fe0a3de9
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34
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Radioresistance in rhabdomyosarcomas: much more than a question of dose, file 4b02e031-7b71-42c6-8b21-16272d58cfe8
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32
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Sulodexide counteracts endothelial dysfunction induced by metabolic or non-metabolic stresses through activation of the autophagic program, file e3835321-154c-15e8-e053-a505fe0a3de9
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28
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Treatment in locally advanced rectal cancer: a machine learning bibliometric analysis, file e383532d-e379-15e8-e053-a505fe0a3de9
|
24
|
MS−275 (Entinostat) promotes radio-sensitivity in PAX3-FOXO1 rhabdomyosarcoma cells, file e383532e-6f3c-15e8-e053-a505fe0a3de9
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17
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The botanical drug PBI-05204, a supercritical CO2 extract of Nerium oleander, sensitizes alveolar and embryonal rhabdomyosarcoma to radiotherapy in vitro and in vivo, file 0783418d-c4ef-4b0c-a036-6d27f4989a04
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16
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The botanical drug PBI-05204, a supercritical CO2 extract of nerium oleander, is synergistic with radiotherapy in models of human glioblastoma, file e383532f-1288-15e8-e053-a505fe0a3de9
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16
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Strategies for bone regeneration: from graft to tissue engineering, file e383532d-9641-15e8-e053-a505fe0a3de9
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15
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Cyclin D1 silencing suppresses tumorigenicity, impairs DNA double strand break repair and thus radiosensitizes androgenindependent prostate cancer cells to DNA damage, file e3835313-f960-15e8-e053-a505fe0a3de9
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14
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Anti‑oncogenic and pro‑myogenic action of the MKK6/p38/AKT axis induced by targeting MEK/ERK in embryonal rhabdomyosarcoma, file 350b77e5-4f3d-442a-b26a-d13c4c69d421
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13
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HDAC4 and HDAC6 sustain DNA double strand break repair and stem-like phenotype by promoting radioresistance in glioblastoma cells, file e3835316-b962-15e8-e053-a505fe0a3de9
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13
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MET inhibition sensitizes rhabdomyosarcoma cells to NOTCH signaling suppression, file e383532f-2608-15e8-e053-a505fe0a3de9
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13
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Abstract 6307: The botanical drug PBI-05204, a supercritical CO2 extract of Nerium oleander, augments the antitumor efficacy of radiotherapy in treatment of human glioblastoma, file 2b8d4af5-8966-48d3-a7f7-cc803a74321a
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11
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Translational implications for radiosensitizing strategies in rhabdomyosarcoma, file 73d8000b-e37d-4be9-aa68-f83d55343692
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10
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Torc1/Torc2 inhibitor, Palomid 529, enhances radiation response modulating CRM1-mediated survivin function and delaying DNA repair in prostate cancer models, file e3835312-60c5-15e8-e053-a505fe0a3de9
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9
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Adjuvant vaginal interventional radiotherapy in early-stage non-endometrioid carcinoma of corpus uteri: a systematic review, file e383532c-0883-15e8-e053-a505fe0a3de9
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9
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Spermine oxidase induces DNA damage and sensitizes fusion negative rhabdomyosarcoma cells to irradiation, file 08a12d05-1b43-45b6-868c-7ab7cc46d20c
|
8
|
Abscopal effect on bone metastases from solid tumors: a systematic review and retrospective analysis of challenge within a challenge, file 394e4e85-d746-428b-8f7d-1e282d0e092a
|
7
|
DNA damage response gene signature as potential treatment markers for oral squamous cell carcinoma, file c97b9767-f867-46de-8c3c-f4197aed5618
|
7
|
DNA repair in tumor radioresistance: insights from fruit flies genetics, file 22c5d224-ce6a-4e1b-ac54-a0bbb28f1dbf
|
6
|
Episode-like pulse testosterone supplementation induces tumor senescence and growth arrest down-modulating androgen receptor through modulation of p-ERK1/2, pAR ser81 and CDK1 signaling: biological implications for men treated with testosterone replacement therapy, file e383532b-20dd-15e8-e053-a505fe0a3de9
|
6
|
Safety and efficacy of combining afatinib and whole-brain radiation therapy in treating brain metastases from EGFR-mutated NSCLC: a case report and literature review, file f9ca6343-a14b-4502-8929-47a540f5264d
