The authors report the results of a study conducted on 136 patients affected by breast cancer under treatment with tamoxifen at a daily dose of 20 mg who underwent a strict follow-up including endometrial surveillance. The cytologic evaluation of the endometrium was performed on smears obtained by the endocyte sampling. The results were in accordance with what is reported in the literature. Forty cases presented with hyperplasia which was atypical in two cases. Only in one case did histology show a well differentiated adenocarcinoma. In 25 cases the endometrium resulted to be proliferative in accordance with the effect of tamoxifen, while the remaining 67 cases were atrophic. The investigation was not possible in four cases due to stenosis. In our study the endocyte sampler resulted to be an economic, simple and painless cytologic device, suitable for clinical use because of its low incidence of false positives.

Cytologic endometrial surveillance in tamoxifen-treated women / Labi, Fortunata Lucille; Meggiorini, Maria Letizia; Nusiner, Maria Paola; A., Di Lillo; Cascialli, Gian Luca; N. O., Ogbonna; Cosmi, Ermelando. - In: EUROPEAN JOURNAL OF GYNAECOLOGICAL ONCOLOGY. - ISSN 0392-2936. - 23:6(2002), pp. 537-539.

Cytologic endometrial surveillance in tamoxifen-treated women

LABI, Fortunata Lucille;MEGGIORINI, Maria Letizia;NUSINER, Maria Paola;CASCIALLI, Gian Luca;COSMI, Ermelando
2002

Abstract

The authors report the results of a study conducted on 136 patients affected by breast cancer under treatment with tamoxifen at a daily dose of 20 mg who underwent a strict follow-up including endometrial surveillance. The cytologic evaluation of the endometrium was performed on smears obtained by the endocyte sampling. The results were in accordance with what is reported in the literature. Forty cases presented with hyperplasia which was atypical in two cases. Only in one case did histology show a well differentiated adenocarcinoma. In 25 cases the endometrium resulted to be proliferative in accordance with the effect of tamoxifen, while the remaining 67 cases were atrophic. The investigation was not possible in four cases due to stenosis. In our study the endocyte sampler resulted to be an economic, simple and painless cytologic device, suitable for clinical use because of its low incidence of false positives.
2002
adenocarcinoma; endocyte sampling; hyperplasia; tamoxifen
01 Pubblicazione su rivista::01a Articolo in rivista
Cytologic endometrial surveillance in tamoxifen-treated women / Labi, Fortunata Lucille; Meggiorini, Maria Letizia; Nusiner, Maria Paola; A., Di Lillo; Cascialli, Gian Luca; N. O., Ogbonna; Cosmi, Ermelando. - In: EUROPEAN JOURNAL OF GYNAECOLOGICAL ONCOLOGY. - ISSN 0392-2936. - 23:6(2002), pp. 537-539.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/7833
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