Sfoglia per Autore
Detrimental effects of the 'bath salt' methylenedioxypyrovalerone on social play behavior in male rats
2020 Schiavi, Sara; Melancia, Francesca; Carbone, Emilia; Buzzelli, Valeria; Manduca, Antonia; Peinado, Patricia Jiménez; Zwergel, Clemens; Mai, Antonello; Campolongo, Patrizia; Vanderschuren, Louk J M J; Trezza, Viviana
Discovery of the first human arylsulfatase a reversible inhibitor impairing mouse oocyte fertilization
2020 Caroselli, Silvia; Zwergel, Clemens; Pirolli, Adele; Sabatino, Manuela; Xu, Zhanjie; Kirsch, Gilbert; Mai, Antonello; Colotti, Gianni; Altieri, Fabio; Canipari, Rita; Valente, Sergio; Ragno, Rino
Design of first-in-class dual EZH2/HDAC inhibitor: biochemical activity and biological evaluation in cancer cells
2020 Romanelli, Annalisa; Stazi, Giulia; Fioravanti, Rossella; Zwergel, Clemens; Di Bello, Elisabetta; Pomella, Silvia; Perrone, Clara; Battistelli, Cecilia; Strippoli, Raffaele; Tripodi, Marco; del Bufalo, Donatella; Rota, Rossella; Trisciuoglio, Daniela; Mai, Antonello; Valente, Sergio
Novel quinoline compounds active in cancer cells through coupled DNA methyltransferase inhibition and degradation
2020 Zwergel, C.; Fioravanti, R.; Stazi, G.; Sarno, F.; Battistelli, C.; Romanelli, A.; Nebbioso, A.; Mendes, E.; Paulo, A.; Strippoli, R.; Tripodi, M.; Pechalrieu, D.; Arimondo, P. B.; De Luca, T.; Del Bufalo, D.; Trisciuoglio, D.; Altucci, L.; Valente, S.; Mai, A.
Tranylcypromine-based LSD1 inhibitors: structure-activity relationships, antiproliferative effects in leukemia, and gene target modulation
2020 Fioravanti, R.; Romanelli, A.; Mautone, N.; Di Bello, E.; Rovere, A.; Corinti, D.; Zwergel, C.; Valente, S.; Rotili, D.; Botrugno, O. A.; Dessanti, P.; Vultaggio, S.; Vianello, P.; Cappa, A.; Binda, C.; Mattevi, A.; Minucci, S.; Mercurio, C.; Varasi, M.; Mai, A.
Sirtuin modulators: where are we now? A review of patents from 2015 to 2019
2020 Mautone, Nicola; Zwergel, Clemens; Mai, Antonello; Rotili, Dante
The innovative potential of statins in cancer: new targets for new therapies
2020 Di Bello, Elisabetta; Zwergel, Clemens; Mai, Antonello; Valente, Sergio
Sirtuins
2021 Zwergel, Clemens; Tomaselli, Daniela; Mai, Antonello
Sex-dependent effects of the drugs of abuse amphetamine and the smart drug 3,4-methylenedioxypyrovalerone on fear memory generalization in rats
2021 Riccardi, Eleonora; Blasi, Eleonora; Zwergel, Clemens; Mai, Antonello; Morena, Maria; Campolongo, Patrizia
Structure-Guided Development of Small-Molecule PRC2 Inhibitors Targeting EZH2–EED Interaction
2021 Du, Daohai; Xu, Dandan; Zhu, Licheng; Stazi, Giulia; Zwergel, Clemens; Liu, Yanli; Luo, Zhongyuan; Li, Yuanqing; Zhang, Yuanyuan; Zhu, Kongkai; Ding, Yiluan; Liu, Jingqiu; Fan, Shijie; Zhao, Kaiyan; Zhang, Naixia; Kong, Xiangqian; Jiang, Hualiang; Chen, Kaixian; Zhao, Kehao; Valente, Sergio; Min, Jinrong; Duan, Wenhu; Luo, Cheng
Novel Pyridine-Based Hydroxamates and 2'-Aminoanilides as Histone Deacetylase Inhibitors: Biochemical Profile and Anticancer Activity
2021 Zwergel, Clemens; Di Bello, Elisabetta; Fioravanti, Rossella; Conte, Mariarosaria; Nebbioso, Angela; Mazzone, Roberta; Brosch, Gerald; Mercurio, Ciro; Varasi, Mario; Altucci, Lucia; Valente, Sergio; Mai, Antonello
The innovative potential of selenium-containing agents for fighting cancer and viral infections
