TRAMUTOLA, ANTONELLA
TRAMUTOLA, ANTONELLA
DIPARTIMENTO DI SCIENZE BIOCHIMICHE "ALESSANDRO ROSSI FANELLI"
Aberrant crosstalk between insulin signaling and mTOR in young Down syndrome individuals revealed by neuronal-derived extracellular vesicles
2022 Perluigi, M.; Picca, A.; Montanari, E.; Calvani, R.; Marini, F.; Matassa, R.; Tramutola, A.; Villani, A.; Familiari, G.; Domenico, F. D.; Butterfield, D. A.; Oh, K. J.; Marzetti, E.; Valentini, D.; Barone, E.
Activation of p53 in down syndrome and in the ts65dn mouse brain is associated with a pro-apoptotic phenotype
2016 Tramutola, Antonella; Pupo, Gilda; DI DOMENICO, Fabio; Barone, Eugenio; Arena, Andrea; Lanzillotta, Chiara; Broekaart, Diede; Blarzino, Carla; Head, Elizabeth; Butterfield, D. Allan; Perluigi, Marzia
Age-related changes in the proteostasis network in the brain of the naked mole-rat: Implications promoting healthy longevity.
2015 Triplett, Jc; Tramutola, Antonella; Swomley, A; Kirk, J; Grimes, K; Lewis, K; Orr, M; Rodriguez, K; Cai, J; Klein, Jb; Perluigi, Marzia; Buffenstein, R; Butterfield, D. A.
Aging exacerbates oxidative stress and liver fibrosis in an animal model of Down Syndrome
2024 Giallongo, S.; Ferrigno, J.; Caltabiano, R.; Broggi, G.; Alanazi, A. M.; Distefano, A.; Tropea, E.; Tramutola, A.; Perluigi, M.; Volti, G. L.; Barone, E.; Barbagallo, I. A.
Alteration of mTOR signaling occurs early in the progression of Alzheimer disease (AD): analysis of brain from subjects with pre-clinical AD, amnestic mild cognitive impairment and late-stage AD
2015 Tramutola, Antonella; Triplett, Judy C.; DI DOMENICO, Fabio; Niedowicz, Dana M.; Murphy, Michael P.; Coccia, Raffaella; Perluigi, Marzia; Butterfield, D. Allan
Antiretroviral agents increase NO production in gp120/IFNγ-stimulated cultures of rat microglia via an arginase-dependent mechanism.
2014 Lisi, L; Tramutola, Antonella; Navarra, P; Dello Russo, C.
Biliverdin reductase-A impairment links brain insulin resistance with increased Aβ production in an animal model of aging: implications for Alzheimer disease
2018 Triani, F; Tramutola, A; Di Domenico, F; Sharma, N; Butterfield, Da; Head, E; Perluigi, M; Barone, E
Biliverdin reductase-A integrates insulin signaling with mitochondrial metabolism through phosphorylation of GSK3β
2024 Lanzillotta, Chiara; Tramutola, Antonella; Lanzillotta, Simona; Greco, Viviana; Pagnotta, Sara; Sanchini, Caterina; Di Angelantonio, Silvia; Forte, Elena; Rinaldo, Serena; Paone, Alessio; Cutruzzolà, Francesca; Cimini, Flavia Agata; Barchetta, Ilaria; Cavallo, Maria Gisella; Urbani, Andrea; Butterfield, D Allan; Di Domenico, Fabio; Paul, Bindu D; Perluigi, Marzia; Duarte, Joao M N; Barone, Eugenio
Biliverdin reductase-A mediates the beneficial effects of intranasal insulin in Alzheimer disease
2019 Barone, E; Tramutola, A; Triani, F; Calcagnini, S; Di Domenico, F; Ripoli, C; Gaetani, S; Grassi, C; Butterfield, Da; Cassano, T; Perluigi, M
Brain insulin resistance triggers early onset Alzheimer disease in Down syndrome
2020 Tramutola, A.; Lanzillotta, C.; Di Domenico, F.; Head, E.; Butterfield, D. A.; Perluigi, M.; Barone, E.
CAPE and its synthetic derivative VP961 restore BACH1/NRF2 axis in Down syndrome
2022 Pagnotta, S.; Tramutola, A.; Barone, E.; Di Domenico, F.; Pittala, V.; Salerno, L.; Folgiero, V.; Caforio, M.; Locatelli, F.; Petrini, S.; Butterfield, D. A.; Perluigi, M.
