VENDRUSCOLO, MICHELE

VENDRUSCOLO, MICHELE  

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A metastable subproteome underlies inclusion formation in muscle proteinopathies 2019 Ciryam, P.; Antalek, M.; Cid, F.; Tartaglia, G. G.; Dobson, C. M.; Guettsches, A. -K.; Eggers, B.; Vorgerd, M.; Marcus, K.; Kley, R. A.; Morimoto, R. I.; Vendruscolo, M.; Weihl, C. C.
A rationally designed six-residue swap generates comparability in the aggregation behavior of α-synuclein and β-synuclein 2012 Roodveldt, C.; Andersson, A.; De Genst, E. J.; Labrador-Garrido, A.; Buell, A. K.; Dobson, C. M.; Tartaglia, G. G.; Vendruscolo, M.
A Relationship between mRNA Expression Levels and Protein Solubility in E. coli 2009 Tartaglia, G. G.; Pechmann, S.; Dobson, C. M.; Vendruscolo, M.
ALMOST: An all atom molecular simulation toolkit for protein structure determination 2014 Fu, B.; Sahakyan, A. B.; Camilloni, C.; Tartaglia, G. G.; Paci, E.; Caflisch, A.; Vendruscolo, M.; Cavalli, A.
Als mutations in FUS cause neuronal dysfunction and death in caenorhabditis elegans by a dominant gain-of-function mechanism 2012 Murakami, T.; Yang, S. -P.; Xie, L.; Kawano, T.; Fu, D.; Mukai, A.; Bohm, C.; Chen, F.; Robertson, J.; Suzuki, H.; Tartaglia, G. G.; Vendruscolo, M.; Schierle, G. S. K.; Chan, F. T. S.; Moloney, A.; Crowther, D.; Kaminski, C. F.; Zhen, M.; St George-Hyslop, P.
ALS/FTD mutation-induced phase transition of FUS liquid droplets and reversible hydrogels into irreversible hydrogels impairs RNP granule function 2015 Murakami, T.; Qamar, S.; Lin, J. Q.; Schierle, G. S. K.; Rees, E.; Miyashita, A.; Costa, A. R.; Dodd, R. B.; Chan, F. T. S.; Michel, C. H.; Kronenberg-Versteeg, D.; Li, Y.; Yang, S. -P.; Wakutani, Y.; Meadows, W.; Ferry, R. R.; Dong, L.; Tartaglia, G. G.; Favrin, G.; Lin, W. -L.; Dickson, D. W.; Zhen, M.; Ron, D.; Schmitt-Ulms, G.; Fraser, P. E.; Shneider, N. A.; Holt, C.; Vendruscolo, M.; Kaminski, C. F.; St George-Hyslop, P.
Amyloid-like aggregates sequester numerous metastable proteins with essential cellular functions 2011 Olzscha, H.; Schermann, S. M.; Woerner, A. C.; Pinkert, S.; Hecht, M. H.; Tartaglia, G. G.; Vendruscolo, M.; Hayer-Hartl, M.; Hartl, F. U.; Vabulas, R. M.
Characterisation of Amyloid Fibril Formation by Small Heat-shock Chaperone Proteins Human αA-, αB- and R120G αB-Crystallins 2007 Meehan, S.; Knowles, T. P. J.; Baldwin, A. J.; Smith, J. F.; Squires, A. M.; Clements, P.; Treweek, T. M.; Ecroyd, H.; Tartaglia, G. G.; Vendruscolo, M.; Macphee, C. E.; Dobson, C. M.; Carver, J. A.
Competition between Folding, Native-State Dimerisation and Amyloid Aggregation in β-Lactoglobulin 2009 Hamada, D.; Tanaka, T.; Tartaglia, G. G.; Pawar, A.; Vendruscolo, M.; Kawamura, M.; Tamura, A.; Tanaka, N.; Dobson, C. M.