2021 Ali, W.; Benedetti, R.; Handzlik, J.; Zwergel, C.; Battistelli, C.
Polycomb repressive complex 2 modulation through the development of EZH2–EED interaction inhibitors and EED binders
2021 Tomassi, Stefano; Romanelli, Annalisa; Zwergel, Clemens; Valente, Sergio; Mai, Antonello
Amphetamine modulation of long-term object recognition memory in rats: influence of stress
2021 Colucci, Paola; Santori, Alessia; Romanelli, Luca; Zwergel, Clemens; Mai, Antonello; Scaccianoce, Sergio; Campolongo, Patrizia
m6A RNA methylation and beyond - the epigenetic machinery and potential treatment options
2021 Garbo, Sabrina; Zwergel, Clemens; Battistelli, Cecilia
Inhibition of PKCθ Improves Dystrophic Heart Phenotype and Function in a Novel Model of DMD Cardiomyopathy
2022 Morroni, Jacopo; Schirone, Leonardo; Valenti, Valentina; Zwergel, Clemens; Riera, Carles Sánchez; Valente, Sergio; Vecchio, Daniele; Schiavon, Sonia; Ragno, Rino; Mai, Antonello; Sciarretta, Sebastiano; Lozanoska-Ochser, Biliana; Bouchè, Marina
Potent and Specific Activators for Mitochondrial Sirtuins Sirt3 and Sirt5
2022 Suenkel, Benjamin; Valente, Sergio; Zwergel, Clemens; Weiss, Sandra; DI BELLO, Elisabetta; Fioravanti, Rossella; Aventaggiato, Michele; Amorim, João A.; Garg, Neha; Kumar, Surinder; Lombard, David B.; Hu, Tuo; Singh, Pankaj K.; Tafani, Marco; Palmeira, Carlos M.; Sinclair, David; Mai, Antonello; Steegborn, Clemens
Effects of Structurally Different HDAC Inhibitors against Trypanosoma cruzi, Leishmania, and Schistosoma mansoni
2022 Di Bello, Elisabetta; Noce, Beatrice; Fioravanti, Rossella; Zwergel, Clemens; Valente, Sergio; Rotili, Dante; Fianco, Giulia; Trisciuoglio, Daniela; Mourão, Marina M; Sales, Policarpo; Lamotte, Suzanne; Prina, Eric; Späth, Gerald F; Häberli, Cécile; Keiser, Jennifer; Mai, Antonello
Heterocycle-containing tranylcypromine derivatives endowed with high anti-LSD1 activity
2022 Fioravanti, Rossella; Rodriguez, Veronica; Caroli, Jonatan; Chianese, Ugo; Benedetti, Rosaria; Di Bello, Elisabetta; Noce, Beatrice; Zwergel, Clemens; Corinti, Davide; Viña, Dolores; Altucci, Lucia; Mattevi, Andrea; Valente, Sergio; Mai, Antonello
Restoration of WT1/miR-769-5p axis by HDAC1 inhibition promotes MMT reversal in mesenchymal-like mesothelial cells
2022 Bontempi, Giulio; Terri, Michela; Garbo, Sabrina; Montaldo, Claudia; Mariotti, Davide; Bordoni, Veronica; Valente, Sergio; Zwergel, Clemens; Mai, Antonello; Marchetti, Alessandra; Domenici, Alessandro; Menè, Paolo; Battistelli, Cecilia; Tripodi, Marco; Strippoli, Raffaele
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| Detrimental effects of the 'bath salt' methylenedioxypyrovalerone on social play behavior in male rats | 2020 | Schiavi, Sara; Melancia, Francesca; Carbone, Emilia; Buzzelli, Valeria; Manduca, Antonia; Peinado, Patricia Jiménez; Zwergel, Clemens; Mai, Antonello; Campolongo, Patrizia; Vanderschuren, Louk J M J; Trezza, Viviana | |
