MARROCCO, BIAGINA
MARROCCO, BIAGINA
DIPARTIMENTO DI MEDICINA MOLECOLARE
Design and Synthesis of Simplified Largazole Analogues as Isoform-Selective Human Lysine Deacetylase Inhibitors
2016 Reddy, Damodara N; Ballante, Flavio; Chuang, Timothy; Pirolli, Adele; Marrocco, Biagina; Marshall, Garland R.
Development of alkyl glycerone phosphate synthase inhibitors: Structure-activity relationship and effects on ether lipids and epithelial-mesenchymal transition in cancer cells
2019 Stazi, Giulia; Battistelli, Cecilia; Piano, Valentina; Mazzone, Roberta; Marrocco, Biagina; Marchese, Sara; Louie, Sharon M.; Zwergel, Clemens; Antonini, Lorenzo; Patsilinakos, Alexandros; Ragno, Rino; Viviano, Monica; Sbardella, Gianluca; Ciogli, Alessia; Fabrizi, Giancarlo; Cirilli, Roberto; Strippoli, Raffaele; Marchetti, Alessandra; Tripodi, Marco; Nomura, Daniel K.; Mattevi, Andrea; Mai, Antonello; Valente, Sergio
Discovery of a novel inhibitor of histone lysine-specific demethylase 1A (KDM1A/LSD1) as orally active antitumor agent
2016 Vianello, Paola; Botrugno, Oronza A; Cappa, Anna; Dal Zuffo, Roberto; Dessanti, Paola; Mai, Antonello; Marrocco, Biagina; Mattevi, Andrea; Meroni, Giuseppe; Minucci, Saverio; Stazi, Giulia; Thaler, Florian; Trifiró, Paolo; Valente, Sergio; Villa, Manuela; Varasi, Mario; Mercurio, Ciro
Discovery of inhibitors for the ether lipid-generating enzyme AGPS as anti-cancer agents
2015 Piano, Valentina; Benjamin, Daniel I.; Valente, Sergio; Nenci, Simone; Marrocco, Biagina; Mai, Antonello; Aliverti, Alessandro; Nomura, Daniel K; Mattevi, Andrea
Exploring the role of 2-chloro-6-fluoro substitution in 2-alkylthio-6-benzyl-5-alkylpyrimidin-4(3H)-ones: effects in HIV-1-infected cells and in HIV-1 reverse transcriptase enzymes
2014 Rotili, Dante; Tarantino, D; Nawrozkij, Mb; Babushkin, As; Botta, G; Marrocco, Biagina; Cirilli, R; Menta, Sergio; Badia, R; Crespan, E; Ballante, Flavio; Ragno, Rino; Esté, Ja; Maga, G; Mai, Antonello
Histone deacetylase inhibitors restore IL-10 expression in lipopolysaccharide-induced cell inflammation and reduce IL-1β and IL-6 production in breast silicone implant in C57BL/6J wild-type murine model
2016 Di Liddo, Rosa; Valente, Sergio; Taurone, Samanta; Zwergel, Clemens; Marrocco, Biagina; Turchetta, Rosaria; Conconi, Maria Teresa; Scarpa, Carlotta; Bertalot, Thomas; Schrenk, Sandra; Mai, Antonello; Artico, Marco
Novel non-covalent LSD1 inhibitors endowed with anticancer effects in leukemia and solid tumor cellular models
2022 Menna, M.; Fiorentino, F.; Marrocco, B.; Lucidi, A.; Tomassi, S.; Cilli, D.; Romanenghi, M.; Cassandri, M.; Pomella, S.; Pezzella, M.; Del Bufalo, D.; Zeya Ansari, M. S.; Tomasevic, N.; Mladenovic, M.; Viviano, M.; Sbardella, G.; Rota, R.; Trisciuoglio, D.; Minucci, S.; Mattevi, A.; Rotili, D.; Mai, A.
Pan-histone demethylase inhibitors simultaneously targeting Jumonji C and lysine-specific demethylases display high anticancer activities
2014 Rotili, Dante; Stefano, Tomassi; Mariarosaria, Conte; Rosaria, Benedetti; Marcello, Tortorici; Giuseppe, Ciossani; Valente, Sergio; Marrocco, Biagina; Labella, Donatella; Ettore, Novellino; Andrea, Mattevi; Lucia, Altucci; Tumber, Anthony; Yapp, Clarence; N. F., King Oliver; Richard J., Hopkinson; Akane, Kawamura; J., Schofield Christopher; Mai, Antonello
Properly substituted analogues of BIX-01294 lose inhibition of G9a histone methyltransferase and gain selective anti-DNA methyltransferase 3A activity.
