| Nome |
# |
|
Targeting GLI factors to inhibit the Hedgehog pathway, file e3835314-c0cb-15e8-e053-a505fe0a3de9
|
409
|
|
Synergistic inhibition of the Hedgehog pathway by newly designed Smo and Gli antagonists bearing the isoflavone scaffold, file e383531b-2db6-15e8-e053-a505fe0a3de9
|
329
|
|
A unique high-diversity natural product collection as a reservoir of new therapeutic leads, file e383532a-e668-15e8-e053-a505fe0a3de9
|
298
|
|
Design and synthesis of piperazine-based compounds conjugated to humanized ferritin as delivery system of siRNA in cancer cells, file e383532c-583a-15e8-e053-a505fe0a3de9
|
248
|
|
IR ion spectroscopy in a combined approach with MS/MS and IM-MS to discriminate epimeric anthocyanin glycosides (cyanidin 3-O-glucoside and -galactoside), file e3835322-e087-15e8-e053-a505fe0a3de9
|
226
|
|
Inhibition of Hedgehog-dependent tumors and cancer stem cells by a newly identified naturally occurring chemotype, file e3835315-822b-15e8-e053-a505fe0a3de9
|
198
|
|
Yeast as a tool to select inhibitors of the cullin deneddylating enzyme Csn5, file e3835314-a1c0-15e8-e053-a505fe0a3de9
|
196
|
|
Site-directed antibody immobilization by resorc[4]arene-based immunosensors, file e3835326-914e-15e8-e053-a505fe0a3de9
|
183
|
|
The therapeutic aspects of the endocannabinoid system (ECS) for cancer and their development: from nature to laboratory, file e3835321-9e58-15e8-e053-a505fe0a3de9
|
176
|
|
The revaluation of plant-derived terpenes to fight antibiotic-resistant Infections, file e3835326-bf63-15e8-e053-a505fe0a3de9
|
147
|
|
In Memory of Maurizio Botta: his Contribution to the Development of Computer-Aided Drug Design, file e3835326-e70b-15e8-e053-a505fe0a3de9
|
133
|
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1H-NMR metabolomics reveals the Glabrescione B exacerbation of glycolytic metabolism beside the cell growth inhibitory effect in glioma, file e3835324-64ee-15e8-e053-a505fe0a3de9
|
129
|
|
Statins interfere with the attachment of S. cerevisiae mtDNA to the inner mitochondrial membrane, file e3835323-9f26-15e8-e053-a505fe0a3de9
|
125
|
|
Identification of a novel chalcone derivative that inhibits Notch signaling in T-cell acute lymphoblastic leukemia, file e383531a-2132-15e8-e053-a505fe0a3de9
|
122
|
|
Oregonin from Alnus incana bark affects DNA methyltransferases expression and mitochondrial DNA copies in mouse embryonic fibroblasts, file e383531b-5719-15e8-e053-a505fe0a3de9
|
115
|
|
Naturally-occurring alkaloids of plant origin as potential antimicrobials against antibiotic-resistant infections, file e3835327-7dd3-15e8-e053-a505fe0a3de9
|
112
|
|
A Smo/Gli multitarget hedgehog pathway inhibitor impairs tumor growth, file e3835323-769e-15e8-e053-a505fe0a3de9
|
110
|
|
A multimethodological characterization of Cannabis sativa L. inflorescences from seven dioecious cultivars grown in Italy: the effect of different harvesting stages, file e383532c-6fb1-15e8-e053-a505fe0a3de9
|
109
|
|
Synthesis, biological evaluation and molecular modeling studies on novel quinonoid inhibitors of CDC25 phosphatases, file e3835321-6012-15e8-e053-a505fe0a3de9
|
105
|
|
Anti-Candida albicans biofilm activity of extracts from two selected indigenous Algerian plants. Clematis flammula and Fraxinus angustifolia, file e3835328-6dad-15e8-e053-a505fe0a3de9
|
89
|
|
Chalcones and chalcone-mimetic derivatives as Notch inhibitors in a model of T-cell Acute Lymphoblastic Leukemia, file e383532a-26ed-15e8-e053-a505fe0a3de9
|
88
|
|
Nigritanine as a new potential antimicrobial alkaloid for the treatment of Staphylococcus aureus-induced infections, file e3835323-40a8-15e8-e053-a505fe0a3de9
|
77
|
|
Green routes for the production of enantiopure benzylisoquinoline alkaloids, file e3835321-bce8-15e8-e053-a505fe0a3de9
|
76
|
|
