ZWERGEL, CLEMENS
ZWERGEL, CLEMENS
DIPARTIMENTO DI CHIMICA E TECNOLOGIE DEL FARMACO
1,4-Dihydropyridines Active on the SIRT1/AMPK Pathway Ameliorate Skin Repair and Mitochondrial Function and Exhibit Inhibition of Proliferation in Cancer Cells
2016 Valente, Sergio; Mellini, Paolo; Spallotta, Francesco; Carafa, Vincenzo; Nebbioso, Angela; Polletta, Lucia; Carnevale, Ilaria; Saladini, Serena; Trisciuoglio, Daniela; Gabellini, Chiara; Tardugno, Maria; Zwergel, Clemens; Cencioni, Chiara; Atlante, Sandra; Moniot, Sébastien; Steegborn, Clemens; Budriesi, Roberta; Tafani, Marco; Del Bufalo, Donatella; Altucci, Lucia; Gaetano, Carlo; Mai, Antonello
A quinoline-based DNA methyltransferase inhibitor as a possible adjuvant in osteosarcoma therapy
2018 Manara, Maria Cristina; Valente, Sergio; Cristalli, Camilla; Nicoletti, Giordano; Landuzzi, Lorena; Zwergel, Clemens; Mazzone, Roberta; Stazi, Giulia; Arimondo, Paola B.; Pasello, Michela; Guerzoni, Clara; Picci, Piero; Nanni, Patrizia; Lollini, Pier-Luigi; Mai, Antonello; Scotlandi, Katia
Abstract 2946: Effects of two novel quinoline-based non-nucleoside DNA methyltransferase inhibitors against bone sarcomas
2015 Manara, Maria Cristina; Valente, Sergio; Cristalli, Camilla; Baricordi, Cristina; Zwergel, Clemens; Arimondo, Paola B; Picci, Piero; Mai, Antonello; Scotlandi, Katia
Acute and chronic neurobehavioral effects of the designer drug and bath salt constituent 3,4-methylenedioxypyrovalerone in the rat
2019 ATEHORTUA MARTINEZ, LUISA ALESSANDRA; Masniere, Cyriaque; Campolongo, Patrizia; Chasseigneaux, Stéphanie; Callebert, Jacques; Zwergel, Clemens; Mai, Antonello; Laplanche, Jean-Louis; Chen, Huixiong; Etheve-Quelquejeu, Mélanie; Mégarbane, Bruno; Benturquia, Nadia
Amphetamine and the Smart Drug 3,4-Methylenedioxypyrovalerone (MDPV) Induce Generalization of Fear Memory in Rats
2019 Colucci, Paola; Mancini, Giulia Federica; Santori, Alessia; Zwergel, Clemens; Mai, Antonello; Trezza, Viviana; Roozendaal, Benno; Campolongo, Patrizia
Amphetamine modulation of long-term object recognition memory in rats: influence of stress
2021 Colucci, Paola; Santori, Alessia; Romanelli, Luca; Zwergel, Clemens; Mai, Antonello; Scaccianoce, Sergio; Campolongo, Patrizia
Application of small epigenetic modulators in pediatric medulloblastoma
2018 Zwergel, Clemens; Romanelli, Annalisa; Stazi, Giulia; Besharat, Zein Mersini; Catanzaro, Giuseppina; Tafani, Marco; Valente, Sergio; Mai, Antonello
Aurones: Interesting Natural and Synthetic Compounds with Emerging Biological Potential
2012 Zwergel, Clemens; F., Gaascht; Valente, Sergio; M., Diederich; D., Bagrel; G., Kirsch
Chemically diverse S. mansoni HDAC8 inhibitors reduced viability in worm larval and adult stages
2023 Noce, Beatrice; Di Bello, Elisabetta; Zwergel, Clemens; Fioravanti, Rossella; Valente, Sergio; Rotili, Dante; Masotti, Andrea; Ansari, Mohammad Salik Zeya; Trisciuoglio, Daniela; Chakrabarti, Alokta; Romier, Christophe; Robaa, Dina; Sippl, Wolfgang; Jung, Manfred; Häberli, Cécile; Keiser, Jennifer; Mai, Antonello
Design of first-in-class dual EZH2/HDAC inhibitor: biochemical activity and biological evaluation in cancer cells
2020 Romanelli, Annalisa; Stazi, Giulia; Fioravanti, Rossella; Zwergel, Clemens; Di Bello, Elisabetta; Pomella, Silvia; Perrone, Clara; Battistelli, Cecilia; Strippoli, Raffaele; Tripodi, Marco; del Bufalo, Donatella; Rota, Rossella; Trisciuoglio, Daniela; Mai, Antonello; Valente, Sergio