Cathepsin D as a therapeutic target in Alzheimer’s disease
2016 DI DOMENICO, Fabio; Tramutola, Antonella; Perluigi, Marzia
Chronic perk induction promotes alzheimer-like neuropathology in down syndrome: Insights for therapeutic intervention
2021 Lanzillotta, C.; Zuliani, I.; Tramutola, A.; Barone, E.; Blarzino, C.; Folgiero, V.; Caforio, M.; Valentini, D.; Villani, A.; Locatelli, F.; Butterfield, D. A.; Head, E.; Perluigi, M.; Abisambra, J. F.; Di Domenico, F.
Circulating dipeptidyl peptidase-4 is independently associated with the presence and severity of NAFLD/NASH in individuals with and without obesity and metabolic disease
2021 Barchetta, I.; Ceccarelli, V.; Cimini, F. A.; Barone, E.; Sentinelli, F.; Coluzzi, M.; Chiappetta, C.; Bertoccini, L.; Tramutola, A.; Labbadia, G.; Di Cristofano, C.; Silecchia, G.; Leonetti, F.; Cavallo, M. G.
Cytosolic serine hydroxymethyltransferase controls lung adenocarcinoma cells migratory ability by modulating AMP kinase activity
2020 Bouzidi, Amani; Magnifico, Maria Chiara; Paiardini, Alessandro; Macone, Alberto; Boumis, Giovanna; Giardina, Giorgio; Rinaldo, Serena; Liberati, Francesca Romana; Lauro, Clotilde; Limatola, Cristina; Lanzillotta, Chiara; Tramutola, Antonella; Perluigi, Marzia; Sgarbi, Gianluca; Solaini, Giancarlo; Baracca, Alessandra; Paone, Alessio; Cutruzzolà, Francesca
Dynamic changes of BVRA protein levels occur in response to insulin: a pilot study in humans
2023 Cimini, Flavia Agata; Tramutola, Antonella; Barchetta, Ilaria; Ceccarelli, Valentina; Gangitano, Elena; Lanzillotta, Simona; Lanzillotta, Chiara; Cavallo, Maria Gisella; Barone, Eugenio
Early and selective activation and subsequent alterations to the unfolded protein response in down syndrome mouse models
2018 Lanzillotta, Chiara; Tramutola, Antonella; Meier, Shelby; Schmitt, Frederick; Barone, Eugenio; Perluigi, Marzia; Di Domenico, Fabio; Abisambra, Jose F
Engineering memory with an extrinsically disordered kinase
2023 Ripoli, Cristian; Dagliyan, Onur; Renna, Pietro; Pastore, Francesco; Paciello, Fabiola; Sollazzo, Raimondo; Rinaudo, Marco; Battistoni, Martina; Martini, Sara; Tramutola, Antonella; Sattin, Andrea; Barone, Eugenio; Saneyoshi, Takeo; Fellin, Tommaso; Hayashi, Yasunori; Grassi, Claudio
GLUT-1 changes in paediatric Huntington disease brain cortex and fibroblasts: an observational case-control study
2023 Tramutola, Antonella; S Bakels, Hannah; Perrone, Federica; Di Nottia, Michela; Mazza, Tommaso; Abruzzese, MARIA PIA; Zoccola, Martina; Pagnotta, Sara; Carrozzo, Rosalba; T de Bot, Susanne; Perluigi, Marzia; C van Roon-Mom, Willeke M; Squitieri, Ferdinando
Greater circulating DPP4 activity is associated with impaired flow-mediated dilatation in adults with type 2 diabetes mellitus
2019 Barchetta, I.; Ciccarelli, G.; Barone, E.; Cimini, F. A.; Ceccarelli, V.; Bertoccini, L.; Sentinelli, F.; Tramutola, A.; Del Ben, M.; Angelico, F.; Baroni, M. G.; Lenzi, A.; Cavallo, M. G.
