FIASCARELLI, ALESSIO
FIASCARELLI, ALESSIO
DIPARTIMENTO DI SCIENZE BIOCHIMICHE "ALESSANDRO ROSSI FANELLI"
A pyrazolopyran derivative preferentially inhibits the activity of human cytosolic hydroxymethyltransferase and induces cell death in lung cancer cells
2016 Marani, Marina; Paone, Alessio; Fiascarelli, Alessio; Macone, Alberto; Gargano, Maurizio; Rinaldo, Serena; Giardina, Giorgio; Pontecorvi, Valentino; Koes, David; Mcdermott, Lee; Yang, Tianyi; Paiardini, Alessandro; Contestabile, Roberto; Cutruzzola, Francesca
Antitumor activity of the PI3K δ-sparing inhibitor MEN1611 in PIK3CA mutated, trastuzumab-resistant HER2 + breast cancer
2023 Fiascarelli, Alessio; Merlino, Giuseppe; Capano, Stefania; Talucci, Simone; Bisignano, Diego; Bressan, Alessandro; Bellarosa, Daniela; Carrisi, Corrado; Paoli, Alessandro; Bigioni, Mario; Tunici, Patrizia; Irrissuto, Clelia; Salerno, Massimiliano; Arribas, Joaquin; de Stanchina, Elisa; Scaltriti, Maurizio; Binaschi, Monica
Differential 3-bromopyruvate inhibition of cytosolic and mitochondrial human serine hydroxymethyltransferase isoforms, key enzymes in cancer metabolic reprogramming
2016 Paiardini, Alessandro; Tramonti, Angela; Schirch, Doug; Guiducci, Giulia; DI SALVO, Martino Luigi; Fiascarelli, Alessio; Giorgi, Alessandra; Maras, Bruno; Cutruzzola', Francesca; Contestabile, Roberto
How pyridoxal 5'-phosphate differentially regulates human cytosolic and mitochondrial serine hydroxymethyltransferase oligomeric state
2015 Giardina, Giorgio; Brunotti, Paolo; Fiascarelli, Alessio; Cicalini, A; Costa, Mg; Buckle, Am; DI SALVO, Martino Luigi; Giorgi, Alessandra; Marani, Marina; Paone, Alessio; Rinaldo, Serena; Paiardini, Alessandro; Contestabile, Roberto; Cutruzzola', Francesca
MEN1309/OBT076, a first-in-class antibody–drug conjugate targeting CD205 in solid tumors
2019 Merlino, G.; Fiascarelli, A.; Bigioni, M.; Bressan, A.; Carrisi, C.; Bellarosa, D.; Salerno, M.; Bugianesi, R.; Manno, R.; Morales, C. B.; Arribas, J.; Dusek, R. L.; Ackroyd, J. E.; Pham, P. H.; Awdew, R.; Aud, D.; Trang, M.; Lynch, C. M.; Terrett, J.; Wilson, K. E.; Rohlff, C.; Manzini, S.; Pellacani, A.; Binaschi, M.