Competition between Intramolecular and Intermolecular Interactions in an Amyloid-Forming Protein 2009 Routledge, K. E.; Tartaglia, G. G.; Platt, G. W.; Vendruscolo, M.; Radford, S. E.
Correlation between mRNA expression levels and protein aggregation propensities in subcellular localisations 2009 Tartaglia, G. G.; Vendruscolo, M.
Detection of early locomotor abnormalities in a Drosophila model of Alzheimer's disease 2011 Jahn, T. R.; Kohlhoff, K. J.; Scott, M.; Tartaglia, G. G.; Lomas, D. A.; Dobson, C. M.; Vendruscolo, M.; Crowther, D. C.
Effects of the known pathogenic mutations on the aggregation pathway of the amyloidogenic peptide of apolipoprotein A-I 2011 Raimondi, S.; Guglielmi, F.; Giorgetti, S.; Gaetano, S. D.; Arciello, A.; Monti, D. M.; Relini, A.; Nichino, D.; Doglia, S. M.; Natalello, A.; Pucci, P.; Mangione, P.; Obici, L.; Merlini, G.; Stoppini, M.; Robustelli, P.; Tartaglia, G. G.; Vendruscolo, M.; Dobson, C. M.; Piccoli, R.; Bellotti, V.
FUS Phase Separation Is Modulated by a Molecular Chaperone and Methylation of Arginine Cation-π Interactions 2018 Qamar, Seema; Wang, Guozhen; Randle, Suzanne J.; Ruggeri, Francesco Simone; Varela, Juan A.; Lin, Julie Qiaojin; Phillips, Emma C.; Miyashita, Akinori; Williams, Declan; Ströhl, Florian; Meadows, William; Ferry, Rodylyn; Dardov, Victoria J.; Tartaglia, Gian G.; Farrer, Lindsay A.; Kaminski Schierle, Gabriele S.; Kaminski, Clemens F.; Holt, Christine E.; Fraser, Paul E.; Schmitt-Ulms, Gerold; Klenerman, David; Knowles, Tuomas; Vendruscolo, Michele; St George-Hyslop, Peter
Homage to Chris Dobson 2019 Baum, J.; Chiti, F.; De Simone, A.; Knowles, T. P. J.; Kumita, J. R.; Radford, S. E.; Robinson, C. V.; Salvatella, X.; Valelli, K.; Vendruscolo, M.; Pastore, A.; Tartaglia, G. G.
Interactions in the native state of monellin, which play a protective role against aggregation 2011 Szczepankiewicz, O.; Cabaleiro-Lago, C.; Tartaglia, G. G.; Vendruscolo, M.; Hunter, T.; Hunter, G. J.; Nilsson, H.; Thulin, E.; Linse, S.
Intrinsic determinants of neurotoxic aggregate formation by the amyloid β peptide 2010 Brorsson, A. -C.; Bolognesi, B.; Tartaglia, G. G.; Shammas, S. L.; Favrin, G.; Watson, I.; Lomas, D. A.; Chiti, F.; Vendruscolo, M.; Dobson, C. M.; Crowther, D. C.; Luheshi, L. M.
Life on the edge: a link between gene expression levels and aggregation rates of human proteins 2007 Tartaglia, G. G.; Pechmann, S.; Dobson, C. M.; Vendruscolo, M.
Metastability of native proteins and the phenomenon of amyloid formation 2011 Baldwin, A. J.; Knowles, T. P. J.; Tartaglia, G. G.; Fitzpatrick, A. W.; Devlin, G. L.; Shammas, S. L.; Waudby, C. A.; Mossuto, M. F.; Meehan, S.; Gras, S. L.; Christodoulou, J.; Anthony-Cahill, S. J.; Barker, P. D.; Vendruscolo, M.; Dobson, C. M.
Molecular determinants of the aggregation behavior of α- and β-synuclein 2008 Rivers, R. C.; Kumita, J. R.; Tartaglia, G. G.; Dedmon, M. M.; Pawar, A.; Vendruscolo, M.; Dobson, C. M.; Christodoulou, J.