IACHETTINI, SARA
IACHETTINI, SARA
A basal level of DNA damage and telomere deprotection increases the sensitivity of cancer cells to G-quadruplex interactive compounds
2015 Salvati, Erica; Rizzo, Angela; Iachettini, Sara; Zizza, Pasquale; Cingolani, Chiara; D'Angelo, Carmen; Porru, Manuela; Mondello, Chiara; Aiello, Aurora; Farsetti, Antonella; Gilson, Eric; Leonetti, Carlo; Biroccio, Annamaria
Aromatic Core Extension in the Series of N-Cyclic Bay-Substituted Perylene G-Quadruplex Ligands: Increased Telomere Damage, Antitumor Activity, and Strong Selectivity for Neoplastic over Healthy Cells
2012 Marco, Franceschin; Angela, Rizzo; Casagrande, Valentina; Erica, Salvati; Alvino, Antonello; Altieri, Alessandro; Alina, Ciammaichella; Iachettini, Sara; Carlo, Leonetti; Ortaggi, Giancarlo; Manuela, Porru; Bianco, Armandodoriano; Annamaria, Biroccio
Erratum: Identification of novel RHPS4-derivative ligands with improved toxicological profiles and telomere-targeting activities (Journal of Experimental & Clinical Cancer Research (2014) 33 (81))
2015 Rizzo, Angela; Iachettini, Sara; Zizza, Pasquale; Cingolani, Chiara; Porru, Manuela; Artuso, Simona; Stevens, Malcolm; Hummersone, Marc; Biroccio, Annamaria; Salvati, Erica; Leonetti, Carlo
Evidence for G-quadruplex in the promoter of vegfr-2 and its targeting to inhibit tumor angiogenesis
2014 Salvati, E; Zizza, P; Rizzo, A; Iachettini, Sara; Cingolani, Chiara; D'Angelo, C; Porru, M; Randazzo, A; Pagano, B; Novellino, E; Pisanu, Me; Stoppacciaro, Antonella; Spinella, F; Bagnato, A; Gilson, E; Leonetti, C; Biroccio, A.
Identification of novel RHPS4-derivative ligands with improved toxicological profiles and telomere-targeting activities.
2014 Rizzo, A; Iachettini, Sara; Zizza, P; Cingolani, Chiara; Porru, M; Artuso, S; Stevens, M; Hummersone, M; Biroccio, A; Salvati, E; Leonetti, C.
Molecular mechanism and biological activity of G-quadruplex ligands, a new potential class of antitumoral agents
2016 Iachettini, Sara
N-Cyclic Bay-Substituted Perylene G-Quadruplex Ligands Have Selective Antiproliferative Effects on Cancer Cells and Induce Telomere Damage
2011 Casagrande, Valentina; Erica, Salvati; Alvino, Antonello; Bianco, Armandodoriano; Alina, Ciammaichella; C., Dangelo; GINNARI SATRIANI, Luca; Serrilli, ANNA MARIA; Iachettini, Sara; Carlo, Leonetti; Stephen, Neidle; Ortaggi, Giancarlo; Manuela, Porru; Angela, Rizzo; Marco, Franceschin; Annamaria, Biroccio
On and off-target effects of telomere uncapping G-quadruplex selective ligands based on pentacyclic acridinium salts.
2013 Iachettini, Sara; Stevens, Mf; Frigerio, M; Hummersone, Mg; Hutchinson, I; Garner, Tp; Searle, Ms; Wilson, Dw; Munde, M; Nanjunda, R; D'Angelo, C; Zizza, P; Rizzo, A; Cingolani, Chiara; De Cicco, F; Porru, M; D'Incalci, M; Leonetti, C; Biroccio, A; Salvati, E.
PARP1 is activated at telomeres upon G4 stabilization: possible target for telomere-based therapy.
2010 Salvati, E; Scarsella, M; Porru, M; Rizzo, A; Iachettini, Sara; Tentori, L; Graziani, G; D'Incalci, M; Stevens, Mf; Orlandi, A; Passeri, D; Gilson, E; Zupi, G; Leonetti, C; Biroccio, A.
Perylene and coronene derivatives binding to G-rich promoter oncogene sequences efficiently reduce their expression in cancer cells
2016 Micheli, Emanuela; Altieri, Alessandro; Cianni, Lorenzo; Cingolani, Chiara; Iachettini, Sara; Bianco, Armandodoriano; Leonetti, Carlo; Cacchione, Stefano; Biroccio, Annamaria; Franceschin, Marco; Rizzo, Angela
Selective targeting of cancer-related G-quadruplex structures by the natural compound dicentrine
2023 Platella, Chiara; Ghirga, Francesca; Musumeci, Domenica; Quaglio, Deborah; Zizza, Pasquale; Iachettini, Sara; D’Angelo, Carmen; Biroccio, Annamaria; Botta, Bruno; Mori, Mattia; Montesarchio, Daniela
Shooting for selective druglike G-quadruplex binders: evidence for telomeric DNA damage and tumor cell death.
2012 Cosconati, S; Rizzo, A; Trotta, R; Pagano, B; Iachettini, Sara; De Tito, S; Lauri, I; Fotticchia, I; Giustiniano, M; Marinelli, L; Giancola, C; Novellino, E; Biroccio, A; Randazzo, A.