| Discovery of the first human arylsulfatase a reversible inhibitor impairing mouse oocyte fertilization | 2020 | Caroselli, Silvia; Zwergel, Clemens; Pirolli, Adele; Sabatino, Manuela; Xu, Zhanjie; Kirsch, Gilbert; Mai, Antonello; Colotti, Gianni; Altieri, Fabio; Canipari, Rita; Valente, Sergio; Ragno, Rino | |
| Design of first-in-class dual EZH2/HDAC inhibitor: biochemical activity and biological evaluation in cancer cells | 2020 | Romanelli, Annalisa; Stazi, Giulia; Fioravanti, Rossella; Zwergel, Clemens; Di Bello, Elisabetta; Pomella, Silvia; Perrone, Clara; Battistelli, Cecilia; Strippoli, Raffaele; Tripodi, Marco; del Bufalo, Donatella; Rota, Rossella; Trisciuoglio, Daniela; Mai, Antonello; Valente, Sergio | |
| Novel quinoline compounds active in cancer cells through coupled DNA methyltransferase inhibition and degradation | 2020 | Zwergel, C.; Fioravanti, R.; Stazi, G.; Sarno, F.; Battistelli, C.; Romanelli, A.; Nebbioso, A.; Mendes, E.; Paulo, A.; Strippoli, R.; Tripodi, M.; Pechalrieu, D.; Arimondo, P. B.; De Luca, T.; Del Bufalo, D.; Trisciuoglio, D.; Altucci, L.; Valente, S.; Mai, A. | |
| Tranylcypromine-based LSD1 inhibitors: structure-activity relationships, antiproliferative effects in leukemia, and gene target modulation | 2020 | Fioravanti, R.; Romanelli, A.; Mautone, N.; Di Bello, E.; Rovere, A.; Corinti, D.; Zwergel, C.; Valente, S.; Rotili, D.; Botrugno, O. A.; Dessanti, P.; Vultaggio, S.; Vianello, P.; Cappa, A.; Binda, C.; Mattevi, A.; Minucci, S.; Mercurio, C.; Varasi, M.; Mai, A. | |
| Sirtuin modulators: where are we now? A review of patents from 2015 to 2019 | 2020 | Mautone, Nicola; Zwergel, Clemens; Mai, Antonello; Rotili, Dante | |
| The innovative potential of statins in cancer: new targets for new therapies | 2020 | Di Bello, Elisabetta; Zwergel, Clemens; Mai, Antonello; Valente, Sergio | |
| Sirtuins | 2021 | Zwergel, Clemens; Tomaselli, Daniela; Mai, Antonello | |
| Sex-dependent effects of the drugs of abuse amphetamine and the smart drug 3,4-methylenedioxypyrovalerone on fear memory generalization in rats | 2021 | Riccardi, Eleonora; Blasi, Eleonora; Zwergel, Clemens; Mai, Antonello; Morena, Maria; Campolongo, Patrizia | |
| Structure-Guided Development of Small-Molecule PRC2 Inhibitors Targeting EZH2–EED Interaction | 2021 | Du, Daohai; Xu, Dandan; Zhu, Licheng; Stazi, Giulia; Zwergel, Clemens; Liu, Yanli; Luo, Zhongyuan; Li, Yuanqing; Zhang, Yuanyuan; Zhu, Kongkai; Ding, Yiluan; Liu, Jingqiu; Fan, Shijie; Zhao, Kaiyan; Zhang, Naixia; Kong, Xiangqian; Jiang, Hualiang; Chen, Kaixian; Zhao, Kehao; Valente, Sergio; Min, Jinrong; Duan, Wenhu; Luo, Cheng | |
| Novel Pyridine-Based Hydroxamates and 2'-Aminoanilides as Histone Deacetylase Inhibitors: Biochemical Profile and Anticancer Activity | 2021 | Zwergel, Clemens; Di Bello, Elisabetta; Fioravanti, Rossella; Conte, Mariarosaria; Nebbioso, Angela; Mazzone, Roberta; Brosch, Gerald; Mercurio, Ciro; Varasi, Mario; Altucci, Lucia; Valente, Sergio; Mai, Antonello | |
