Early diagnosis of tuberculosis (TB) is one of the primary challenges in curtailing the spread of TB. This study aimed to determine the diagnostic accuracy of Xpert MTB/RIF for the identification of M. tuberculosis in clinical specimens, and compare this to a microscopist’s diagnostic performance. Xpert MTB/ RIF was positive in all specimens with culture-confirmed TB, giving a higher sensitivity than the smear microscopy (100% versus 63%). The use of the Xpert MTB/RIF, as part of routine assay, permits rapid diagnosis of TB and enables clinicians to start an effective treatment.
Diagnostic accuracy of Xpert MTB/RIF versus smear microscopy in the early diagnosis of tuberculosis in the real life of the “Umberto I” Hospital in Rome / Sauzullo, Ilaria; Rodio, DONATELLA MARIA; Facchinetti, S; Puggioni, Gianluca; DE ANGELIS, Massimiliano; Goldoni, Paola; Vullo, Vincenzo; Mengoni, Fabio; Trancassini, Maria; Pietropaolo, Valeria Antonietta. - In: NEW MICROBIOLOGICA. - ISSN 1121-7138. - ELETTRONICO. - 39:4(2016), pp. 304-306.
Diagnostic accuracy of Xpert MTB/RIF versus smear microscopy in the early diagnosis of tuberculosis in the real life of the “Umberto I” Hospital in Rome
SAUZULLO, Ilaria;RODIO, DONATELLA MARIA;PUGGIONI, Gianluca;DE ANGELIS, Massimiliano;GOLDONI, Paola;VULLO, Vincenzo;MENGONI, Fabio;TRANCASSINI, Maria;PIETROPAOLO, Valeria Antonietta
2016
Abstract
Early diagnosis of tuberculosis (TB) is one of the primary challenges in curtailing the spread of TB. This study aimed to determine the diagnostic accuracy of Xpert MTB/RIF for the identification of M. tuberculosis in clinical specimens, and compare this to a microscopist’s diagnostic performance. Xpert MTB/ RIF was positive in all specimens with culture-confirmed TB, giving a higher sensitivity than the smear microscopy (100% versus 63%). The use of the Xpert MTB/RIF, as part of routine assay, permits rapid diagnosis of TB and enables clinicians to start an effective treatment.| File | Dimensione | Formato | |
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