This study aimed to explore film forming capacity of a natural polysaccharide, gellan gum (GG), for fabrication of oral thin films (OTFs) for the delivery of drugs [1]. For the development of buccal film with ideal mechanical properties and adequate amount of drug incorporated, concentration of polymer and plasticizer were optimized to obtain films with the highest standard in terms of flexibility and homogeneity [2]. Moreover, attention was also paid to the exploration of opportune dissolution tests able to discriminate the release profiles of drugs from polymeric thin films.
Manufacturing and characterization of polymeric thin films for buccal delivery of drugs / Varani, Gabriele; Adrover, Alessandra; Nardoni, Martina; Settimio, Pacelli; Paolicelli, Patrizia; Petralito, Stefania; Casadei, Maria Antonietta. - CD-ROM. - 1:(2016), pp. 37-37. (Intervento presentato al convegno 10th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology tenutosi a Glasgow).
Manufacturing and characterization of polymeric thin films for buccal delivery of drugs
VARANI, GABRIELE;ADROVER, Alessandra;NARDONI, MARTINA;PAOLICELLI, PATRIZIA;PETRALITO, Stefania;CASADEI, Maria Antonietta
2016
Abstract
This study aimed to explore film forming capacity of a natural polysaccharide, gellan gum (GG), for fabrication of oral thin films (OTFs) for the delivery of drugs [1]. For the development of buccal film with ideal mechanical properties and adequate amount of drug incorporated, concentration of polymer and plasticizer were optimized to obtain films with the highest standard in terms of flexibility and homogeneity [2]. Moreover, attention was also paid to the exploration of opportune dissolution tests able to discriminate the release profiles of drugs from polymeric thin films.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