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| Aberrant crosstalk between insulin signaling and mTOR in young Down syndrome individuals revealed by neuronal-derived extracellular vesicles | 2022 | Perluigi, M.; Picca, A.; Montanari, E.; Calvani, R.; Marini, F.; Matassa, R.; Tramutola, A.; Villani, A.; Familiari, G.; Domenico, F. D.; Butterfield, D. A.; Oh, K. J.; Marzetti, E.; Valentini, D.; Barone, E. | |
| Activation of p53 in down syndrome and in the ts65dn mouse brain is associated with a pro-apoptotic phenotype | 2016 | Tramutola, Antonella; Pupo, Gilda; DI DOMENICO, Fabio; Barone, Eugenio; Arena, Andrea; Lanzillotta, Chiara; Broekaart, Diede; Blarzino, Carla; Head, Elizabeth; Butterfield, D. Allan; Perluigi, Marzia | |
| Age-related changes in the proteostasis network in the brain of the naked mole-rat: Implications promoting healthy longevity. | 2015 | Triplett, Jc; Tramutola, Antonella; Swomley, A; Kirk, J; Grimes, K; Lewis, K; Orr, M; Rodriguez, K; Cai, J; Klein, Jb; Perluigi, Marzia; Buffenstein, R; Butterfield, D. A. | |
| Aging exacerbates oxidative stress and liver fibrosis in an animal model of Down Syndrome | 2024 | Giallongo, S.; Ferrigno, J.; Caltabiano, R.; Broggi, G.; Alanazi, A. M.; Distefano, A.; Tropea, E.; Tramutola, A.; Perluigi, M.; Volti, G. L.; Barone, E.; Barbagallo, I. A. | |
| Alteration of mTOR signaling occurs early in the progression of Alzheimer disease (AD): analysis of brain from subjects with pre-clinical AD, amnestic mild cognitive impairment and late-stage AD | 2015 | Tramutola, Antonella; Triplett, Judy C.; DI DOMENICO, Fabio; Niedowicz, Dana M.; Murphy, Michael P.; Coccia, Raffaella; Perluigi, Marzia; Butterfield, D. Allan | |
| Antiretroviral agents increase NO production in gp120/IFNγ-stimulated cultures of rat microglia via an arginase-dependent mechanism. | 2014 | Lisi, L; Tramutola, Antonella; Navarra, P; Dello Russo, C. | |
| Biliverdin reductase-A impairment links brain insulin resistance with increased Aβ production in an animal model of aging: implications for Alzheimer disease | 2018 | Triani, F; Tramutola, A; Di Domenico, F; Sharma, N; Butterfield, Da; Head, E; Perluigi, M; Barone, E | |
| Biliverdin reductase-A integrates insulin signaling with mitochondrial metabolism through phosphorylation of GSK3β | 2024 | Lanzillotta, Chiara; Tramutola, Antonella; Lanzillotta, Simona; Greco, Viviana; Pagnotta, Sara; Sanchini, Caterina; Di Angelantonio, Silvia; Forte, Elena; Rinaldo, Serena; Paone, Alessio; Cutruzzolà, Francesca; Cimini, Flavia Agata; Barchetta, Ilaria; Cavallo, Maria Gisella; Urbani, Andrea; Butterfield, D Allan; Di Domenico, Fabio; Paul, Bindu D; Perluigi, Marzia; Duarte, Joao M N; Barone, Eugenio | |
| Biliverdin reductase-A mediates the beneficial effects of intranasal insulin in Alzheimer disease | 2019 | Barone, E; Tramutola, A; Triani, F; Calcagnini, S; Di Domenico, F; Ripoli, C; Gaetani, S; Grassi, C; Butterfield, Da; Cassano, T; Perluigi, M | |
| Brain insulin resistance triggers early onset Alzheimer disease in Down syndrome | 2020 | Tramutola, A.; Lanzillotta, C.; Di Domenico, F.; Head, E.; Butterfield, D. A.; Perluigi, M.; Barone, E. | |
