MANCINI, ANDREA
MANCINI, ANDREA
DIPARTIMENTO DI CHIMICA E TECNOLOGIE DEL FARMACO
Deubiquitinase-targeting chimeras (DUBTACs). A game-changing approach for targeted protein stabilization in drug discovery
2026 Hailu, Gebremedhin Solomon; Fabbrizi, Emanuele; Mancini, Andrea; Fiorentino, Francesco; Mai, Antonello; Rotili, Dante
Exploring the role of conformational restriction in 5-alkyl-6-benzyl-2-{[(methylthio)methyl]thio}pyrimidin-4(3H)-ones. Effects in HIV-1 infected cells and reverse transcriptase enzymes
2026 Degtyarenko, Egor; Hailu, Gebremedhin Solomon; Fabbrizi, Emanuele; Golovina, Anastasia; Voronkov, Andrey; Astolfi, Roberta; Giuliani, Lidia; Mancini, Andrea; Nawrozkij, Maxim B; Chernyshov, Vladimir; Pupillo, Clarissa; Cirilli, Roberto; Bavagnoli, Laura; Ragno, Rino; Esté, José A; Crespan, Emmanuele; Fiorentino, Francesco; Ivanov, Roman; Mai, Antonello; Rotili, Dante
METTL1/WDR4 Complex: A Novel Epitranscriptomic Target at the Crossroads of RNA Methylation and Drug Discovery
2026 Fabbrizi, Emanuele; Hailu, Gebremedhin Solomon; Mancini, Andrea; Mai, Antonello; Fiorentino, Francesco; Rotili, Dante
Molecular striptease of a thiadiazolopyrimidine hit yields a streamlined, artifact-free NADPH mimic for NOX inhibition
2026 Fabbrizi, Emanuele; Mancini, Andrea; Lambona, Chiara; Macrì, Salvatore; Nalli, Marianna; Quilli, Francesco; Pandolfi, Federico; Raimondo, Domenico; Marchese, Sara; Mattevi, Andrea; Lee, Jihyeon; Choi, Minhye; Soo Bae, Yun; Hristova-Avakumova, Nadya; Kondeva-Burdina, Magdalena; Stefanova, Denitsa; Anastassova, Neda; Valente, Sergio; Rotili, Dante; Mai, Antonello
Systematic structure–activity relationship investigation on novel 5-alkyl-6-benzyl-2-{[(methylthio/phenylthio)alkyl]thio}-pyrimidin-4(3H)-ones endowed with potent anti-hiv-1 activity
2026 Hailu, Gebremedhin Solomon; Degtyarenko, Egor; Fabbrizi, Emanuele; Golovina, Anastasia; Voronkov, Andrey; Mancini, Andrea; Nawrozkij, Maxim B.; Chernyshov, Vladimir; Bavagnoli, Laura; Bianchi, Elena; Astolfi, Roberta; Ragno, Rino; Esté, José A.; Crespan, Emmanuele; Fiorentino, Francesco; Ivanov, Roman; Mai, Antonello; Rotili, Dante
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| Deubiquitinase-targeting chimeras (DUBTACs). A game-changing approach for targeted protein stabilization in drug discovery | 2026 | Hailu, Gebremedhin Solomon; Fabbrizi, Emanuele; Mancini, Andrea; Fiorentino, Francesco; Mai, Antonello; Rotili, Dante | |
| Exploring the role of conformational restriction in 5-alkyl-6-benzyl-2-{[(methylthio)methyl]thio}pyrimidin-4(3H)-ones. Effects in HIV-1 infected cells and reverse transcriptase enzymes | 2026 | Degtyarenko, Egor; Hailu, Gebremedhin Solomon; Fabbrizi, Emanuele; Golovina, Anastasia; Voronkov, Andrey; Astolfi, Roberta; Giuliani, Lidia; Mancini, Andrea; Nawrozkij, Maxim B; Chernyshov, Vladimir; Pupillo, Clarissa; Cirilli, Roberto; Bavagnoli, Laura; Ragno, Rino; Esté, José A; Crespan, Emmanuele; Fiorentino, Francesco; Ivanov, Roman; Mai, Antonello; Rotili, Dante | |
| METTL1/WDR4 Complex: A Novel Epitranscriptomic Target at the Crossroads of RNA Methylation and Drug Discovery | 2026 | Fabbrizi, Emanuele; Hailu, Gebremedhin Solomon; Mancini, Andrea; Mai, Antonello; Fiorentino, Francesco; Rotili, Dante | |
| Molecular striptease of a thiadiazolopyrimidine hit yields a streamlined, artifact-free NADPH mimic for NOX inhibition | 2026 | Fabbrizi, Emanuele; Mancini, Andrea; Lambona, Chiara; Macrì, Salvatore; Nalli, Marianna; Quilli, Francesco; Pandolfi, Federico; Raimondo, Domenico; Marchese, Sara; Mattevi, Andrea; Lee, Jihyeon; Choi, Minhye; Soo Bae, Yun; Hristova-Avakumova, Nadya; Kondeva-Burdina, Magdalena; Stefanova, Denitsa; Anastassova, Neda; Valente, Sergio; Rotili, Dante; Mai, Antonello | |
| Systematic structure–activity relationship investigation on novel 5-alkyl-6-benzyl-2-{[(methylthio/phenylthio)alkyl]thio}-pyrimidin-4(3H)-ones endowed with potent anti-hiv-1 activity | 2026 | Hailu, Gebremedhin Solomon; Degtyarenko, Egor; Fabbrizi, Emanuele; Golovina, Anastasia; Voronkov, Andrey; Mancini, Andrea; Nawrozkij, Maxim B.; Chernyshov, Vladimir; Bavagnoli, Laura; Bianchi, Elena; Astolfi, Roberta; Ragno, Rino; Esté, José A.; Crespan, Emmanuele; Fiorentino, Francesco; Ivanov, Roman; Mai, Antonello; Rotili, Dante |