| The innovative potential of selenium-containing agents for fighting cancer and viral infections | 2021 | Ali, W.; Benedetti, R.; Handzlik, J.; Zwergel, C.; Battistelli, C. | |
| Polycomb repressive complex 2 modulation through the development of EZH2–EED interaction inhibitors and EED binders | 2021 | Tomassi, Stefano; Romanelli, Annalisa; Zwergel, Clemens; Valente, Sergio; Mai, Antonello | |
| Amphetamine modulation of long-term object recognition memory in rats: influence of stress | 2021 | Colucci, Paola; Santori, Alessia; Romanelli, Luca; Zwergel, Clemens; Mai, Antonello; Scaccianoce, Sergio; Campolongo, Patrizia | |
| m6A RNA methylation and beyond - the epigenetic machinery and potential treatment options | 2021 | Garbo, Sabrina; Zwergel, Clemens; Battistelli, Cecilia | |
| Inhibition of PKCθ Improves Dystrophic Heart Phenotype and Function in a Novel Model of DMD Cardiomyopathy | 2022 | Morroni, Jacopo; Schirone, Leonardo; Valenti, Valentina; Zwergel, Clemens; Riera, Carles Sánchez; Valente, Sergio; Vecchio, Daniele; Schiavon, Sonia; Ragno, Rino; Mai, Antonello; Sciarretta, Sebastiano; Lozanoska-Ochser, Biliana; Bouchè, Marina | |
| Potent and Specific Activators for Mitochondrial Sirtuins Sirt3 and Sirt5 | 2022 | Suenkel, Benjamin; Valente, Sergio; Zwergel, Clemens; Weiss, Sandra; DI BELLO, Elisabetta; Fioravanti, Rossella; Aventaggiato, Michele; Amorim, João A.; Garg, Neha; Kumar, Surinder; Lombard, David B.; Hu, Tuo; Singh, Pankaj K.; Tafani, Marco; Palmeira, Carlos M.; Sinclair, David; Mai, Antonello; Steegborn, Clemens | |
| Effects of Structurally Different HDAC Inhibitors against Trypanosoma cruzi, Leishmania, and Schistosoma mansoni | 2022 | Di Bello, Elisabetta; Noce, Beatrice; Fioravanti, Rossella; Zwergel, Clemens; Valente, Sergio; Rotili, Dante; Fianco, Giulia; Trisciuoglio, Daniela; Mourão, Marina M; Sales, Policarpo; Lamotte, Suzanne; Prina, Eric; Späth, Gerald F; Häberli, Cécile; Keiser, Jennifer; Mai, Antonello | |
| Heterocycle-containing tranylcypromine derivatives endowed with high anti-LSD1 activity | 2022 | Fioravanti, Rossella; Rodriguez, Veronica; Caroli, Jonatan; Chianese, Ugo; Benedetti, Rosaria; Di Bello, Elisabetta; Noce, Beatrice; Zwergel, Clemens; Corinti, Davide; Viña, Dolores; Altucci, Lucia; Mattevi, Andrea; Valente, Sergio; Mai, Antonello | |
| Restoration of WT1/miR-769-5p axis by HDAC1 inhibition promotes MMT reversal in mesenchymal-like mesothelial cells | 2022 | Bontempi, Giulio; Terri, Michela; Garbo, Sabrina; Montaldo, Claudia; Mariotti, Davide; Bordoni, Veronica; Valente, Sergio; Zwergel, Clemens; Mai, Antonello; Marchetti, Alessandra; Domenici, Alessandro; Menè, Paolo; Battistelli, Cecilia; Tripodi, Marco; Strippoli, Raffaele |
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