2014 Rotili, Dante; Tarantino, D; Marrocco, Biagina; Gros, C; Masson, V; Poughon, V; Ausseil, F; Chang, Y; Labella, D; Cosconati, S; Di Maro, S; Novellino, E; Schnekenburger, M; Grandjenette, C; Bouvy, C; Diederich, M; Cheng, X; Arimondo, Pb; Mai, Antonello
Pure diastereomers of a tranylcypromine-based LSD1 inhibitor: enzyme selectivity and in-cell studies
2015 VALENTE, Sergio; Veronica, Rodriguez; Ciro, Mercurio; Paola, Vianello; Bruna, Saponara; Roberto, Cirilli; Giuseppe, Ciossani; LABELLA, DONATELLA; MARROCCO, BIAGINA; RUOPPOLO, Giovanni; Oronza A., Botrugno; Paola, Dessanti; Saverio, Minucci; Andrea, Mattevi; Mario, Varasi; MAI, Antonello
Pure enantiomers of benzoylamino-tranylcypromine: LSD1 inhibition, gene modulation in human leukemia cells and effects on clonogenic potential of murine promyelocytic blasts
2015 Valente, Sergio; Veronica, Rodriguez; Mercurio, Ciro; Vianello, Paola; Saponara, Bruna; Cirilli, Roberto; Ciossani, Giuseppe; Labella, Donatella; Marrocco, Biagina; Monaldi, Daria; Ruoppolo, Giovanni; Tilset, Mats; Botrugno, Oronza A.; Dessanti, Paola; Minucci, Saverio; Mattevi, Andrea; Varasi, Mario; Mai, Antonello
Pyrazole-based inhibitors of enhancer of zeste homologue 2 induce apoptosis and autophagy in cancer cells
2018 Mellini, Paolo; Marrocco, Biagina; Borovika, Diana; Polletta, Lucia; Carnevale, Ilaria; Saladini, Serena; Stazi, Giulia; Zwergel, Clemens; Trapencieris, Peteris; Ferretti, Elisabetta; Tafani, Marco; Valente, Sergio; Mai, Antonello
The histone methyltransferase EZH2 as a druggable target in SHH medulloblastoma cancer stem cells
2017 Miele, Evelina; Valente, Sergio; Alfano, Vincenzo; Silvano, Marianna; Mellini, Paolo; Borovika, Diana; Marrocco, Biagina; Po, Agnese; Besharat, Zein Mersini; Catanzaro, Giuseppina; Battaglia, Giuseppe; Abballe, Luana; Zwergel, Clemens; Stazi, Giulia; Milite, Ciro; Castellano, Sabrina; Tafani, Marco; Trapencieris, Peteris; Mai, Antonello; Ferretti, Elisabetta
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| Design and Synthesis of Simplified Largazole Analogues as Isoform-Selective Human Lysine Deacetylase Inhibitors | 2016 | Reddy, Damodara N; Ballante, Flavio; Chuang, Timothy; Pirolli, Adele; Marrocco, Biagina; Marshall, Garland R. | |
| Development of alkyl glycerone phosphate synthase inhibitors: Structure-activity relationship and effects on ether lipids and epithelial-mesenchymal transition in cancer cells | 2019 | Stazi, Giulia; Battistelli, Cecilia; Piano, Valentina; Mazzone, Roberta; Marrocco, Biagina; Marchese, Sara; Louie, Sharon M.; Zwergel, Clemens; Antonini, Lorenzo; Patsilinakos, Alexandros; Ragno, Rino; Viviano, Monica; Sbardella, Gianluca; Ciogli, Alessia; Fabrizi, Giancarlo; Cirilli, Roberto; Strippoli, Raffaele; Marchetti, Alessandra; Tripodi, Marco; Nomura, Daniel K.; Mattevi, Andrea; Mai, Antonello; Valente, Sergio | |
| Discovery of a novel inhibitor of histone lysine-specific demethylase 1A (KDM1A/LSD1) as orally active antitumor agent | 2016 | Vianello, Paola; Botrugno, Oronza A; Cappa, Anna; Dal Zuffo, Roberto; Dessanti, Paola; Mai, Antonello; Marrocco, Biagina; Mattevi, Andrea; Meroni, Giuseppe; Minucci, Saverio; Stazi, Giulia; Thaler, Florian; Trifiró, Paolo; Valente, Sergio; Villa, Manuela; Varasi, Mario; Mercurio, Ciro | |
| Discovery of inhibitors for the ether lipid-generating enzyme AGPS as anti-cancer agents | 2015 | Piano, Valentina; Benjamin, Daniel I.; Valente, Sergio; Nenci, Simone; Marrocco, Biagina; Mai, Antonello; Aliverti, Alessandro; Nomura, Daniel K; Mattevi, Andrea | |