Detrimental effects of the 'bath salt' methylenedioxypyrovalerone on social play behavior in male rats
2020 Schiavi, Sara; Melancia, Francesca; Carbone, Emilia; Buzzelli, Valeria; Manduca, Antonia; Peinado, Patricia Jiménez; Zwergel, Clemens; Mai, Antonello; Campolongo, Patrizia; Vanderschuren, Louk J M J; Trezza, Viviana
Development of alkyl glycerone phosphate synthase inhibitors: Structure-activity relationship and effects on ether lipids and epithelial-mesenchymal transition in cancer cells
2019 Stazi, Giulia; Battistelli, Cecilia; Piano, Valentina; Mazzone, Roberta; Marrocco, Biagina; Marchese, Sara; Louie, Sharon M.; Zwergel, Clemens; Antonini, Lorenzo; Patsilinakos, Alexandros; Ragno, Rino; Viviano, Monica; Sbardella, Gianluca; Ciogli, Alessia; Fabrizi, Giancarlo; Cirilli, Roberto; Strippoli, Raffaele; Marchetti, Alessandra; Tripodi, Marco; Nomura, Daniel K.; Mattevi, Andrea; Mai, Antonello; Valente, Sergio
Discovery of phenylselenoether-hydantoin hybrids as ABCB1 efflux pump modulating agents with cytotoxic and antiproliferative actions in resistant T-lymphoma
2020 Ali, Wesam; Spengler, Gabriella; Kincses, Annamária; Nové, Márta; Battistelli, Cecilia; Latacz, Gniewomir; Starek, Małgorzata; Dąbrowska, Monika; Honkisz-Orzechowska, Ewelina; Romanelli, Annalisa; Rasile, Manuela Monica; Szymańska, Ewa; Jacob, Claus; Zwergel, Clemens; Handzlik, Jadwiga
Discovery of the first human arylsulfatase a reversible inhibitor impairing mouse oocyte fertilization
2020 Caroselli, Silvia; Zwergel, Clemens; Pirolli, Adele; Sabatino, Manuela; Xu, Zhanjie; Kirsch, Gilbert; Mai, Antonello; Colotti, Gianni; Altieri, Fabio; Canipari, Rita; Valente, Sergio; Ragno, Rino
DNA methyltransferases Inhibitors from natural sources
2016 Zwergel, Clemens; Valente, Sergio; Mai, Antonello
Editorial: chemical innovative approaches in cancer molecular medicine and translational clinical research
2020 Benedetti, Rosaria; Conte, Mariarosaria; Dell'Aversana, Carmela; Hansen, Finn K.; Zwergel, Clemens
Editorial: Frontiers in Chemistry: rising stars 2022
2023 Brites, Carlos D. S.; Contini, Daniele; He, Xiao-Peng; Liu, Tianqing; Moosa, Basem; Pannico, Marianna; Rashed, Mohamed Nageeb; Qiu, Yunping; Zwergel, Clemens
Effect of Class II HDAC inhibition on glutamate transporter expression and survival in SOD1-ALS mice
2017 Lapucci, Andrea; Cavone, Leonardo; Buonvicino, Daniela; Felici, Roberta; Gerace, Elisabetta; Zwergel, Clemens; Valente, Sergio; Mai, Antonello; Chiarugi, Alberto
Effects of class II-selective histone deacetylase inhibitor on neuromuscular function and disease progression in SOD1-ALS mice
2018 Buonvicino, Daniela; Felici, Roberta; Ranieri, GIUSEPPE ANTONIO; Caramelli, Riccardo; Lapucci, Andrea; Cavone, Leonardo; Muzzi, Mirko; Di Pietro, Lorena; Bernardini, Camilla; Zwergel, Clemens; Valente, Sergio; Mai, Antonello; Chiarugi, Alberto
Effects of structurally different HDAC inhibitors against Trypanosoma cruzi, Leishmania, and Schistosoma mansoni
2022 Di Bello, Elisabetta; Noce, Beatrice; Fioravanti, Rossella; Zwergel, Clemens; Valente, Sergio; Rotili, Dante; Fianco, Giulia; Trisciuoglio, Daniela; Mourão, Marina M; Sales, Policarpo; Lamotte, Suzanne; Prina, Eric; Späth, Gerald F; Häberli, Cécile; Keiser, Jennifer; Mai, Antonello