| CAPE and its synthetic derivative VP961 restore BACH1/NRF2 axis in Down syndrome | 2022 | Pagnotta, S.; Tramutola, A.; Barone, E.; Di Domenico, F.; Pittala, V.; Salerno, L.; Folgiero, V.; Caforio, M.; Locatelli, F.; Petrini, S.; Butterfield, D. A.; Perluigi, M. | |
| Cathepsin D as a therapeutic target in Alzheimer’s disease | 2016 | DI DOMENICO, Fabio; Tramutola, Antonella; Perluigi, Marzia | |
| Chronic perk induction promotes alzheimer-like neuropathology in down syndrome: Insights for therapeutic intervention | 2021 | Lanzillotta, C.; Zuliani, I.; Tramutola, A.; Barone, E.; Blarzino, C.; Folgiero, V.; Caforio, M.; Valentini, D.; Villani, A.; Locatelli, F.; Butterfield, D. A.; Head, E.; Perluigi, M.; Abisambra, J. F.; Di Domenico, F. | |
| Circulating dipeptidyl peptidase-4 is independently associated with the presence and severity of NAFLD/NASH in individuals with and without obesity and metabolic disease | 2021 | Barchetta, I.; Ceccarelli, V.; Cimini, F. A.; Barone, E.; Sentinelli, F.; Coluzzi, M.; Chiappetta, C.; Bertoccini, L.; Tramutola, A.; Labbadia, G.; Di Cristofano, C.; Silecchia, G.; Leonetti, F.; Cavallo, M. G. | |
| Cytosolic serine hydroxymethyltransferase controls lung adenocarcinoma cells migratory ability by modulating AMP kinase activity | 2020 | Bouzidi, Amani; Magnifico, Maria Chiara; Paiardini, Alessandro; Macone, Alberto; Boumis, Giovanna; Giardina, Giorgio; Rinaldo, Serena; Liberati, Francesca Romana; Lauro, Clotilde; Limatola, Cristina; Lanzillotta, Chiara; Tramutola, Antonella; Perluigi, Marzia; Sgarbi, Gianluca; Solaini, Giancarlo; Baracca, Alessandra; Paone, Alessio; Cutruzzolà, Francesca | |
| Dynamic changes of BVRA protein levels occur in response to insulin: a pilot study in humans | 2023 | Cimini, Flavia Agata; Tramutola, Antonella; Barchetta, Ilaria; Ceccarelli, Valentina; Gangitano, Elena; Lanzillotta, Simona; Lanzillotta, Chiara; Cavallo, Maria Gisella; Barone, Eugenio | |
| Early and selective activation and subsequent alterations to the unfolded protein response in down syndrome mouse models | 2018 | Lanzillotta, Chiara; Tramutola, Antonella; Meier, Shelby; Schmitt, Frederick; Barone, Eugenio; Perluigi, Marzia; Di Domenico, Fabio; Abisambra, Jose F | |
| Engineering memory with an extrinsically disordered kinase | 2023 | Ripoli, Cristian; Dagliyan, Onur; Renna, Pietro; Pastore, Francesco; Paciello, Fabiola; Sollazzo, Raimondo; Rinaudo, Marco; Battistoni, Martina; Martini, Sara; Tramutola, Antonella; Sattin, Andrea; Barone, Eugenio; Saneyoshi, Takeo; Fellin, Tommaso; Hayashi, Yasunori; Grassi, Claudio | |
| GLUT-1 changes in paediatric Huntington disease brain cortex and fibroblasts: an observational case-control study | 2023 | Tramutola, Antonella; S Bakels, Hannah; Perrone, Federica; Di Nottia, Michela; Mazza, Tommaso; Abruzzese, MARIA PIA; Zoccola, Martina; Pagnotta, Sara; Carrozzo, Rosalba; T de Bot, Susanne; Perluigi, Marzia; C van Roon-Mom, Willeke M; Squitieri, Ferdinando | |
| Greater circulating DPP4 activity is associated with impaired flow-mediated dilatation in adults with type 2 diabetes mellitus | 2019 | Barchetta, I.; Ciccarelli, G.; Barone, E.; Cimini, F. A.; Ceccarelli, V.; Bertoccini, L.; Sentinelli, F.; Tramutola, A.; Del Ben, M.; Angelico, F.; Baroni, M. G.; Lenzi, A.; Cavallo, M. G. |