| Exploring the role of 2-chloro-6-fluoro substitution in 2-alkylthio-6-benzyl-5-alkylpyrimidin-4(3H)-ones: effects in HIV-1-infected cells and in HIV-1 reverse transcriptase enzymes | 2014 | Rotili, Dante; Tarantino, D; Nawrozkij, Mb; Babushkin, As; Botta, G; Marrocco, Biagina; Cirilli, R; Menta, Sergio; Badia, R; Crespan, E; Ballante, Flavio; Ragno, Rino; Esté, Ja; Maga, G; Mai, Antonello | |
| Histone deacetylase inhibitors restore IL-10 expression in lipopolysaccharide-induced cell inflammation and reduce IL-1β and IL-6 production in breast silicone implant in C57BL/6J wild-type murine model | 2016 | Di Liddo, Rosa; Valente, Sergio; Taurone, Samanta; Zwergel, Clemens; Marrocco, Biagina; Turchetta, Rosaria; Conconi, Maria Teresa; Scarpa, Carlotta; Bertalot, Thomas; Schrenk, Sandra; Mai, Antonello; Artico, Marco | |
| Novel non-covalent LSD1 inhibitors endowed with anticancer effects in leukemia and solid tumor cellular models | 2022 | Menna, M.; Fiorentino, F.; Marrocco, B.; Lucidi, A.; Tomassi, S.; Cilli, D.; Romanenghi, M.; Cassandri, M.; Pomella, S.; Pezzella, M.; Del Bufalo, D.; Zeya Ansari, M. S.; Tomasevic, N.; Mladenovic, M.; Viviano, M.; Sbardella, G.; Rota, R.; Trisciuoglio, D.; Minucci, S.; Mattevi, A.; Rotili, D.; Mai, A. | |
| Pan-histone demethylase inhibitors simultaneously targeting Jumonji C and lysine-specific demethylases display high anticancer activities | 2014 | Rotili, Dante; Stefano, Tomassi; Mariarosaria, Conte; Rosaria, Benedetti; Marcello, Tortorici; Giuseppe, Ciossani; Valente, Sergio; Marrocco, Biagina; Labella, Donatella; Ettore, Novellino; Andrea, Mattevi; Lucia, Altucci; Tumber, Anthony; Yapp, Clarence; N. F., King Oliver; Richard J., Hopkinson; Akane, Kawamura; J., Schofield Christopher; Mai, Antonello | |
| Properly substituted analogues of BIX-01294 lose inhibition of G9a histone methyltransferase and gain selective anti-DNA methyltransferase 3A activity. | 2014 | Rotili, Dante; Tarantino, D; Marrocco, Biagina; Gros, C; Masson, V; Poughon, V; Ausseil, F; Chang, Y; Labella, D; Cosconati, S; Di Maro, S; Novellino, E; Schnekenburger, M; Grandjenette, C; Bouvy, C; Diederich, M; Cheng, X; Arimondo, Pb; Mai, Antonello | |
| Pure diastereomers of a tranylcypromine-based LSD1 inhibitor: enzyme selectivity and in-cell studies | 2015 | VALENTE, Sergio; Veronica, Rodriguez; Ciro, Mercurio; Paola, Vianello; Bruna, Saponara; Roberto, Cirilli; Giuseppe, Ciossani; LABELLA, DONATELLA; MARROCCO, BIAGINA; RUOPPOLO, Giovanni; Oronza A., Botrugno; Paola, Dessanti; Saverio, Minucci; Andrea, Mattevi; Mario, Varasi; MAI, Antonello | |
| Pure enantiomers of benzoylamino-tranylcypromine: LSD1 inhibition, gene modulation in human leukemia cells and effects on clonogenic potential of murine promyelocytic blasts | 2015 | Valente, Sergio; Veronica, Rodriguez; Mercurio, Ciro; Vianello, Paola; Saponara, Bruna; Cirilli, Roberto; Ciossani, Giuseppe; Labella, Donatella; Marrocco, Biagina; Monaldi, Daria; Ruoppolo, Giovanni; Tilset, Mats; Botrugno, Oronza A.; Dessanti, Paola; Minucci, Saverio; Mattevi, Andrea; Varasi, Mario; Mai, Antonello | |
| Pyrazole-based inhibitors of enhancer of zeste homologue 2 induce apoptosis and autophagy in cancer cells | 2018 | Mellini, Paolo; Marrocco, Biagina; Borovika, Diana; Polletta, Lucia; Carnevale, Ilaria; Saladini, Serena; Stazi, Giulia; Zwergel, Clemens; Trapencieris, Peteris; Ferretti, Elisabetta; Tafani, Marco; Valente, Sergio; Mai, Antonello | |
| The histone methyltransferase EZH2 as a druggable target in SHH medulloblastoma cancer stem cells | 2017 | Miele, Evelina; Valente, Sergio; Alfano, Vincenzo; Silvano, Marianna; Mellini, Paolo; Borovika, Diana; Marrocco, Biagina; Po, Agnese; Besharat, Zein Mersini; Catanzaro, Giuseppina; Battaglia, Giuseppe; Abballe, Luana; Zwergel, Clemens; Stazi, Giulia; Milite, Ciro; Castellano, Sabrina; Tafani, Marco; Trapencieris, Peteris; Mai, Antonello; Ferretti, Elisabetta |