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| 1,4-Dihydropyridines Active on the SIRT1/AMPK Pathway Ameliorate Skin Repair and Mitochondrial Function and Exhibit Inhibition of Proliferation in Cancer Cells | 2016 | Valente, Sergio; Mellini, Paolo; Spallotta, Francesco; Carafa, Vincenzo; Nebbioso, Angela; Polletta, Lucia; Carnevale, Ilaria; Saladini, Serena; Trisciuoglio, Daniela; Gabellini, Chiara; Tardugno, Maria; Zwergel, Clemens; Cencioni, Chiara; Atlante, Sandra; Moniot, Sébastien; Steegborn, Clemens; Budriesi, Roberta; Tafani, Marco; Del Bufalo, Donatella; Altucci, Lucia; Gaetano, Carlo; Mai, Antonello | |
| A quinoline-based DNA methyltransferase inhibitor as a possible adjuvant in osteosarcoma therapy | 2018 | Manara, Maria Cristina; Valente, Sergio; Cristalli, Camilla; Nicoletti, Giordano; Landuzzi, Lorena; Zwergel, Clemens; Mazzone, Roberta; Stazi, Giulia; Arimondo, Paola B.; Pasello, Michela; Guerzoni, Clara; Picci, Piero; Nanni, Patrizia; Lollini, Pier-Luigi; Mai, Antonello; Scotlandi, Katia | |
| Abstract 2946: Effects of two novel quinoline-based non-nucleoside DNA methyltransferase inhibitors against bone sarcomas | 2015 | Manara, Maria Cristina; Valente, Sergio; Cristalli, Camilla; Baricordi, Cristina; Zwergel, Clemens; Arimondo, Paola B; Picci, Piero; Mai, Antonello; Scotlandi, Katia | |
| Acute and chronic neurobehavioral effects of the designer drug and bath salt constituent 3,4-methylenedioxypyrovalerone in the rat | 2019 | ATEHORTUA MARTINEZ, LUISA ALESSANDRA; Masniere, Cyriaque; Campolongo, Patrizia; Chasseigneaux, Stéphanie; Callebert, Jacques; Zwergel, Clemens; Mai, Antonello; Laplanche, Jean-Louis; Chen, Huixiong; Etheve-Quelquejeu, Mélanie; Mégarbane, Bruno; Benturquia, Nadia | |
| Amphetamine and the Smart Drug 3,4-Methylenedioxypyrovalerone (MDPV) Induce Generalization of Fear Memory in Rats | 2019 | Colucci, Paola; Mancini, Giulia Federica; Santori, Alessia; Zwergel, Clemens; Mai, Antonello; Trezza, Viviana; Roozendaal, Benno; Campolongo, Patrizia | |
| Amphetamine modulation of long-term object recognition memory in rats: influence of stress | 2021 | Colucci, Paola; Santori, Alessia; Romanelli, Luca; Zwergel, Clemens; Mai, Antonello; Scaccianoce, Sergio; Campolongo, Patrizia | |
| Application of small epigenetic modulators in pediatric medulloblastoma | 2018 | Zwergel, Clemens; Romanelli, Annalisa; Stazi, Giulia; Besharat, Zein Mersini; Catanzaro, Giuseppina; Tafani, Marco; Valente, Sergio; Mai, Antonello | |
| Aurones: Interesting Natural and Synthetic Compounds with Emerging Biological Potential | 2012 | Zwergel, Clemens; F., Gaascht; Valente, Sergio; M., Diederich; D., Bagrel; G., Kirsch | |
| Chemically diverse S. mansoni HDAC8 inhibitors reduced viability in worm larval and adult stages | 2023 | Noce, Beatrice; Di Bello, Elisabetta; Zwergel, Clemens; Fioravanti, Rossella; Valente, Sergio; Rotili, Dante; Masotti, Andrea; Ansari, Mohammad Salik Zeya; Trisciuoglio, Daniela; Chakrabarti, Alokta; Romier, Christophe; Robaa, Dina; Sippl, Wolfgang; Jung, Manfred; Häberli, Cécile; Keiser, Jennifer; Mai, Antonello | |
| Design of first-in-class dual EZH2/HDAC inhibitor: biochemical activity and biological evaluation in cancer cells | 2020 | Romanelli, Annalisa; Stazi, Giulia; Fioravanti, Rossella; Zwergel, Clemens; Di Bello, Elisabetta; Pomella, Silvia; Perrone, Clara; Battistelli, Cecilia; Strippoli, Raffaele; Tripodi, Marco; del Bufalo, Donatella; Rota, Rossella; Trisciuoglio, Daniela; Mai, Antonello; Valente, Sergio | |