Molecular mechanism of pdxr - a transcriptional activator involved in the regulation of vitamin b biosynthesis in the probiotic bacterium Bacillus clausii
2015 Tramonti, Angela; Fiascarelli, Alessio; Milano, Teresa; DI SALVO, Martino Luigi; Nogués, Isabel; Pascarella, Stefano; Contestabile, Roberto
Screening and in vitro testing of antifolate inhibitors of human cytosolic serine hydroxymethyltransferase
2015 Paiardini, Alessandro; Fiascarelli, Alessio; Rinaldo, Serena; Daidone, Frederick; Giardina, Giorgio; Koes, Dr; Parroni, Alessia; Montini, G; Marani, Marina; Paone, Alessio; Mcdermott, La; Contestabile, Roberto; Cutruzzola', Francesca
Serine, Glycine, One-carbon (SGOC) Metabolism and Cancer: Characterization and Inhibition of Serine Hydroxymethyltransferase
2015 Fiascarelli, Alessio
SHMT1 knockdown induces apoptosis in lung cancer cells by causing uracil misincorporation
2014 Paone, Alessio; Marani, Marina; Fiascarelli, Alessio; Rinaldo, Serena; Giardina, Giorgio; Contestabile, Roberto; Paiardini, Alessandro; Cutruzzola', Francesca
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| A pyrazolopyran derivative preferentially inhibits the activity of human cytosolic hydroxymethyltransferase and induces cell death in lung cancer cells | 2016 | Marani, Marina; Paone, Alessio; Fiascarelli, Alessio; Macone, Alberto; Gargano, Maurizio; Rinaldo, Serena; Giardina, Giorgio; Pontecorvi, Valentino; Koes, David; Mcdermott, Lee; Yang, Tianyi; Paiardini, Alessandro; Contestabile, Roberto; Cutruzzola, Francesca | |
| Antitumor activity of the PI3K δ-sparing inhibitor MEN1611 in PIK3CA mutated, trastuzumab-resistant HER2 + breast cancer | 2023 | Fiascarelli, Alessio; Merlino, Giuseppe; Capano, Stefania; Talucci, Simone; Bisignano, Diego; Bressan, Alessandro; Bellarosa, Daniela; Carrisi, Corrado; Paoli, Alessandro; Bigioni, Mario; Tunici, Patrizia; Irrissuto, Clelia; Salerno, Massimiliano; Arribas, Joaquin; de Stanchina, Elisa; Scaltriti, Maurizio; Binaschi, Monica | |
| Differential 3-bromopyruvate inhibition of cytosolic and mitochondrial human serine hydroxymethyltransferase isoforms, key enzymes in cancer metabolic reprogramming | 2016 | Paiardini, Alessandro; Tramonti, Angela; Schirch, Doug; Guiducci, Giulia; DI SALVO, Martino Luigi; Fiascarelli, Alessio; Giorgi, Alessandra; Maras, Bruno; Cutruzzola', Francesca; Contestabile, Roberto | |
| How pyridoxal 5'-phosphate differentially regulates human cytosolic and mitochondrial serine hydroxymethyltransferase oligomeric state | 2015 | Giardina, Giorgio; Brunotti, Paolo; Fiascarelli, Alessio; Cicalini, A; Costa, Mg; Buckle, Am; DI SALVO, Martino Luigi; Giorgi, Alessandra; Marani, Marina; Paone, Alessio; Rinaldo, Serena; Paiardini, Alessandro; Contestabile, Roberto; Cutruzzola', Francesca | |
| MEN1309/OBT076, a first-in-class antibody–drug conjugate targeting CD205 in solid tumors | 2019 | Merlino, G.; Fiascarelli, A.; Bigioni, M.; Bressan, A.; Carrisi, C.; Bellarosa, D.; Salerno, M.; Bugianesi, R.; Manno, R.; Morales, C. B.; Arribas, J.; Dusek, R. L.; Ackroyd, J. E.; Pham, P. H.; Awdew, R.; Aud, D.; Trang, M.; Lynch, C. M.; Terrett, J.; Wilson, K. E.; Rohlff, C.; Manzini, S.; Pellacani, A.; Binaschi, M. | |
| Molecular mechanism of pdxr - a transcriptional activator involved in the regulation of vitamin b biosynthesis in the probiotic bacterium Bacillus clausii | 2015 | Tramonti, Angela; Fiascarelli, Alessio; Milano, Teresa; DI SALVO, Martino Luigi; Nogués, Isabel; Pascarella, Stefano; Contestabile, Roberto | |
| Screening and in vitro testing of antifolate inhibitors of human cytosolic serine hydroxymethyltransferase | 2015 | Paiardini, Alessandro; Fiascarelli, Alessio; Rinaldo, Serena; Daidone, Frederick; Giardina, Giorgio; Koes, Dr; Parroni, Alessia; Montini, G; Marani, Marina; Paone, Alessio; Mcdermott, La; Contestabile, Roberto; Cutruzzola', Francesca | |
| Serine, Glycine, One-carbon (SGOC) Metabolism and Cancer: Characterization and Inhibition of Serine Hydroxymethyltransferase | 2015 | Fiascarelli, Alessio | |
| SHMT1 knockdown induces apoptosis in lung cancer cells by causing uracil misincorporation | 2014 | Paone, Alessio; Marani, Marina; Fiascarelli, Alessio; Rinaldo, Serena; Giardina, Giorgio; Contestabile, Roberto; Paiardini, Alessandro; Cutruzzola', Francesca |