LANZILLOTTA, SIMONA
LANZILLOTTA, SIMONA
DIPARTIMENTO DI SCIENZE BIOCHIMICHE "ALESSANDRO ROSSI FANELLI"
Altered mitochondrial unfolded protein response and protein quality control promote oxidative distress in down syndrome brain
2025 Lanzillotta, Simona; Esteve, Daniel; Lanzillotta, Chiara; Tramutola, Antonella; Lloret, Ana; Forte, Elena; Pesce, Vito; Picca, Anna; Di Domenico, Fabio; Perluigi, Marzia; Barone, Eugenio
Biliverdin reductase-A integrates insulin signaling with mitochondrial metabolism through phosphorylation of GSK3β
2024 Lanzillotta, Chiara; Tramutola, Antonella; Lanzillotta, Simona; Greco, Viviana; Pagnotta, Sara; Sanchini, Caterina; Di Angelantonio, Silvia; Forte, Elena; Rinaldo, Serena; Paone, Alessio; Cutruzzolà, Francesca; Cimini, Flavia Agata; Barchetta, Ilaria; Cavallo, Maria Gisella; Urbani, Andrea; Butterfield, D Allan; Di Domenico, Fabio; Paul, Bindu D; Perluigi, Marzia; Duarte, Joao M N; Barone, Eugenio
Dynamic changes of BVRA protein levels occur in response to insulin: a pilot study in humans
2023 Cimini, Flavia Agata; Tramutola, Antonella; Barchetta, Ilaria; Ceccarelli, Valentina; Gangitano, Elena; Lanzillotta, Simona; Lanzillotta, Chiara; Cavallo, Maria Gisella; Barone, Eugenio
Enhancing protein O-GlcNAcylation in down syndrome mice mitigates memory dysfunctions through the rescue of mitochondrial bioenergetics, stress responses and pathological markers
2025 Lanzillotta, Chiara; Prestia, Francesca; Greco, Viviana; Iavarone, Federica; Cordella, Federica; Sette, Chiara; Forte, Elena; Tramutola, Antonella; Lanzillotta, Simona; Cassano, Tommaso; Di Angelantonio, Silvia; Urbani, Andrea; Barone, Eugenio; Perluigi, Marzia; Di Domenico, Fabio
GDF-11, GDF-15, Jag-1, and leptin in neuronal-derived extracellular vesicles as aging-related biomarkers to identify individuals at risk of Alzheimer's dementia. A pilot study
2026 Lanzillotta, Simona; Boccardi, Virginia; Zulli, Barbara; Napoli, Alessandro; Paolozzi, Gabriele; Angelini, Roberta; Ruzicka, Barbara; Fratini, Federica; Guazzarini, Anna Giulia; Scamosci, Michela; Bastiani, Patrizia; Alunno, Martina; Westman, Eric; Di Domenico, Fabio; Perluigi, Marzia; Tramutola, Antonella; Cecchetti, Roberta; Mazza, Tommaso; Butterfield, D Allan; Mecocci, Patrizia; Barone, Eugenio
Intranasal administration of KYCCSRK peptide rescues brain insulin signaling activation and reduces Alzheimer’s disease-like neuropathology in a mouse model for Down syndrome
2023 Tramutola, Antonella; Lanzillotta, Simona; Aceto, Giuseppe; Pagnotta, Sara; Ruffolo, Gabriele; Cifelli, Pierangelo; Marini, Federico; Ripoli, Cristian; Palma, Eleonora; Grassi, Claudio; DI DOMENICO, Fabio; Perluigi, Marzia; Barone, Eugenio
Metabolic breakdown: Linking insulin resistance and mitochondrial dysfunction to neurodegeneration in Alzheimer’s disease
2026 Lanzillotta, Simona; Rolfi, Lucrezia Romana; Zulli, Barbara; Barone, Eugenio
Sex-dependent brain-specific alterations of insulin signalling uncover early molecular mechanisms leading to cognitive decline
2023 Lanzillotta, Simona
