BATTISTA, THEO
BATTISTA, THEO
DIPARTIMENTO DI SCIENZE BIOCHIMICHE "ALESSANDRO ROSSI FANELLI"
Anti-trypanosomatidal drug discovery: a challenge for structural biology
2020 Battista, Theo
Identification and characterization of the pyridoxal 5'-phosphate allosteric site in Escherichia coli pyridoxine 5'-phosphate oxidase
2021 Barile, Anna; Battista, Theo; Fiorillo, Annarita; Luigi di Salvo, Martino; Malatesta, Francesco; Tramonti, Angela; Ilari, Andrea; Contestabile, Roberto
Investigation of the Entry Pathway and Molecular Nature of σ1 Receptor Ligands
2023 Pascarella, Gianmarco; Antonelli, Lorenzo; Narzi, Daniele; Battista, Theo; Fiorillo, Annarita; Colotti, Gianni; Guidoni, Leonardo; Morea, Veronica; Ilari, Andrea
Known drugs identified by structure-based virtual screening are able to bind sigma-1 receptor and increase growth of huntington disease patient-derived cells
2021 Battista, T.; Pascarella, G.; Staid, D. S.; Colotti, G.; Rosati, J.; Fiorillo, A.; Casamassa, A.; Vescovi, A. L.; Giabbai, B.; Semrau, M. S.; Fanelli, S.; Storici, P.; Squitieri, F.; Morea, V.; Ilari, A.
Molecular bases of Sorcin-dependent resistance to chemotherapeutic agents
2018 Genovese, Ilaria; Ilari, Andrea; Battista, Theo; Chiarini, Valerio; Fazi, Francesco; Fiorillo, Annarita; Colotti, Gianni
Optimization of potent and specific trypanothione reductase inhibitors. A structure-based drug discovery approach
2022 Battista, T.; Federico, S.; Brogi, S.; Pozzetti, L.; Khan, T.; Butini, S.; Ramunno, A.; Fiorentino, E.; Orsini, S.; Di Muccio, T.; Fiorillo, A.; Exertier, C.; Di Risola, D.; Colotti, G.; Gemma, S.; Ilari, A.; Campiani, G.
Profiling calcium-dependent interactions between Sorcin and intrinsically disordered regions of human proteome
2020 Genovese, I.; Carotti, A.; Ilari, A.; Fiorillo, A.; Battista, T.; Colotti, G.; Ivarsson, Y.
Roles of sorcin in drug resistance in cancer: one protein, many mechanisms, for a novel potential anticancer drug target
2020 Battista, T.; Fiorillo, A.; Chiarini, V.; Genovese, I.; Ilari, A.; Colotti, G.
Sorcin is an early marker of neurodegeneration, Ca2+ dysregulation and endoplasmic reticulum stress associated to neurodegenerative diseases
2020 Genovese, I.; Giamogante, F.; Barazzuol, L.; Battista, T.; Fiorillo, A.; Vicario, M.; D'Alessandro, G.; Cipriani, R.; Limatola, C.; Rossi, D.; Sorrentino, V.; Poser, E.; Mosca, L.; Squitieri, F.; Perluigi, M.; Arena, A.; van Petegem, F.; Tito, C.; Fazi, F.; Giorgi, C.; Cali, T.; Ilari, A.; Colotti, G.
Spiro-containing derivatives show antiparasitic activity against trypanosoma brucei through inhibition of the trypanothione reductase enzyme
2020 Turcano, L.; Battista, T.; De Haro, E. T.; Missineo, A.; Alli, C.; Paonessa, G.; Colotti, G.; Harper, S.; Fiorillo, A.; Ilari, A.; Bresciani, A.
Structural basis of ubiquitination mediated by protein splicing in early Eukarya
2021 Chiarini, V.; Fiorillo, A.; Camerini, S.; Crescenzi, M.; Nakamura, S.; Battista, T.; Guidoni, L.; Colotti, G.; Ilari, A.
Structure-guided approach to identify a novel class of anti-leishmaniasis diaryl sulfide compounds targeting the trypanothione metabolism
2019 Colotti, G.; Saccoliti, F.; Gramiccia, M.; Di Muccio, T.; Prakash, J.; Yadav, S.; Dubey, V. K.; Vistoli, G.; Battista, T.; Mocci, S.; Fiorillo, A.; Bibi, Aasia; Madia, V. N.; Messore, A.; Costi, R.; Di Santo, R.; Ilari, A.
Targeting trypanothione reductase, a key enzyme in the redox trypanosomatid metabolism, to develop new drugs against leishmaniasis and trypanosomiases