Cannabis sativa L. inflorescences from monoecious cultivars grown in central Italy: an untargeted chemical characterization from early flowering to ripening, file e3835325-dfbd-15e8-e053-a505fe0a3de9
|
74
|
|
Gli1/DNA interaction is a druggable target for Hedgehog-dependent tumors, file e3835312-4876-15e8-e053-a505fe0a3de9
|
70
|
|
Glabrescione B delivery by self-assembling micelles efficiently inhibits tumor growth in preclinical models of Hedgehog-dependent medulloblastoma, file e3835328-eb23-15e8-e053-a505fe0a3de9
|
65
|
|
The Pictet-Spengler reaction updates its habits, file e3835325-b951-15e8-e053-a505fe0a3de9
|
63
|
|
A novel colistin adjuvant identified by virtual screening for ArnT inhibitors, file e3835327-7506-15e8-e053-a505fe0a3de9
|
62
|
|
Stable oxidative cytosine modifications accumulate in cardiac mesenchymal cells from Type2 diabetes patients: Rescue by α-ketoglutarate and TET-TDG functional reactivation, file e3835321-b173-15e8-e053-a505fe0a3de9
|
55
|
|
Neuro‐signals from gut microbiota: perspectives for brain glioma, file e383532c-a0ed-15e8-e053-a505fe0a3de9
|
52
|
|
Nuclear Factor of Activated T Cells-dependent Down-regulation of the Transcription Factor Glioma-associated Protein 1 (GLI1) Underlies the Growth Inhibitory Properties of Arachidonic Acid, file e3835315-bc09-15e8-e053-a505fe0a3de9
|
48
|
|
Dual smo/braf inhibition by flavonolignans from silybum marianum, file e383532c-a42d-15e8-e053-a505fe0a3de9
|
48
|
|
Alvaxanthone, a thymidylate synthase inhibitor with nematocidal and tumoricidal activities, file e383532d-174a-15e8-e053-a505fe0a3de9
|
42
|
|
Active components from Cassia abbreviata prevent hiv-1 entry by distinct mechanisms of action, file e383532c-800d-15e8-e053-a505fe0a3de9
|
37
|
|
Sempervirine inhibits RNA polymerase I transcription independently from p53 in tumor cells, file e383532d-615b-15e8-e053-a505fe0a3de9
|
37
|
|
Esc peptides as novel potentiators of defective cystic fibrosis transmembrane conductance regulator: an unprecedented property of antimicrobial peptides, file e383532e-4eeb-15e8-e053-a505fe0a3de9
|
37
|
|
Rational design and synthesis of a novel BODIPY-based probe for selective imaging of tau tangles in human iPSC-derived cortical neurons, file e383532e-ae62-15e8-e053-a505fe0a3de9
|
36
|
|
The triprenylated anthranoid Ferruginin A, a promising scaffold for the development of novel antibiotics against Gram-positive bacteria, file e383532e-4504-15e8-e053-a505fe0a3de9
|
34
|
|
Chapter 5. NMR methodologies in food analysis, file e3835325-9898-15e8-e053-a505fe0a3de9
|
31
|
|
Natural cannabichromene (CBC) shows distinct scalemicity grades and enantiomeric dominance in cannabis sativa strains, file 528b0d00-eb6a-425f-b3cd-aba5c19fd139
|
30
|
|
NMR applications in food analysis. Part B, file e3835325-987d-15e8-e053-a505fe0a3de9
|
22
|
|
Chapter 6. NMR applications in food analysis: part A, file e3835325-da2e-15e8-e053-a505fe0a3de9
|
21
|
|
Design and synthesis of new withaferin A inspired hedgehog pathway inhibitors, file e383532e-9365-15e8-e053-a505fe0a3de9
|
18
|
|
A multi-methodological approach in the study of Italian PDO “Cornetto di Pontecorvo” red sweet pepper, file e3835319-f985-15e8-e053-a505fe0a3de9
|
17
|
|
Natural Flavonoid Derivatives Have Pan-Coronavirus Antiviral Activity, file 2161931d-7a0b-4e99-b019-4a3d6dcd5e86
|
15
|
|
Editorial: Secondary metabolites and peptides as unique natural reservoirs of new therapeutic leads for treatment of cancer and microbial infections, file e383532d-6594-15e8-e053-a505fe0a3de9
|
14
|
|
Yeast as a tool to select inhibitors of the cullin deneddylating enzyme Csn5, file e3835314-a901-15e8-e053-a505fe0a3de9
|
9
|
|
Structural elucidation and antimicrobial characterization of novel diterpenoids from Fabiana densa var. ramulosa, file e3835326-1221-15e8-e053-a505fe0a3de9
|
9
|
|
Reaction of Nitrosonium Cation with Resorc[4]arenes Activated by Supramolecular Control: Covalent Bond Formation, file e3835312-3123-15e8-e053-a505fe0a3de9