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| Altered mitochondrial unfolded protein response and protein quality control promote oxidative distress in down syndrome brain | 2025 | Lanzillotta, Simona; Esteve, Daniel; Lanzillotta, Chiara; Tramutola, Antonella; Lloret, Ana; Forte, Elena; Pesce, Vito; Picca, Anna; Di Domenico, Fabio; Perluigi, Marzia; Barone, Eugenio | |
| Biliverdin reductase-A integrates insulin signaling with mitochondrial metabolism through phosphorylation of GSK3β | 2024 | Lanzillotta, Chiara; Tramutola, Antonella; Lanzillotta, Simona; Greco, Viviana; Pagnotta, Sara; Sanchini, Caterina; Di Angelantonio, Silvia; Forte, Elena; Rinaldo, Serena; Paone, Alessio; Cutruzzolà, Francesca; Cimini, Flavia Agata; Barchetta, Ilaria; Cavallo, Maria Gisella; Urbani, Andrea; Butterfield, D Allan; Di Domenico, Fabio; Paul, Bindu D; Perluigi, Marzia; Duarte, Joao M N; Barone, Eugenio | |
| Dynamic changes of BVRA protein levels occur in response to insulin: a pilot study in humans | 2023 | Cimini, Flavia Agata; Tramutola, Antonella; Barchetta, Ilaria; Ceccarelli, Valentina; Gangitano, Elena; Lanzillotta, Simona; Lanzillotta, Chiara; Cavallo, Maria Gisella; Barone, Eugenio | |
| Enhancing protein O-GlcNAcylation in down syndrome mice mitigates memory dysfunctions through the rescue of mitochondrial bioenergetics, stress responses and pathological markers | 2025 | Lanzillotta, Chiara; Prestia, Francesca; Greco, Viviana; Iavarone, Federica; Cordella, Federica; Sette, Chiara; Forte, Elena; Tramutola, Antonella; Lanzillotta, Simona; Cassano, Tommaso; Di Angelantonio, Silvia; Urbani, Andrea; Barone, Eugenio; Perluigi, Marzia; Di Domenico, Fabio | |
| GDF-11, GDF-15, Jag-1, and leptin in neuronal-derived extracellular vesicles as aging-related biomarkers to identify individuals at risk of Alzheimer's dementia. A pilot study | 2026 | Lanzillotta, Simona; Boccardi, Virginia; Zulli, Barbara; Napoli, Alessandro; Paolozzi, Gabriele; Angelini, Roberta; Ruzicka, Barbara; Fratini, Federica; Guazzarini, Anna Giulia; Scamosci, Michela; Bastiani, Patrizia; Alunno, Martina; Westman, Eric; Di Domenico, Fabio; Perluigi, Marzia; Tramutola, Antonella; Cecchetti, Roberta; Mazza, Tommaso; Butterfield, D Allan; Mecocci, Patrizia; Barone, Eugenio | |
| Intranasal administration of KYCCSRK peptide rescues brain insulin signaling activation and reduces Alzheimer’s disease-like neuropathology in a mouse model for Down syndrome | 2023 | Tramutola, Antonella; Lanzillotta, Simona; Aceto, Giuseppe; Pagnotta, Sara; Ruffolo, Gabriele; Cifelli, Pierangelo; Marini, Federico; Ripoli, Cristian; Palma, Eleonora; Grassi, Claudio; DI DOMENICO, Fabio; Perluigi, Marzia; Barone, Eugenio | |
| Metabolic breakdown: Linking insulin resistance and mitochondrial dysfunction to neurodegeneration in Alzheimer’s disease | 2026 | Lanzillotta, Simona; Rolfi, Lucrezia Romana; Zulli, Barbara; Barone, Eugenio | |
| Sex-dependent brain-specific alterations of insulin signalling uncover early molecular mechanisms leading to cognitive decline | 2023 | Lanzillotta, Simona |