2020 Battista, T.; Colotti, G.; Ilari, A.; Fiorillo, A.
The Met80Ala and Tyr67His/Met80Ala mutants of human cytochrome c shed light on the reciprocal role of Met80 and Tyr67 in regulating ligand access into the heme pocket
2017 Cervelli, Manuela; Mariottini, Paolo; Smulevich, Giulietta; Coletta, Massimo; Fiorucci, Laura; Battista, Theo
Toward a Drug Against All Kinetoplastids: From LeishBox to Specific and Potent Trypanothione Reductase Inhibitors
2018 Ilari, Andrea; Genovese, Ilaria; Fabiana, Fiorillo; Battista, Theo; Ilenia De Ionna, ; Fiorillo, Annarita; Colotti, Gianni
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| Anti-trypanosomatidal drug discovery: a challenge for structural biology | 2020 | Battista, Theo | |
| Identification and characterization of the pyridoxal 5'-phosphate allosteric site in Escherichia coli pyridoxine 5'-phosphate oxidase | 2021 | Barile, Anna; Battista, Theo; Fiorillo, Annarita; Luigi di Salvo, Martino; Malatesta, Francesco; Tramonti, Angela; Ilari, Andrea; Contestabile, Roberto | |
| Investigation of the Entry Pathway and Molecular Nature of σ1 Receptor Ligands | 2023 | Pascarella, Gianmarco; Antonelli, Lorenzo; Narzi, Daniele; Battista, Theo; Fiorillo, Annarita; Colotti, Gianni; Guidoni, Leonardo; Morea, Veronica; Ilari, Andrea | |
| Known drugs identified by structure-based virtual screening are able to bind sigma-1 receptor and increase growth of huntington disease patient-derived cells | 2021 | Battista, T.; Pascarella, G.; Staid, D. S.; Colotti, G.; Rosati, J.; Fiorillo, A.; Casamassa, A.; Vescovi, A. L.; Giabbai, B.; Semrau, M. S.; Fanelli, S.; Storici, P.; Squitieri, F.; Morea, V.; Ilari, A. | |
| Molecular bases of Sorcin-dependent resistance to chemotherapeutic agents | 2018 | Genovese, Ilaria; Ilari, Andrea; Battista, Theo; Chiarini, Valerio; Fazi, Francesco; Fiorillo, Annarita; Colotti, Gianni | |
| Optimization of potent and specific trypanothione reductase inhibitors. A structure-based drug discovery approach | 2022 | Battista, T.; Federico, S.; Brogi, S.; Pozzetti, L.; Khan, T.; Butini, S.; Ramunno, A.; Fiorentino, E.; Orsini, S.; Di Muccio, T.; Fiorillo, A.; Exertier, C.; Di Risola, D.; Colotti, G.; Gemma, S.; Ilari, A.; Campiani, G. | |
| Profiling calcium-dependent interactions between Sorcin and intrinsically disordered regions of human proteome | 2020 | Genovese, I.; Carotti, A.; Ilari, A.; Fiorillo, A.; Battista, T.; Colotti, G.; Ivarsson, Y. | |
| Roles of sorcin in drug resistance in cancer: one protein, many mechanisms, for a novel potential anticancer drug target | 2020 | Battista, T.; Fiorillo, A.; Chiarini, V.; Genovese, I.; Ilari, A.; Colotti, G. | |
| Sorcin is an early marker of neurodegeneration, Ca2+ dysregulation and endoplasmic reticulum stress associated to neurodegenerative diseases | 2020 | Genovese, I.; Giamogante, F.; Barazzuol, L.; Battista, T.; Fiorillo, A.; Vicario, M.; D'Alessandro, G.; Cipriani, R.; Limatola, C.; Rossi, D.; Sorrentino, V.; Poser, E.; Mosca, L.; Squitieri, F.; Perluigi, M.; Arena, A.; van Petegem, F.; Tito, C.; Fazi, F.; Giorgi, C.; Cali, T.; Ilari, A.; Colotti, G. | |
| Spiro-containing derivatives show antiparasitic activity against trypanosoma brucei through inhibition of the trypanothione reductase enzyme | 2020 | Turcano, L.; Battista, T.; De Haro, E. T.; Missineo, A.; Alli, C.; Paonessa, G.; Colotti, G.; Harper, S.; Fiorillo, A.; Ilari, A.; Bresciani, A. | |
| Structural basis of ubiquitination mediated by protein splicing in early Eukarya | 2021 | Chiarini, V.; Fiorillo, A.; Camerini, S.; Crescenzi, M.; Nakamura, S.; Battista, T.; Guidoni, L.; Colotti, G.; Ilari, A. | |
| Structure-guided approach to identify a novel class of anti-leishmaniasis diaryl sulfide compounds targeting the trypanothione metabolism | 2019 | Colotti, G.; Saccoliti, F.; Gramiccia, M.; Di Muccio, T.; Prakash, J.; Yadav, S.; Dubey, V. K.; Vistoli, G.; Battista, T.; Mocci, S.; Fiorillo, A.; Bibi, Aasia; Madia, V. N.; Messore, A.; Costi, R.; Di Santo, R.; Ilari, A. | |
| Targeting trypanothione reductase, a key enzyme in the redox trypanosomatid metabolism, to develop new drugs against leishmaniasis and trypanosomiases | 2020 | Battista, T.; Colotti, G.; Ilari, A.; Fiorillo, A. | |
| The Met80Ala and Tyr67His/Met80Ala mutants of human cytochrome c shed light on the reciprocal role of Met80 and Tyr67 in regulating ligand access into the heme pocket | 2017 | Cervelli, Manuela; Mariottini, Paolo; Smulevich, Giulietta; Coletta, Massimo; Fiorucci, Laura; Battista, Theo | |
| Toward a Drug Against All Kinetoplastids: From LeishBox to Specific and Potent Trypanothione Reductase Inhibitors | 2018 | Ilari, Andrea; Genovese, Ilaria; Fabiana, Fiorillo; Battista, Theo; Ilenia De Ionna, ; Fiorillo, Annarita; Colotti, Gianni |