Genetic variants in the immunomodulatory gene mannose-binding lectin 2 (MBL2), were associated with risk, severity, and frequency of viral infections. In a case-control setting, we investigated the association of MBL2 functional polymorphisms with Human Papillomas Virus (HPV) infection. No differences between cases (HPV+) and controls (HPV-) were found in the distribution of each single genotypes or allele. Haplotype analysis did not show any difference between HPV+ and HPV- groups.
Lack of association between genetic variants in the mannose-binding lectin 2 (MBL2) gene and HPV infection / Paola, Parrella; Davide, Seripa; Maria G., Matera; Monica, Rinaldi; Emanuela, Signori; Carolina, Gravina; Antonietta P., Gallo; Prencipe, Massimiliano; Elvira, Grandone; Luciano, Mariani; Paola, Cordiali; A., Di Carlo; Stentella, Patrizia; Pachi', Antonio; Vito M., Fazio. - In: EUROPEAN JOURNAL OF EPIDEMIOLOGY. - ISSN 0393-2990. - 22:3(2007), pp. 159-162. [10.1007/s10654-007-9111-8]
Lack of association between genetic variants in the mannose-binding lectin 2 (MBL2) gene and HPV infection
PRENCIPE, Massimiliano;STENTELLA, Patrizia;PACHI', Antonio;
2007
Abstract
Genetic variants in the immunomodulatory gene mannose-binding lectin 2 (MBL2), were associated with risk, severity, and frequency of viral infections. In a case-control setting, we investigated the association of MBL2 functional polymorphisms with Human Papillomas Virus (HPV) infection. No differences between cases (HPV+) and controls (HPV-) were found in the distribution of each single genotypes or allele. Haplotype analysis did not show any difference between HPV+ and HPV- groups.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
