Sfoglia per Autore
Dihalo Indolyl Aryl Sulfones (IASs) Highly Active In Vitro Against HIV-1 WT and Variants Carrying NNRTI Resistance Mutations.
2005 DE MARTINO, G.; LA REGINA, Giuseppe; Ragno, Rino; Coluccia, Antonio; Maga, G.; Artico, Marino; Silvestri, Romano
Novel 1-[2-(Diarylmethoxy)ethyl]-2-methyl-5-nitroimidazoles as HIV-1 Non-Nucleoside Reverse Transcriptase Inhibitors. A Structure-Activity Relationship Investigation.
2005 DE MARTINO, G.; LA REGINA, Giuseppe; Ragno, Rino; Loddo, R.; LA COLLA, M.; Mura, M.; LA COLLA, P.; Maga, G.; Crespan, E.; Artico, Marino; Silvestri, Romano
Chiral resolution and binding study of 1,3,4,14b-tetrahydro-2,10-dimethyl-2H,10H-pyrazino[2,1-d]pyrrolo[1,2-b] [1,2,5]benzotriazepine (10-methyl-10-azaaptazepine) and 2-methyl-1,3,4,14b-tetrahydro-2H-pyrazino[2,1-d]pyrrolo[1,2-b][1,2,5]-benzothiadiazepine 10,10-dioxide (tiaaptazepine).
2005 DE MARTINO, G.; LA REGINA, Giuseppe; LA TORRE, F.; Cirilli, R.; Mereghetti, I.; Cagnotto, A.; Artico, Marino; Silvestri, Romano
Design, Synthesis and Biological Evaluation of New Pyrrole MAO-B Inhibitors.
2005 LA REGINA, Giuseppe; DE MARTINO, G.; Robortaccio, G.; Ragno, Rino; Befani, O.; Agostinelli, Enzo; Turini, Paola; Fabi, A.; Artico, Marino; Silvestri, Romano
High potency of indolyl aryl sulfone nonnucleoside inhibitors towards drug-resistant human immunodeficiency virus type 1 reverse transcriptase mutants is due to selective targeting of different mechanistic forms of the enzyme
2005 R., Cancio; Silvestri, Romano; Ragno, Rino; Artico, Marino; G., De Martino; LA REGINA, Giuseppe; E., Crespan; S., Zanoli; U., Hubscher; S., Spadari; G., Maga
Indolyl aryl Sulfones (IASs): Development of highly potent NNRTIs active against wt-HIV-1 and clinically relevant drug resistant mutants
2005 Silvestri, Romano; Artico, Marino
Docking and 3-D QSAR Studies on Indolyl Aryl Sulfones. Binding Mode Exploration at the HIV-1 Reverse Transcriptase Non-Nucleoside Binding Site and Design of Highly Active N-(2-Hydroxyethyl)carboxamide and N-(2-Hydroxyethyl)carbohydrazide Derivatives.
2005 Ragno, Rino; Artico, Marino; DE MARTINO, G.; LA REGINA, Giuseppe; Coluccia, Antonio; DI PASQUALI, A.; Silvestri, Romano
Comparative study between the polysaccharidebased Chiralcel OJ and Chiralcel OD CSPs in chromatographic enantioseparation of imidazole analogues of Fluoxetine and Miconazole.
2005 Cirilli, R.; Ferretti, R.; Gallinella, B.; LA TORRE, F.; LA REGINA, Giuseppe; Silvestri, Romano
Arylthioindoles, Potent Inhibitors of Tubulin Polymerization: Structure-Activity Relationships and Molecular Modeling Studies.
2006 LA REGINA, Giuseppe; Brancale, A.; DE MARTINO, G.; Artico, Marino; Silvestri, Romano
Synthesis and evaluation of novel potential HCV helicase ihibitors.
2006 Brancale, A; Vlachakis, D; Barbera, Mc; Silvestri, Romano; Berry, C; Netys, J.
Arylthioindole tubulin polymerization inhibitors and their preparation, pharmaceutical compositions, and methods of treating or preventing cancer using them
2006 Hamel, E; Silvestri, Romano; Brancale, A.
Direct HPLC enantioseparation of chiral aptazepine derivatives on coated and bonded polysaccharide-based chiral stationery phases.
2006 Cirilli, R; Orlando, Viviana; Ferretti, R; Turchetto, L; Silvestri, Romano; DE MARTINO, G; LA TORRE, F.
Indolyl aryl sulphones as HIV-1 non-nucleoside reverse transcriptase inhibitors: synthesis, biological evaluation and binding mode studies of new derivatives at indole-2-carbxamide.
2006 DE MARTINO, G.; LA REGINA, Giuseppe; Ragno, Rino; Coluccia, Antonio; Bergamini, A.; Caprini, C.; Sinistro, A.; Maga, G.; Crespan, E.; Artico, Marino; Silvestri, Romano
Ariltioindoli, potenti inibitori della polimerizzazione della tubulina
2006 LA REGINA, Giuseppe; Brancale, A.; Silvestri, Romano
New Indolyl Aryl Sulfones (IASs) as potent anti-HIV agents.
2006 Piscitelli, Francesco; LA REGINA, Giuseppe; DE MARTINO, G.; Artico, Marino; Silvestri, Romano
Structure-Based and 3-D QSAR Drug Design of New Indolyl Aryl Sulfones.
2006 Coluccia, Antonio; Ragno, Rino; LA REGINA, Giuseppe; Artico, Marino; Silvestri, Romano
Indole nucleus as a selected pharmacophore for the design of novel highly anti-HIV RT inhibitors and also capable to inhibit tumor cell replication.
2006 Silvestri, Romano; Artico, Marino; LA REGINA, Giuseppe; Piscitelli, Francesco; Coluccia, Antonio; Ragno, Rino
New Arylthioindoles: Potent Inhibitors of Tubulin Polymerization. 2. Structure-Activity Relationships and Molecular Modeling Studies.
2006 DE MARTINO, G.; Edler, M. C.; LA REGINA, Giuseppe; Coluccia, Antonio; Barbera, M. C.; Barrow, D.; Nicholson, R. I.; Chiosis, G.; Brancale, A.; Hamel, E.; Artico, Marino; Silvestri, Romano
Synthesis of Pyrrolo[1,2-b][1,2,5]benzothiadiazepines (PBTDs): New Agents for the Treatment of Chronic Myelogenus Leukemia (CML).
2006 DE MARTINO, G.; LA REGINA, Giuseppe; Artico, Marino; Silvestri, Romano; Lavecchia, A.; Novellino, E.
Improved 3-D QSAR Model on Indolyl Aryl Sulfones: Design of potent anti-HIV-1 active against both wild type and mutant form of RT.
2006 Coluccia, Antonio; Ragno, Rino; LA REGINA, Giuseppe; Silvestri, Romano
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