This study investigated the relationships between ovarian endometrioma size, ovarian responsiveness and the number of retrieved oocytes following ovarian stimulation. A prospective study was conducted in a public clinical assisted reproduction centre. A total of 64 infertile women with monolateral endometriomas undergoing IVF or intracytoplasmic sperm injection were included in the study. The total number of follicles, number of follicles ≥16 mm and number of oocytes retrieved of ovaries containing endometrioma and normal ovaries were compared. Multivariate linear regression was used to assess whether number of follicles and collected oocytes varied by endometrioma size, age, basal FSH concentration. Significantly lower numbers of follicles ≥16 mm (P = 0.024) and oocytes retrieved (P = 0.001) in the ovaries containing endometrioma were observed. In patients with endometriomas ≥30 mm, endometrioma size was the most influential contributor to the total number of follicles and oocytes retrieved. Ovarian endometriomas result in reduced response to ovarian stimulation, compared with the response of the contralateral normal ovary in the same individual. In case of endometriomas <30 mm, basal FSH concentration remains the most important prognostic factor for oocyte retrieval. © 2014 Reproductive Healthcare Ltd.

Is there a critical endometrioma size associated with reduced ovarian responsiveness in assisted reproduction techniques? / Maria Elisabetta, Coccia; Francesca, Rizzello; Stefano, Barone; Sara, Pinelli; Erika, Rapalini; Cristiana, Parri; Domenico, Caracciolo; Savvas, Papageorgiou; Gianpaolo, Cima; Gandini, Loredana. - In: REPRODUCTIVE BIOMEDICINE ONLINE. - ISSN 1472-6491. - ELETTRONICO. - 29:2(2014), pp. 259-266. [10.1016/j.rbmo.2014.04.019]

Is there a critical endometrioma size associated with reduced ovarian responsiveness in assisted reproduction techniques?

GANDINI, Loredana
2014

Abstract

This study investigated the relationships between ovarian endometrioma size, ovarian responsiveness and the number of retrieved oocytes following ovarian stimulation. A prospective study was conducted in a public clinical assisted reproduction centre. A total of 64 infertile women with monolateral endometriomas undergoing IVF or intracytoplasmic sperm injection were included in the study. The total number of follicles, number of follicles ≥16 mm and number of oocytes retrieved of ovaries containing endometrioma and normal ovaries were compared. Multivariate linear regression was used to assess whether number of follicles and collected oocytes varied by endometrioma size, age, basal FSH concentration. Significantly lower numbers of follicles ≥16 mm (P = 0.024) and oocytes retrieved (P = 0.001) in the ovaries containing endometrioma were observed. In patients with endometriomas ≥30 mm, endometrioma size was the most influential contributor to the total number of follicles and oocytes retrieved. Ovarian endometriomas result in reduced response to ovarian stimulation, compared with the response of the contralateral normal ovary in the same individual. In case of endometriomas <30 mm, basal FSH concentration remains the most important prognostic factor for oocyte retrieval. © 2014 Reproductive Healthcare Ltd.
2014
ovarian stimulation; endometrioma; oocytes; ivf; assisted reproduction
01 Pubblicazione su rivista::01a Articolo in rivista
Is there a critical endometrioma size associated with reduced ovarian responsiveness in assisted reproduction techniques? / Maria Elisabetta, Coccia; Francesca, Rizzello; Stefano, Barone; Sara, Pinelli; Erika, Rapalini; Cristiana, Parri; Domenico, Caracciolo; Savvas, Papageorgiou; Gianpaolo, Cima; Gandini, Loredana. - In: REPRODUCTIVE BIOMEDICINE ONLINE. - ISSN 1472-6491. - ELETTRONICO. - 29:2(2014), pp. 259-266. [10.1016/j.rbmo.2014.04.019]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/687255
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