|
8
|
|
NMR applications in food analysis. Part B, file e3835325-e399-15e8-e053-a505fe0a3de9
|
8
|
|
Discovery of Mycobacterium tuberculosis Protein Tyrosine Phosphatase B (PtpB) Inhibitors from Natural Products, file e3835312-4d72-15e8-e053-a505fe0a3de9
|
7
|
|
Synthesis of a Double-Spanned Resorc[4]arene via Ring-Closing Metathesis and Calculation of Aggregation Propensity, file e3835312-6dea-15e8-e053-a505fe0a3de9
|
7
|
|
Hydrolytic inhibition of α-chymotrypsin by 2,8,14,20-tetrakis(D-leucyl-D-valinamido)resorc[4]arenecarboxylic acid: a spectroscopic NMR and computational combined approach, file e3835312-cc1d-15e8-e053-a505fe0a3de9
|
7
|
|
Naturally occurring Diels-Alder-type adducts from Morus nigra as potent inhibitors of Mycobacterium tuberculosis protein tyrosine phosphatase B, file e3835321-8266-15e8-e053-a505fe0a3de9
|
7
|
|
From Macrocycles to Molecular Shuttles: Exploring the Supramolecular Assembly of Resorc[4]arenes., file e383532c-59c6-15e8-e053-a505fe0a3de9
|
7
|
|
Stereochemical Preference of 2'-Deoxycytidine for Chiral Bis(diamido)-bridged Basket Resorcin[4]arenes, file e3835312-3190-15e8-e053-a505fe0a3de9
|
6
|
|
Design, palladium-catalyzed synthesis, and biological investigation of 2-substituted 3-aroylquinolin-4(1H)-ones as inhibitors of the Hedgehog signaling pathway., file e383531d-c1a3-15e8-e053-a505fe0a3de9
|
6
|
|
Olefin metathesis reaction as a locking tool for macrocycle and mechanomolecule construction, file e3835321-e45e-15e8-e053-a505fe0a3de9
|
6
|
|
Ent-beyerane diterpenes as a key platform for the development of arnt-mediated colistin resistance inhibitors, file e3835328-0c0f-15e8-e053-a505fe0a3de9
|
6
|
|
FROM MACROCYCLES TO MOLECULAR SHUTTLES: EXPLORING THE SUPRAMOLECULAR ASSEMBLY OF RESORC[4]ARENES, file e383532c-a04d-15e8-e053-a505fe0a3de9
|
6
|
|
Gas-Phase Enantioselective Reactions in Noncovalent Ion-Molecule Complexes, file e3835311-8ea4-15e8-e053-a505fe0a3de9
|
5
|
|
Cavity effects on the enantioselectivity of chiral amido[4]resorcinarene stereoisomers, file e3835311-a4e7-15e8-e053-a505fe0a3de9
|
5
|
|
New promising compounds with in vitro
nanomolar activity against Trypanosoma cruzi, file e3835312-4067-15e8-e053-a505fe0a3de9
|
5
|
|
NMR Characterization of Carboxymethyl Scleroglucan, file e3835312-4d79-15e8-e053-a505fe0a3de9
|
5
|
|
Covalently assembled resorcin[4]arenes and molecular tweezers: a chiral recognition rationale by NMR, file e3835320-ce7d-15e8-e053-a505fe0a3de9
|
5
|
|
A promising natural product, pristimerin, results in cytotoxicity against breast cancer stem cells in vitro and xenografts in vivo through apoptosis and an incomplete autopaghy in breast cancer, file e3835321-5fc6-15e8-e053-a505fe0a3de9
|
5
|
|
Chapter 6. NMR applications in food analysis: part A, file e3835325-da2d-15e8-e053-a505fe0a3de9
|
5
|
|
Total Synthesis of (±)-Kuwanol E, file a2810c5f-efa7-4d2e-8ed2-25ece06d133e
|
4
|
|
Chemical, computational and functional insights into the chemical stability of the Hedgehog pathway inhibitor GANT61, file d26acd5c-3127-444f-b143-51c8ec31320d
|
4
|
|
A high-throughput screening of a chemical compound library in ovarian cancer stem cells, file e383531e-0fb0-15e8-e053-a505fe0a3de9
|
4
|
|
Novel coumarin- and quinolinone-based polycycles as cell division cycle 25-A and -C phosphatases inhibitors induce proliferation arrest and apoptosis in cancer cells, file e383531e-72ea-15e8-e053-a505fe0a3de9
|
4
|
|
Hedgehog signaling pathway inhibitors: an updated patent review (2015–present), file e3835325-7707-15e8-e053-a505fe0a3de9
|
4
|
|
Synergistic inhibition of the Hedgehog pathway by newly designed Smo and Gli antagonists bearing the isoflavone scaffold, file e383532c-8b2d-15e8-e053-a505fe0a3de9
|
4
|
|
Click reaction as a tool to combine pharmacophores: The case of Vismodegib, file e3835314-c6c9-15e8-e053-a505fe0a3de9