Tibialis anterior muscle needle biopsy and sensitive biomolecular methods: A useful tool in myotonic dystrophy type 1
2015 Iachettini, Sara; Valaperta, R.; Marchesi, Andrea; Perfetti, A.; Cuomo, G.; Fossati, B.; Vaienti, L.; Costa, E.; Meola, G.; Cardani, Rosanna
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| A basal level of DNA damage and telomere deprotection increases the sensitivity of cancer cells to G-quadruplex interactive compounds | 2015 | Salvati, Erica; Rizzo, Angela; Iachettini, Sara; Zizza, Pasquale; Cingolani, Chiara; D'Angelo, Carmen; Porru, Manuela; Mondello, Chiara; Aiello, Aurora; Farsetti, Antonella; Gilson, Eric; Leonetti, Carlo; Biroccio, Annamaria | |
| Aromatic Core Extension in the Series of N-Cyclic Bay-Substituted Perylene G-Quadruplex Ligands: Increased Telomere Damage, Antitumor Activity, and Strong Selectivity for Neoplastic over Healthy Cells | 2012 | Marco, Franceschin; Angela, Rizzo; Casagrande, Valentina; Erica, Salvati; Alvino, Antonello; Altieri, Alessandro; Alina, Ciammaichella; Iachettini, Sara; Carlo, Leonetti; Ortaggi, Giancarlo; Manuela, Porru; Bianco, Armandodoriano; Annamaria, Biroccio | |
| Erratum: Identification of novel RHPS4-derivative ligands with improved toxicological profiles and telomere-targeting activities (Journal of Experimental & Clinical Cancer Research (2014) 33 (81)) | 2015 | Rizzo, Angela; Iachettini, Sara; Zizza, Pasquale; Cingolani, Chiara; Porru, Manuela; Artuso, Simona; Stevens, Malcolm; Hummersone, Marc; Biroccio, Annamaria; Salvati, Erica; Leonetti, Carlo | |
| Evidence for G-quadruplex in the promoter of vegfr-2 and its targeting to inhibit tumor angiogenesis | 2014 | Salvati, E; Zizza, P; Rizzo, A; Iachettini, Sara; Cingolani, Chiara; D'Angelo, C; Porru, M; Randazzo, A; Pagano, B; Novellino, E; Pisanu, Me; Stoppacciaro, Antonella; Spinella, F; Bagnato, A; Gilson, E; Leonetti, C; Biroccio, A. | |
| Identification of novel RHPS4-derivative ligands with improved toxicological profiles and telomere-targeting activities. | 2014 | Rizzo, A; Iachettini, Sara; Zizza, P; Cingolani, Chiara; Porru, M; Artuso, S; Stevens, M; Hummersone, M; Biroccio, A; Salvati, E; Leonetti, C. | |
| Molecular mechanism and biological activity of G-quadruplex ligands, a new potential class of antitumoral agents | 2016 | Iachettini, Sara | |
| N-Cyclic Bay-Substituted Perylene G-Quadruplex Ligands Have Selective Antiproliferative Effects on Cancer Cells and Induce Telomere Damage | 2011 | Casagrande, Valentina; Erica, Salvati; Alvino, Antonello; Bianco, Armandodoriano; Alina, Ciammaichella; C., Dangelo; GINNARI SATRIANI, Luca; Serrilli, ANNA MARIA; Iachettini, Sara; Carlo, Leonetti; Stephen, Neidle; Ortaggi, Giancarlo; Manuela, Porru; Angela, Rizzo; Marco, Franceschin; Annamaria, Biroccio | |
| On and off-target effects of telomere uncapping G-quadruplex selective ligands based on pentacyclic acridinium salts. | 2013 | Iachettini, Sara; Stevens, Mf; Frigerio, M; Hummersone, Mg; Hutchinson, I; Garner, Tp; Searle, Ms; Wilson, Dw; Munde, M; Nanjunda, R; D'Angelo, C; Zizza, P; Rizzo, A; Cingolani, Chiara; De Cicco, F; Porru, M; D'Incalci, M; Leonetti, C; Biroccio, A; Salvati, E. | |
| PARP1 is activated at telomeres upon G4 stabilization: possible target for telomere-based therapy. | 2010 | Salvati, E; Scarsella, M; Porru, M; Rizzo, A; Iachettini, Sara; Tentori, L; Graziani, G; D'Incalci, M; Stevens, Mf; Orlandi, A; Passeri, D; Gilson, E; Zupi, G; Leonetti, C; Biroccio, A. | |
| Perylene and coronene derivatives binding to G-rich promoter oncogene sequences efficiently reduce their expression in cancer cells | 2016 | Micheli, Emanuela; Altieri, Alessandro; Cianni, Lorenzo; Cingolani, Chiara; Iachettini, Sara; Bianco, Armandodoriano; Leonetti, Carlo; Cacchione, Stefano; Biroccio, Annamaria; Franceschin, Marco; Rizzo, Angela | |
| Selective targeting of cancer-related G-quadruplex structures by the natural compound dicentrine | 2023 | Platella, Chiara; Ghirga, Francesca; Musumeci, Domenica; Quaglio, Deborah; Zizza, Pasquale; Iachettini, Sara; D’Angelo, Carmen; Biroccio, Annamaria; Botta, Bruno; Mori, Mattia; Montesarchio, Daniela | |
| Shooting for selective druglike G-quadruplex binders: evidence for telomeric DNA damage and tumor cell death. | 2012 | Cosconati, S; Rizzo, A; Trotta, R; Pagano, B; Iachettini, Sara; De Tito, S; Lauri, I; Fotticchia, I; Giustiniano, M; Marinelli, L; Giancola, C; Novellino, E; Biroccio, A; Randazzo, A. | |
| Tibialis anterior muscle needle biopsy and sensitive biomolecular methods: A useful tool in myotonic dystrophy type 1 | 2015 | Iachettini, Sara; Valaperta, R.; Marchesi, Andrea; Perfetti, A.; Cuomo, G.; Fossati, B.; Vaienti, L.; Costa, E.; Meola, G.; Cardani, Rosanna |