|
6
|
Radio-guided lung surgery: a feasible approach for a cancer precision medicine, file cb27663a-1dc0-4f53-8d3c-c5e5550305c2
|
5
|
ROCK2 and its alternatively spliced isoform ROCK2m positively control the maturation of the myogenic program, file e3835321-a18a-15e8-e053-a505fe0a3de9
|
5
|
Locally advanced rectal cancer. Treatment approach in elderly patients, file e3835325-0dbf-15e8-e053-a505fe0a3de9
|
5
|
The prostacyclin analogue Iloprost modulates CXCL10 in systemic sclerosis, file 6af333b6-06aa-4e55-bb7c-8a1c4e0ce262
|
4
|
Radioresistance Mechanisms in Prostate Cancer Cell Lines Surviving Ultra-Hypo-Fractionated EBRT: Implications and Possible Clinical Applications, file d90fcaf3-d59a-46d2-84ba-decd999c0216
|
4
|
Disruption of MEK/ERK/c-Myc signaling radiosensitizes prostate cancer cells in vitro and in vivo, file e383531b-2ea3-15e8-e053-a505fe0a3de9
|
4
|
Caveolin-1 enhances metastasis formation in a human model of embryonal rhabdomyosarcoma through Erk signaling cooperation, file e3835321-154e-15e8-e053-a505fe0a3de9
|
4
|
Romidepsin (FK228) fails in counteracting the transformed phenotype of rhabdomyosarcoma cells but efficiently radiosensitizes, in vitro and in vivo, the alveolar phenotype subtype, file 61b0939f-c9e2-44be-b18f-57c7d1c389e7
|
3
|
The first negative allosteric modulator for dopamine D2 and D3 receptors, SB269652 may lead to a new generation of antipsychotic drugs, file e3835320-871e-15e8-e053-a505fe0a3de9
|
3
|
Immune check-point in glioblastoma multiforme, file e3835321-3ea1-15e8-e053-a505fe0a3de9
|
3
|
NRF2 orchestrates the redox regulation induced by radiation therapy, sustaining embryonal and alveolar rhabdomyosarcoma cells radioresistance, file e3835321-4e4c-15e8-e053-a505fe0a3de9
|
3
|
Pro-differentiating and radiosensitizing effects of inhibiting HDACs by PXD-101 (Belinostat) in in vitro and in vivo models of human rhabdomyosarcoma cell lines, file e3835322-ac3e-15e8-e053-a505fe0a3de9
|
3
|
BET inhibition therapy counteracts cancer cell survival, clonogenic potential and radioresistance mechanisms in rhabdomyosarcoma cells, file e3835325-e073-15e8-e053-a505fe0a3de9
|
3
|
null, file e383532a-cc2e-15e8-e053-a505fe0a3de9
|
3
|
Clinical efficacy of adjuvant radiotherapy for WHO grade II intracranial meningioma, file 17eef732-b088-43c0-9c63-6ff13e870b77
|
2
|
Hyperactive Akt1 Signaling Increases Tumor Progression and DNA Repair in Embryonal Rhabdomyosarcoma RD Line and Confers Susceptibility to Glycolysis and Mevalonate Pathway Inhibitors, file 98433ab2-3583-4d02-bbb0-9f94e9db0bef
|
2
|
PXD101 potentiates hormonal therapy and prevents the onset of castration-resistant phenotype modulating androgen receptor, HSP90, and CRM1 in preclinical models of prostate cancer, file e3835313-c526-15e8-e053-a505fe0a3de9
|
2
|
c-Myc sustains transformed phenotype and promotes radioresistance of embryonal rhabdomyosarcoma cell lines, file e3835318-6b4b-15e8-e053-a505fe0a3de9
|
2
|
Vitamin D protects endothelial cells from irradiation-induced senescence and apoptosis by modulating MAPK/SirT1 axis, file e383531b-edbf-15e8-e053-a505fe0a3de9
|
2
|
Down-regulation of c-Myc following MEK/ERK inhibition halts the expression of malignant phenotype in rhabdomyosarcoma and in non muscle-derived human tumors, file e3835320-855e-15e8-e053-a505fe0a3de9
|
2
|
Dual PI3K/mTOR inhibitor, XL765 (SAR245409), shows superior effects to sole PI3K [XL147 (SAR245408)] or mTOR [rapamycin] inhibition in prostate cancer cell models, file e3835320-870e-15e8-e053-a505fe0a3de9
|
2
|
Histone deacetylase inhibitor ITF2357 (givinostat) reverts transformed phenotype and counteracts stemness in in vitro and in vivo models of human glioblastoma, file e3835321-1552-15e8-e053-a505fe0a3de9
|
2
|
Comparative study of testosterone and vitamin D analogue, elocalcitol, on insulin-controlled signal transduction pathway regulation in human skeletal muscle cells, file e3835321-43c4-15e8-e053-a505fe0a3de9
|
2
|
Dichlorodiphenyltrichloroethane, an old pesticide with a new mechanism of toxicity, file e3835321-cb08-15e8-e053-a505fe0a3de9
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2
|
Parkinson's disease and light: the bright and the dark sides, file e3835324-b6b5-15e8-e053-a505fe0a3de9
|
2
|
Are we ready for a paradigm shift from high-dose conventional to moderate hypofractionated radiotherapy in intermediate-high risk prostate cancer? A systematic review of randomized controlled trials with trial sequential analysis, file e3835324-d586-15e8-e053-a505fe0a3de9
|
2
|
Neurotoxic and neuroprotective role of exosomes in parkinson’s disease, file e3835324-ef3b-15e8-e053-a505fe0a3de9
|
2
|
Is a reduction of radiation dose feasible in patients affected by glioblastoma undergoing radio-chemotherapy according to MGMT promoter methylation status without jeopardizing survival?, file e3835324-f4c9-15e8-e053-a505fe0a3de9
|
2
|
Testosterone-mediated activation of androgenic signalling sustains in vitro the transformed and radioresistant phenotype of rhabdomyosarcoma cell lines, file e3835329-6330-15e8-e053-a505fe0a3de9
|
2
|
Totale |
4.863 |