|
3
|
|
Kuwanon-L as a new allosteric HIV-1 integrase inhibitor: molecular modeling and biological evaluation, file e3835321-c1b0-15e8-e053-a505fe0a3de9
|
3
|
|
Site-directed antibody immobilization by resorc[4]arene-based immunosensors, file e3835327-6d6d-15e8-e053-a505fe0a3de9
|
3
|
|
A novel enzymatic strategy for the synthesis of substituted tetrahydroisoquinolines, file e3835329-e0e1-15e8-e053-a505fe0a3de9
|
3
|
|
Calixarene: a versatile scaffold for the development of highly sensitive biosensors, file e383532d-9c2f-15e8-e053-a505fe0a3de9
|
3
|
|
Identification of effective anticancer g-quadruplex-targeting chemotypes through the exploration of a high diversity library of natural compounds, file e383532d-a414-15e8-e053-a505fe0a3de9
|
3
|
|
Resorc[4]arene-functionalized MWCNTS for the development of new highly sensitive immunosensors, file 3f0eea48-e8aa-4e7d-8455-c0f36c428428
|
2
|
|
Synthesis, Biosynthesis, and Biological Activity of Diels–Alder Adducts from Morus Genus: An Update, file 55ab95c4-94b8-4064-ac99-2f395a5ba645
|
2
|
|
Resorc[4]arene-functionalized MWCNTS for the development of new highly sensitive immunosensors, file c5db7174-dc6d-46af-9a16-1db87e70b27e
|
2
|
|
Use of elexacaftor/tezacaftor/ivacaftor combination in pregnancy, file d731ba69-5d43-4dbc-9026-7688c470182b
|
2
|
|
Exploring the potential of anthraquinone-based hybrids for identifying a novel generation of antagonists for the Smoothened receptor in HH-dependent tumour, file db979285-ff8c-4b0c-8812-33f7653c5d1a
|
2
|
|
Norcoclaurine Synthase: Mechanism of an Enantioselective Pictet-Spengler Catalyzing Enzyme, file e3835311-c707-15e8-e053-a505fe0a3de9
|
2
|
|
Undecenyl resorc[4]arene in the chair conformation as preorganized synthon for olefin metathesis, file e3835311-cf1f-15e8-e053-a505fe0a3de9
|
2
|
|
null, file e383531c-7aea-15e8-e053-a505fe0a3de9
|
2
|
|
Chapter 5. NMR methodologies in food analysis, file e383531f-6bbf-15e8-e053-a505fe0a3de9
|
2
|
|
Histone demethylating agents as potential S-adenosyl-l-methionine-competitors, file e3835322-0d86-15e8-e053-a505fe0a3de9
|
2
|
|
One hundred faces of cyclopamine, file e3835322-1d9f-15e8-e053-a505fe0a3de9
|
2
|
|
P300/CBP-associated factor regulates transcription and function of isocitrate dehydrogenase 2 during muscle differentiation, file e3835322-3dbc-15e8-e053-a505fe0a3de9
|
2
|
|
Improved identification of phytocannabinoids using a dedicated structure-based workflow, file e3835327-3949-15e8-e053-a505fe0a3de9
|
2
|
|
Synergistic inhibition of the Hedgehog pathway by newly designed Smo and Gli antagonists bearing the isoflavone scaffold, file e383532c-9839-15e8-e053-a505fe0a3de9
|
2
|
|
Δ9-cis-Tetrahydrocannabinol: Natural Occurrence, Chirality, and Pharmacology, file e383532c-aa88-15e8-e053-a505fe0a3de9
|
2
|
|
Exploring the assembly of resorc[4]arenes for the construction of supramolecular nano-aggregates, file e383532d-4784-15e8-e053-a505fe0a3de9
|
2
|
|
Flattened cone 2,8,14,20-tetrakis(L-valinamido)[4]resorcinarene: An enantioselective allosteric receptor in the gas phase, file e3835311-787e-15e8-e053-a505fe0a3de9
|
1
|
|
Antioxidant Properties of Aminoethylcysteine Ketimine Decarboxylated Dimer: A Review, file e3835312-c9f7-15e8-e053-a505fe0a3de9
|
1
|
|
Polymeric glabrescione B nanocapsules for passive targeting of Hedgehog-dependent tumor therapy in vitro, file e3835316-ae13-15e8-e053-a505fe0a3de9
|
1
|
|
Exploring oxidovanadium(IV) complexes as YopH inhibitors: mechanism of action and modeling studies, file e383531f-4d5d-15e8-e053-a505fe0a3de9
|
1
|
|
Potent human dihydroorotate dehydrogenase inhibitory activity of new quinoline-4-carboxylic acids derived from phenolic aldehydes: synthesis, cytotoxicity, lipophilicity and molecular docking studies, file e3835329-fd1a-15e8-e053-a505fe0a3de9
|
1
|
| Totale |
4.941 |