| Detrimental effects of the 'bath salt' methylenedioxypyrovalerone on social play behavior in male rats | 2020 | Schiavi, Sara; Melancia, Francesca; Carbone, Emilia; Buzzelli, Valeria; Manduca, Antonia; Peinado, Patricia Jiménez; Zwergel, Clemens; Mai, Antonello; Campolongo, Patrizia; Vanderschuren, Louk J M J; Trezza, Viviana | |
| Development of alkyl glycerone phosphate synthase inhibitors: Structure-activity relationship and effects on ether lipids and epithelial-mesenchymal transition in cancer cells | 2019 | Stazi, Giulia; Battistelli, Cecilia; Piano, Valentina; Mazzone, Roberta; Marrocco, Biagina; Marchese, Sara; Louie, Sharon M.; Zwergel, Clemens; Antonini, Lorenzo; Patsilinakos, Alexandros; Ragno, Rino; Viviano, Monica; Sbardella, Gianluca; Ciogli, Alessia; Fabrizi, Giancarlo; Cirilli, Roberto; Strippoli, Raffaele; Marchetti, Alessandra; Tripodi, Marco; Nomura, Daniel K.; Mattevi, Andrea; Mai, Antonello; Valente, Sergio | |
| Discovery of phenylselenoether-hydantoin hybrids as ABCB1 efflux pump modulating agents with cytotoxic and antiproliferative actions in resistant T-lymphoma | 2020 | Ali, Wesam; Spengler, Gabriella; Kincses, Annamária; Nové, Márta; Battistelli, Cecilia; Latacz, Gniewomir; Starek, Małgorzata; Dąbrowska, Monika; Honkisz-Orzechowska, Ewelina; Romanelli, Annalisa; Rasile, Manuela Monica; Szymańska, Ewa; Jacob, Claus; Zwergel, Clemens; Handzlik, Jadwiga | |
| Discovery of the first human arylsulfatase a reversible inhibitor impairing mouse oocyte fertilization | 2020 | Caroselli, Silvia; Zwergel, Clemens; Pirolli, Adele; Sabatino, Manuela; Xu, Zhanjie; Kirsch, Gilbert; Mai, Antonello; Colotti, Gianni; Altieri, Fabio; Canipari, Rita; Valente, Sergio; Ragno, Rino | |
| DNA methyltransferases Inhibitors from natural sources | 2016 | Zwergel, Clemens; Valente, Sergio; Mai, Antonello | |
| Editorial: chemical innovative approaches in cancer molecular medicine and translational clinical research | 2020 | Benedetti, Rosaria; Conte, Mariarosaria; Dell'Aversana, Carmela; Hansen, Finn K.; Zwergel, Clemens | |
| Editorial: Frontiers in Chemistry: rising stars 2022 | 2023 | Brites, Carlos D. S.; Contini, Daniele; He, Xiao-Peng; Liu, Tianqing; Moosa, Basem; Pannico, Marianna; Rashed, Mohamed Nageeb; Qiu, Yunping; Zwergel, Clemens | |
| Effect of Class II HDAC inhibition on glutamate transporter expression and survival in SOD1-ALS mice | 2017 | Lapucci, Andrea; Cavone, Leonardo; Buonvicino, Daniela; Felici, Roberta; Gerace, Elisabetta; Zwergel, Clemens; Valente, Sergio; Mai, Antonello; Chiarugi, Alberto | |
| Effects of class II-selective histone deacetylase inhibitor on neuromuscular function and disease progression in SOD1-ALS mice | 2018 | Buonvicino, Daniela; Felici, Roberta; Ranieri, GIUSEPPE ANTONIO; Caramelli, Riccardo; Lapucci, Andrea; Cavone, Leonardo; Muzzi, Mirko; Di Pietro, Lorena; Bernardini, Camilla; Zwergel, Clemens; Valente, Sergio; Mai, Antonello; Chiarugi, Alberto | |
| Effects of structurally different HDAC inhibitors against Trypanosoma cruzi, Leishmania, and Schistosoma mansoni | 2022 | Di Bello, Elisabetta; Noce, Beatrice; Fioravanti, Rossella; Zwergel, Clemens; Valente, Sergio; Rotili, Dante; Fianco, Giulia; Trisciuoglio, Daniela; Mourão, Marina M; Sales, Policarpo; Lamotte, Suzanne; Prina, Eric; Späth, Gerald F; Häberli, Cécile; Keiser, Jennifer; Mai, Antonello |